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1篇 您的检索式:作者名="Oluwasegun Modupe"
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1Optimization of unit operations for microencapsulating ferrous fumarate during scale-up of double fortification of salt with iron and iodine显示文摘Objectives:This study evaluates factors responsible for the floating of iron premix in double fortified salt(DFS),which initially affected the large-scale implementation of the salt fortification program in India,and provides solutions to the scale-up of the technology.Materials and Methods:To mitigate this time-sensitive scale-up challenge.First,the iron premix samples were obtained from the industrial scale-up pilot studies in India,evaluated for the impact of the amount of coating material(5 per cent,7.5 per cent,and 10 per cent(in weight)),type of formulation(soy stearin,SEPIFILM and hydroxypropyl methylcellulose),amount of titanium dioxide(25-35 per cent(in weight))used for color masking;Second,we studied the effect of change in the composition of the coating,from 10 per cent(in weight)soy stearin to a double coat with 5 per cent(in weight)hydroxypropyl methylcellulose and 5 per cent soy stearin or 10 per cent soy stearin and 1 per cent(in weight)lecithin mixture,on particle density,floating or sinking property of the iron premix,and on the stability of iodine in the DFS.Results:It was observed that the hydrophobic nature and the amount of soy stearin used for coating caused the floating issue.The double coating with 5 per cent hydroxypropyl methylcellulose and 5 per cent soy stearin was preferred because lecithin in soy stearin enhanced the moisture-aided adverse interaction between iron and iodine.Shelf-life storage studies proved over 80 per cent iodine retention after 12 months of storage in the DFS formulated with iron premix double-coated with hydroxypropyl methylcellulose and soy stearin.Conclusion:This proffered solution enabled the full implementation of the double fortification program in India.Oluwasegun Modupe Kiruba Krishnaswamy Yao Olive Li Levente L.Diosady 2021Food Quality and Safety2021,5,4:0
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