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| 1 | Effect of diminazene aceturate,levamisole and vitamin C combination therapy in rats experimentally infected with Trypanosoma brucei brucei显示文摘Objective:To investigate the effect of diminazene aceturale(DA) alone or in combination with either levamisole and/or Vitamin C in albino rats experimentally infected with Trypanosoma brucei brucei.Methods:Thirty adult male albino rats,randomly assigned into 6 groups(A—F) of 5rats each were used.They were either infected with 1×10~a trypanosomes intraperitoneally(groups A-E) or uninfected(group F).The different groups were treated respectively as follows:group A-with 3.5 mg/kg DA;group B-3.5 mg/kg DA and 7.5 mg/kg levamisole;group C-3.S mg/kg DA and 100 mg/kg vitamin C;and group D-3.S mg/kg DA and 7.S mg/kg levamisole and 100 mg/kg vitamin C.Croup E was left untreated.Parameters assessed include:rectal temperature,body weight changes,packed cell volume(PCV),Haemoglobin concentration(Hb),total leucocyte count(TLC) differential leucocyte count(DLC),parasitaemia,clinical signs and survivability.Results:Average pre-patent period of 5 days was recorded.Parasites in the blood were cleared in all treated groups(A-D) within 48 hours post treatment(PT).Untreated rats in group E died between25 and 32 days post infection(PI).Relapse was not recorded in all the treated groups(A-D).The initial reduction in PCV,Hb,TLC and increases in rectal temperature following infection were reversed by the treatments.The rats that received drug combinations(groups B,C and D)showed faster and higher recovery rates than the uninfected control and group A.Conclusions:Levamisole and/or Vitamin C combination with DA were more effective in the treatment of rats infected with Trypanosoma brucei brucei. | Adieme Ijeoma Chekwube Ezeh Ikenna Onyema Ugochukwu Emmanuel Ikenna Romanus Chukwuduruo Ezeokonkwo | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，6： | 3 |
| 2 | 仲裁裁决在撒哈拉以南非洲的执行 | Emilia Onyema 朱伟东(译) | 2011 | 仲裁研究2011，，1： | 2 |
| 3 | Circulating heat shock protein 70 in health, aging and disease 显示文摘 | Njemini R Bautmans I Onyema O O | 2011 | BMC Immunol2011，12，： | 1 |
| 4 | Circulating heat shock pro- tein 70 in health, aging and disease 显示文摘 | Njemini R Bautmans I Onyema OO | 2011 | BMC Immunol2011，12，6： | 1 |
| 5 | Accurate preoperative diagnosis of ovarian pregnancy with transvaginal scan显示文摘 | Gupta N Gupta A Onyema G | 2012 | Case Rep Obstet Gynecol2012，2012，： | 1 |
| 6 | Class Ⅱ HDAC inhibition hampers hepatic stellate cell activation by induction of microRNA-29显示文摘 | Mannaerts I Eysackers N Onyema OO | | 0，，1： | 1 |
| 7 | Prevalence of depressive symptoms a- mong Nigerian medical undergraduates 显示文摘 | Aniebue PN Onyema GO | 2008 | Tvp Doct2008，38，3： | 1 |
| 8 | ClassⅡHDAC inhibition hampers hepatic stellate cell activation by induction of microRNA-29显示文摘 | Mannaerts I Eysackers N Onyema OO Van Beneden K Valente S Mai A | 2013 | PLo S One2013，8，55： | 1 |
| 9 | Chemotherapy-induced changes and immunosenescence of CD8 ^+ T-cells in patients with breast cancer显示文摘 | Onyema OO Decoster L Njemini R | 2015 | Anticancer Res2015，35，3： | 1 |
| 10 | ClassⅡ HDAC inhibition hampers hepatic stellate cell activation by induction of microRNA-29 显示文摘 | Mannaerts I Eysackers N Onyema OO | 2013 | PLoS One2013，8，55： | 1 |
| 11 | Class II HDACinhibition hampers hepatic stellate cell activation by induction of microRNA-29 显示文摘 | Mannaerts I Eysackers N Onyema O O | 2013 | PloS One2013，8，55： | 1 |
| 12 | Shortcomings in the application of multicolour flow cytometry in lymphocyte subsets enumeration显示文摘 | NJEMINI R ONYEMA OO RENMANS W | 2014 | Scand J Immunol2014，79，2： | 1 |
| 13 | Hybrid XGBoost model with hyperparameter tuning for prediction of liver disease with better accuracy显示文摘BACKGROUND Liver disease indicates any pathology that can harm or destroy the liver or prevent it from normal functioning.The global community has recently witnessed an increase in the mortality rate due to liver disease.This could be attributed to many factors,among which are human habits,awareness issues,poor healthcare,and late detection.To curb the growing threats from liver disease,early detection is critical to help reduce the risks and improve treatment outcome.Emerging technologies such as machine learning,as shown in this study,could be deployed to assist in enhancing its prediction and treatment.AIM To present a more efficient system for timely prediction of liver disease using a hybrid eXtreme Gradient Boosting model with hyperparameter tuning with a view to assist in early detection,diagnosis,and reduction of risks and mortality associated with the disease.METHODS The dataset used in this study consisted of 416 people with liver problems and 167 with no such history.The data were collected from the state of Andhra Pradesh,India,through http://gffzz32f81fe4765d4826svu5k6ofwpb9b6bcq.ffgz.tsg.suse.edu.cn/datasets/uciml/indian-liver-patientrecords.The population was divided into two sets depending on the disease state of the patient.This binary information was recorded in the attribute'is_patient'.RESULTS The results indicated that the chi-square automated interaction detection and classification and regression trees models achieved an accuracy level of 71.36%and 73.24%,respectively,which was much better than the conventional method.The proposed solution would assist patients and physicians in tackling the problem of liver disease and ensuring that cases are detected early to prevent it from developing into cirrhosis(scarring)and to enhance the survival of patients.The study showed the potential of machine learning in health care,especially as it concerns disease prediction and monitoring.CONCLUSION This study contributed to the knowledge of machine learning application to health and to the efforts toward combating the problem of liver disease.However,relevant authorities have to invest more into machine learning research and other health technologies to maximize their potential. | Surjeet Dalal Edeh Michael Onyema Amit Malik | 2022 | World Journal of Gastroenterology2022，28，46： | 0 |
| 14 | Religious Education in Authentic Human Development: A Theological-Ethical Consideration显示文摘From a theological ethical moral view,it seems obvious that adequate religious moral education is a sine qua non for authentic human development necessary for a solid nation-building.Although,state and religion are separated from each other,this should not imply a total dichotomy of religious influence on socio-political matters.A pure secularised world that has nothing to do with God,a society devoid of any form of religious affiliation,a society purely human having neither to do with God nor the spirits,such a society seems inconceivable and unrealistic and may not even be human.Experience shows that to be human demands some form of acknowledgment of a superior being,whose influence may inform one’s basic choices.The nature of the human person shows that there is nothing of the material that does not take its bearing from the religious-spiritual disposition of the person.Experience also confirms that a good moral life or virtuous life draws faith.St James the apostle implies this,when he says faith without good works or good moral life is dead(James 2:18).This can also be applicable to Abraham who is judged righteous because of his faith in God,i.e.,because he obeyed God’s command.Without faith,it is impossible to do God’s will,i.e.live a good moral life(Hebr 11:6).On the other hand,there are many forms of development,for instance:economic development,agricultural development,scientific,rural or urban development,which narrow into the human development that seems to determine their level.However,to have a solid sustainable development demands an adequate religious-moral education of the people,which functions both in the informal and formal forms of education.In as much as religious moral education gives solid grounding for adequate formation of the human person,the end result,and the development of the human person should at the same time reflect the national development.Development thus understood is holistic embracing the good of the individual as well as the nation.This article argues that authentic human development that may produce a national development worthy of the name draws from adequate religious moral education imparted on the citizens.It shows also that a worthy national development is a fore test of the development of the citizens of that nation,which in turn indicates their commitment to the common good.It is through the application of the common good that individuals reach their desired goals and so be able to contribute to the enrichment of the nation.This article suggests that good moral life is the manifestation of virtue learnt and practiced,which leads to adequate human development that eventually brings about solid national development.This type of development can be compared to what Pope Benedict XVI calls true social development,which respects the dignity of the all human beings. | Fr.Anozie Onyema | 2022 | Cultural and Religious Studies2022，10，1： | 0 |
| 15 | International Common Good in the Light of Gaudium ET Spes 26&74:A Moral Theological Study显示文摘When we talk about international issues,the meaning is pretty clear-issues concerning nations across-board.In this we wish to look at the issue of common good across nations.May be one could ask if there is any“Good”that is internationally common.The answer may seem obvious but a deeper look reveals something different,hence this article.In the same vein,the adage that“what is good for the goose is also good for the gander”sounds too theoretical to be real.In practical terms,experience shows that most people never enjoy what others lavishly expend.Some people wish themselves the pleasure of seeing the four walls of a school even late in their age,while some people graduate at an unimaginable young age.In this article:Common good across borders…;we argue that the good prevalent in the developed nations should be made available to the developing nations as well.This does not mean a conformism,but a uniformity in diversity.The salvation of the human person for St.Athanasius does not concern only the soul but the whole of the human person,i.e.,body and soul;this includes all human beings of any nationality.Analogically,the good of the human person embraces not just particular people,a chosen group,a hybrid but the entire humanity.One is able to strive forward in the face of difficulties if one sees oneself as part of a global community.Concretely,it entails leaders seek the good not just of the members of their particular nations,but also of members of other nations.The leaders of nations that do not adequately care for the global good of others would be very deficient,ineffective,and characterised as incompetent.In the same vein any individual,who clings to his or her particular nation or autonomy or seeks only one’s well-being without adequate reference to the global community or the macro group is surely on the false direction.Such a person is selfish and may sooner or later discover that without the macro-community,one’s reference point though the micro community would eventually not succeed adequately and may not fundamentally reach the self-fulfilment one desires. | Anozie Onyema | 2021 | Cultural and Religious Studies2021，9，11： | 0 |
| 16 | Impact of Mobile Technology and Use of Big Data in Physics Education During Coronavirus Lockdown显示文摘The speed of spread of Coronavirus Disease 2019 led to global lockdowns and disruptions in the academic sector.The study examined the impact of mobile technology on physics education during lockdowns.Data were collected through an online survey and later evaluated using regression tools,frequency,and an analysis of variance(ANOVA).The findings revealed that the usage of mobile technology had statistically significant effects on physics instructors’and students’academics during the coronavirus lockdown.Most of the participants admitted that the use of mobile technologies such as smartphones,laptops,PDAs,Zoom,mobile apps,etc.were very useful and helpful for continued education amid the pandemic restrictions.Online teaching is very effective during lock-down with smartphones and laptops on different platforms.The paper brings the limelight to the growing power of mobile technology solutions in physics education. | Edeh Michael Onyema Rijwan Khan Nwafor Chika Eucheria Tribhuwan Kumar | 2023 | Big Data Mining and Analytics2023，6，3： | 0 |
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