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| 1 | Establishment of a Rat Model: Associating Liver Partition with Portal Vein Ligation for Staged Hepatectomy显示文摘 | Weiwei Wei Tianjiao Zhang Sara Zafarnia Andrea Schenk Chichi Xie Chunyi Kan Olaf Dirsch Utz Settmacher Uta Dahmen | 2015 | Surgery2015，，： | 1 |
| 2 | Marginal Hepatectomy in the Rat: From Anatomy to Surgery显示文摘 | Nodir Madrahimov Olaf Dirsch Christoph Broelsch Uta Dahmen | 2006 | Annals of Surgery2006，，1： | 1 |
| 3 | Prolonged Cold Ischemia Does Not Trigger Lethal Rejection or Accelerate the Acute Rejection in Two Allogeneic Rat Liver Transplantation Models显示文摘 | Hao Jin Uta Dahmen Anding Liu Hai Huang Yanli Gu Olaf Dirsch | 2012 | Journal of Surgical Research2012，，2： | 1 |
| 4 | Synergistic effects of a novel nanoporous stent coating and tacrolimus on intima proliferation in rabbits显示文摘 | Heinrich Wieneke Olaf Dirsch Thomas Sawitowski | 2003 | Catheterization and Cardiovascular Interventions2003，60，3： | 1 |
| 5 | Chronic Lithium Treatment Protects Against Liver Ischemia/Reperfusion Injury in Rats显示文摘 | Anding Liu Haoshu Fang Uta Dahmen Olaf Dirsch | 2013 | Liver Transpl2013，，7： | 1 |
| 6 | 大鼠小体积肝移植后肝细胞再生的研究显示文摘目的探讨小体积肝移植术后肝再生的情况。方法建立大鼠30%原位肝移植模型,实验分为肝切除(PH)组、全肝移植(OLT)组和30%小体积肝移植(30%POLT)组,观察1w生存率,并于术后1、2、3、7d检测肝细胞增殖活性、肝功能和肝组织学变化。结果各组1w生存率均为100%;30%POLT组术后2d达到增殖高峰,峰值与PH组无差异(P>0.05);其肝功能酶学指标在术后1、3d明显升高,组织学见肝细胞核分裂极其活跃。结论冷缺血1h的30%供肝和肝切除后肝脏具有同样的增殖活性,仅增殖高峰稍晚;较短的冷缺血时间以及熟练的手术技术可能对小体积供肝的再生起重要作用。 | 何清 陈燕涛 张红卫 谷艳丽 Uta Dahmen Olaf Dirsch 王捷 | 2005 | 岭南现代临床外科2005，5，3： | 1 |
| 7 | 冷缺血对大鼠小体积肝移植肝再生的影响显示文摘目的探讨冷缺血对大鼠小体积肝移植术后肝再生的影响。方法本组在2002年9月~2004年8月利用大鼠肝总量30%原位肝移植模型,实验分为肝总量70%肝切除组(C组)和冷缺血1、3、5h组(E1、E2、E3组),观察1w生存率及肝重量/受体原肝重量比值(EGW/RLW),并检测术后1、2、3、7d肝细胞增殖活性及肝组织学变化。结果E1组1w生存率及EGW/RLW分别达100%和95%,均明显高于E2、E3组(P均<0.05);E1、E2、E3组均于术后2d达到增殖高峰,其中E1组峰值显著高于E2、E3组(P<0.001),且与C组峰值无差异(P>0.05);组织学检查见E1组肝细胞核分裂明显活跃。结论冷缺血1h的小体积供肝和70%肝切除后肝脏具有同样的增殖活性,仅增殖高峰稍晚;冷缺血超过3h严重影响小体积供肝的再生能力和受者的存活率。 | 何清 陈燕涛 王捷 谷艳丽 Uta Dahmen Olaf Dirsch | 2006 | 岭南现代临床外科2006，6，3： | 0 |
| 8 | Does granulocyte-colony stimulating factor administration induce damage or repair response in schistosomiasis?显示文摘AIM:To introduce Granulocyte-colony stimulating factor (G-CSF) as a new therapeutic modality for schistosomiasis through stem cell mobilization,immunomodulation or fibrosis remodeling. METHODS:In this study,a 5 d course of human recombinant G-CSF (100 μg/kg sc) was applied to Schis-tosoma mansoni-infected mice at different stages of disease (5 d before infection as well as 3,5 and 7 wk post-infection). The animals were sacrificed at 10 d as well as 4,6 and 8 wk post infection. Mice were examined for:(1) Total leukocyte count which is an accepted surrogate marker for the stem cell mobilization into the circulation; (2) Egg count in intestine and liver tissue to assess the parasitic load; and (3) Histopathological changes in Hx/E and Masson trichrome stained sections as well as collagen content in Sirius redstained liver sections to determine the severity of liver fibrosis. RESULTS:Mice developed leukocytosis. The egg load and the number of granulomas were not affected by the G-CSF treatment but there was an obvious change in the composition of granulomas towards an increased cellularity. Moreover,fibrosis was significantly decreased in treated groups compared to untreated animals (collagen content either preinfection or at 3 and 5 wk post infection:5.8 ± 0.5,4.7 ± 0.5,4.0 ± 0.7 vs 8.2 ± 0.9; P ≤ 0.01). CONCLUSION:Although G-CSF did not cause direct elimination of the parasite,it enhanced granulomatous reaction and reduced the fibrosis. Further investigation of the underlying mechanisms of these two actions is warranted. | Lobna Y Ghanem Uta Dahmen Olaf Dirsch Mona MF Nosseir Soheir S Mahmoud Wafaa AF Mansour | 2010 | World Journal of Hepatology2010，2，12： | 0 |
| 9 | Administration of granulocyte colony stimulating factor after liver transplantation leads to an increased incidence and severity of ischemic biliary lesions in the rat model显示文摘瞄准:最近,粒细胞殖民地刺激因素(G-CSF ) 罐头在健康骨髓施主导致 hypercoagulability,这被报导了。prothrombotic 的正式就职与已经损害的灌注在机关接枝的一个接受者声明原因可能在移植机关推进恶化,是想得到的。这研究评估了 G-CSF 治疗是否变得更坏在老鼠的肝灌注追随者肝移植当模特儿。方法:一个化为动脉血得非的老鼠肝移植模特儿被雇用在 syngeneic 和 allogeneic 紧张联合在肝上评估 G-CSF 治疗的效果。学习结果包括了由肝酶和肝组织学调查了的生存时间和肝损坏。观察时间是 1 d, 1 wk 和 12 wk。结果:与 G-CSF 对待的老鼠增加了胆汁的损坏追随者肝移植的发生和严厉。在这些动物,肝细胞坏死在小叶中心区域被加重。这些损害在 G-CSF 的损害灌注是指示的对待的动物。结论:当治疗可能提高先存在的、未被发现的灌注问题并且最终导致局部缺血, G-CSF 应该在肝移植的接受者小心地被使用导致的胆汁的复杂并发症。 | Olaf Dirsch Haidong Chi Yuan Ji Yan Li Gu Christoph E Broelsch Uta Dahmen | 2006 | World Journal of Gastroenterology2006，12，31： | 0 |
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