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| 1 | Achieving the best bowel preparation for colonoscopy显示文摘Bowel preparation is a core issue in colonoscopy,as it is closely related to the quality of the procedure.Patients often find that bowel preparation is the most unpleasant part of the examination.It is widely accepted that the quality of cleansing must be excellent to facilitate detecting neoplastic lesions.In spite of its importance and potential implications,until recently,bowel preparation has not been the subject of much study.The most commonly used agents are high-volume polyethylene glycol(PEG)electrolyte solution and sodium phosphate.There has been some confusion,even in published meta-analyses,regarding which of the two agents provides better cleansing.It is clear now that both PEG and sodium phosphate are effectivewhen administered with proper timing.Consequently,the timing of administration is recognized as one of the central factors to the quality of cleansing.The bowel preparation agent should be administered,at least in part,a few hours in advance of the colonoscopy.Several low volume agents are available,and either new or modified schedules with PEG that usually improve tolerance.Certain adjuvants can also be used to reduce the volume of PEG,or to improve the efficacy of other agents.Other factors apart from the choice of agent can improve the quality of bowel cleansing.For instance,the effect of diet before colonoscopy has not been completely clarified,but an exclusively liquid diet is probably not required,and a low-fiber diet may be preferable because it improves patient satisfaction and the quality of the procedure.Some patients,such as diabetics and persons with heart or kidney disease,require modified procedures and certain precautions.Bowel preparation for pediatric patients is also reviewed here.In such cases,PEG remains the most commonly used agent.As detecting neoplasia is not the main objective with these patients,less intensive preparation may suffice.Special considerations must be made for patients with inflammatory bowel disease,including safety and diagnostic issues,so that the most adequate agent is chosen.Identifying neoplasia is one of the main objectives of colonoscopy with these patients,and the target lesions are often almost invisible with white light endoscopy.Therefore excellent quality preparation is required to find these lesions and to apply advanced methods such as chromoendoscopy.Bowel preparation for patients with lower gastrointestinal bleeding represents a challenge,and the strategies available are also reviewed here. | Adolfo Parra-Blanco Alex Ruiz Manuel Alvarez-Lobos Ana Amorós Juan Cristóbal Gana Patricio Ibáez Akiko Ono Takahiro Fujii | 2014 | World Journal of Gastroenterology2014，20，47： | 37 |
| 2 | Modified boron neutron capture therapy for malignant gliomas performed using epithermal neutron and two boron compounds with different accumulation mechanisms: an efficacy study based on findings on neuroimages显示文摘 | Miyatake S Kawabata S Kafimoto Y Aoki A Yokoyama K Yamada M Kuroiwa T Tsuji M Imahori Y Kirihata M Sakurai Y Masunaga S Nagata K Maruhashi A Ono K | 2005 | 中国神经肿瘤杂志2005，3，4： | 14 |
| 3 | Concordance of non-invasive mechanical and serum tests for liver fibrosis evaluation in chronic hepatitis C显示文摘AIM To determine the sensitivity and specificity of liver stiffness measurement(LSM) and serum markers(SM) for liver fibrosis evaluation in chronic hepatitis C.METHODS Between 2012 and 2014,81 consecutive hepatitis C virus(HCV) patients had METAVIR score from liver biopsy compared with concurrent results from LSM [transient elastography(TE) [FibroS can~/ARFI technology(Virtual Touch~)] and SM [FIB-4/aspartate aminotransferase-toplatelet ratio index(APRI)].The diagnostic performance of these tests was assessed using receiver operating characteristic curves.The optimal cut-off levels of each test were chosen to define fibrosis stages F ≥ 2,F ≥ 3 and F = 4.The Kappa index set the concordance analysis.RESULTS Fifty point six percent were female and the median age was 51 years(30-78).Fifty-six patients(70%) weretreatment-na?ve.The optimal cut-off values for predicting F ≥ 2 stage fibrosis assessed by TE were 6.6 kP a,for acoustic radiation force impulse(ARFI) 1.22 m/s,for APRI 0.75 and for FIB-4 1.47.For F ≥ 3 TE was 8.9 kP a,ARFI was 1.48 m/s,APRI was 0.75,and FIB-4 was 2.For F = 4,TE was 12.2 kP a,ARFI was 1.77 m/s,APRI was 1.46,and FIB-4 was 3.91.The APRI could not distinguish between F2 and F3,P = 0.92.The negative predictive value for F = 4 for TE and ARFI was 100%.Kappa index values for F ≥ 3 METAVIR score for TE,ARFI and FIB-4 were 0.687,0.606 and 0.654,respectively.This demonstrates strong concordance between all three screening methods,and moderate to strong concordance between them and APRI(Kappa index = 0.507).CONCLUSION Given the costs and accessibility of LSM methods,and the similarity with the outcomes of SM,we suggest that FIB-4 as well as TE and ARFI may be useful indicators of the degree of liver fibrosis.This is of particular importance to developing countries. | Denise C Paranaguá-Vezozzo Adriana Andrade Daniel F C Mazo Vinicius Nunes Ana L Guedes Taisa G Ragazzo Renata Moutinho Lucas S Nacif Suzane K Ono Venancio A F Alves Flair J Carrilho | 2017 | World Journal of Hepatology2017，9，8： | 7 |
| 4 | Improvement of the adhesion of the resin to the metal surface by using plasma jet显示文摘 | S Chen S Ono S Teii | 1997 | Surface and coatings technology1997，97，： | 1 |
| 5 | The pathogenesis of the systemic inflammatory response syndrome and compensatory antiinflammatory response syndrome following surgical stress 显示文摘 | Ono S Icgikura T Mochizuki H | 2003 | Nippon Geka Gakkai Zasshi2003，104，9： | 1 |
| 6 | Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors:it is independence of p53 status显示文摘 | Masunaga S Ono K Takahashi A | 2003 | Cancer Sci2003，94，1： | 1 |
| 7 | J Power Sources显示文摘 | Matsuoka O Hiwara A Omi T Toriida M Hayashi T Tanaka C Saito Y Ishida T Tan H Ono S S Yamamoto S | 2002 | 108:1282002，108，： | 1 |
| 8 | Japan's superconducting maglev train显示文摘 | Ono M Koga S Ohtsuki H | 2002 | Instrumentation & Measurement Magazine IEEE2002，5，1： | 1 |
| 9 | Pathology of ossification of the posterior tongitudind and ligamentum flavum显示文摘 | Ono k Yonenobu K Miyamoto S | 1999 | Clin Orthop1999，359，： | 1 |
| 10 | High-dose interferon-alpha therapy lowers the levels of serum fibrogenesis markers over 5 years in chronic hepatitis C显示文摘 | ABE S TABARU A ONO M | 2003 | Hepatol Res2003，25，： | 1 |
| 11 | Augmentation in chemosensitivity of intratumor quies- cent cells by combined treatment with nicotinamide and mild hyperthermia显示文摘 | MASUNAGA S ONO K AKABOSHI M | 1997 | Jpn J Cancer Res1997，88，8： | 1 |
| 12 | Characterization of lithium niobate thin films dervied from aqueous solution显示文摘 | Ono' s Bose O Unger W | 1998 | J Am Ceram Soc1998，81，： | 1 |
| 13 | Theoretical and experimental evidence for a post perovskite phase of MgSiO3 in the Earth s D″ layer 显示文摘 | OGANOV A R ONO S | 2004 | Nature2004，430，： | 1 |
| 14 | Enantioselective synthesis of the lactone moiety of HMG-CoA reductase inhibitors:stereoselective synthesis of (+) - (4R,6R) -4-hydroxy-6- (2-phenylethyl) -tetrahydro-2H-pyran-2-one 显示文摘 | Honda T Ono S Mizutani H | 1997 | Tetrahedron:Asym- metry1997，8，： | 1 |
| 15 | Polarization mode dispersion influence in optical transmission systems显示文摘 | Ono T Yamazki S Shimizu H | 1994 | J Lightwave Technol1994，12，5： | 1 |
| 16 | Self-ordering of cell arrangement of anodic porous alumina formed in sulfuric acid solution显示文摘 | Masuda H Hasegwa F Ono S | 1997 | Journal of Electrochemical Society1997，144，5： | 1 |
| 17 | Prosthetic replacement stagery for cervical spine metastasis显示文摘 | Ono K Yonenobu K Ebara S | 1988 | Spine1988，13，7： | 1 |
| 18 | Efleet of deformation temperature on Hall-Petch relationship registered for polycrystalline magnesium显示文摘 | ONO N NOWAK R MIURA S | 2003 | Mater Lett2003，58，： | 1 |
| 19 | Clinical useful- ness of determining the rate of thermal clearance within heated tumors显示文摘 | Masunaga S Ono K Mitsumori M | 1996 | Jpn J Clin Oncol1996，26，6： | 1 |
| 20 | Flexible bronchofiberscope显示文摘 | Ikeda S Tsuboi E Ono R | 2010 | Jpn J Clin Oncol2010，40，9： | 1 |
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