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| 1 | Enhancement of Antitumor Effect of Tegafur/Uracil(UFT) plus Leucovorin by Combined Treatment with Protein-Bound Polysaccharide,PSK,in Mouse Models显示文摘We evaluated the antitumor effect of combined therapy with tegafur/uracil(UFT) plus leucovorin(LV) (UFT/LV) and protein-bound polysaccharide,PSK,in three mouse models of transplantable tumors. UFT/LV showed antitumor effect against Meth A sarcoma,and the antitumor effect was enhanced when PSK given concomitantly. UFT/LV showed antitumor effect to Lewis lung carcinoma and PSK alone also showed antitumor effect at high dose,but a combination of UFT/LV and PSK resulted in no enhanced antitumor effect. Colon 26 carcinoma was weakly responsive to UFT/LV,and no enhancement of antitumor effect was found even PSK was used in combination. In conclusion,while the effect of PSK varies depending on tumor,combined use of UFT/LV and PSK may be expected to augment the antitumor effect. | Ryoji Katoh Mitsuru Ooshiro | 2007 | Cellular & Molecular Immunology2007，4，4： | 3 |
| 2 | Sporadic gastric carcinoid tumor successfully treated by two-stage laparoscopic surgery:A case report显示文摘We report a case of sporadic gastric carcinoid tumor successfully treated by two-stage laparoscopic surgery.A 38-year old asymptomatic woman was referred to our hospital for evaluation of a submucosal tumor of the stomach.Endoscopic examination showed a solitary submucosal tumor without ulceration or central depression on the posterior wall of the antrum and biopsy specimens were not sufficient to determine the diagnosis.Endoscopic ultrasound revealed a tumor nearly 2 cm in diameter arising from the muscle layer and a computed tomography scan showed the tumor enhanced in the arterial phase.Laparoscopic wedge resection was performed for definitive diagnosis.Pathologically,the tumor was shown to be gastric carcinoid infiltrating the muscle layer which indicated the probability of lymph node metastasis.Serum gastrin levels were normal.As a radical treatment,laparoscopy-assisted distal gastrectomy with regional lymphadenectomy was performed 3 wk after the initial surgery.Finally,pathological examination revealed no lymph node metastasis. | Takahiro Kinoshita Takashi Oshiro Tasuku Urita Yutaka Yoshida Mitsuru Ooshiro Shinichi Okazumi Ryoji Katoh Daisuke Sasai Nobuyuki Hiruta | 2010 | World Journal of Gastrointestinal Surgery2010，2，11： | 2 |
| 3 | Fourniers gangrene progressing from the buttocks to the scrotum following a perianal abscess 显示文摘 | Sugishita Y Nagashima M Ooshiro M | 2008 | J Infect Chemother2008，14，1： | 1 |
| 4 | Primary culture of freshly isolated liver cell ofthe eel显示文摘 | HAYASHI S OOSHIRO Z | 1985 | Bull Jap Soc Sci Fish1985，51，： | 1 |
| 5 | Fourniers gangrene progressing from the buttocks to the scrotum following a perianal abscess显示文摘 | Yui Sugishita Makoto Nagashima Mitsuru Ooshiro | 2009 | Journal of Infection and Chemotherapy2009，10，1： | 1 |
| 6 | Characteristicsof Ralstonia solanacearum biovar N2 strains in Asia 显示文摘 | HORITA M TSUCHIYA K OOSHIRO A | 2005 | Journal of Phytopathology2005，153，4： | 1 |
| 7 | Regulation of perioperative immunological changes following laparotomy : effects of biological response modifier (BRM) on surgical stress 显示文摘 | Ooshiro M Sugishita YI Tanaka H | 2004 | Immunol Lett2004，93，1： | 1 |
| 8 | Research on Generation of Three-Dimensional Surface with Micro-Electrolyte Jet Ma- chining显示文摘 | Natsu W Ooshiro S Kunieda M | 2008 | CIRP Journal of Manufacturing Science and Technology2008，1，1： | 1 |
| 9 | Detection of Anaplasma boris and Anaplasma phagocytophilum from cattle on Yonaguni Island,Okinawa Japan显示文摘 | OOSHIRO M ZAKIMI S MATSUKAWA Y | 2008 | Vet Parasitol2008，154，： | 1 |
| 10 | Expression of C-terminal truncated and full-length Babesia bigemina rhoptry-associated protein 1 and their potential use in enzyme-linked immunosorbent assay显示文摘 | Suthisak Boonchit Andy Alhassan Bun Chan Xuenan Xuan Naoaki Yokoyama Mamoru Ooshiro Will L. Goff Suryakant D. Waghela Gale Wagner Ikuo Igarashi | 2006 | Veterinary Parasitology2006，，1： | 1 |
| 11 | Primary culture of the eel hepatocytes in the serum-free medium显示文摘 | Hayashi S Ooshiro Z | 1986 | Bulletin of the Japanese Society of Scientific Fisheries1986，52，9： | 1 |
| 12 | Primary culture of the freshly isolated liver cells of the eel显示文摘 | Hayashi S Ooshiro Z | 1985 | Bull Japan Soc Sci Fish1985，51，： | 1 |
| 13 | Copper-free Sonogashira coupling in water with an amphiphilic resin-supported palladium complex显示文摘 | Suzuka T Okada Y Ooshiro K | 2010 | Tetrahedron2010，66，5： | 1 |
| 14 | Detection of Anaplasma boris and Anaplasma phagocytophilum from cattle on Yonaguni Island, Okinawa,Japan显示文摘 | OOSHIRO M ZAKIMI S MATSUKAWA Y etal | 2008 | Vet Parasitol2008，154，34： | 1 |
| 15 | Negative inotropic effect of diazepam in isolated guinea pig heart 显示文摘 | HARA Y KOBAYASHI H OOSHIRO S | 2001 | J Vet Med Sci2001，63，2： | 1 |
| 16 | Fournier's gangrene progressing from the buttocks to the scrotum fol- lowing a perianal abscess显示文摘 | Sugishita Y Nagashima M Ooshiro M | 2008 | J Infect Chemother2008，14，1： | 1 |
| 17 | Analysis of genetic and biological characters of Japanase potato strains of Ralstonia solanacearum显示文摘 | HORITA M SUGA Y OOSHIRO A | 2010 | J Gen Plant Pathol2010，76，： | 1 |
| 18 | Research on generation of three-dimensional surface with micro-electrolyte jet machining显示文摘 | Natsu W Ooshiro S Kunieda M | 2008 | CIRP Journal of Manufacturing Science and Technology2008，1，1： | 1 |
| 19 | Primary culture of freshly isolated liver cell of the eel显示文摘 | Hayashi S Ooshiro Z | 1985 | Bull Jpn Soc Sci Fish1985，51，： | 1 |
| 20 | Circuit simulation models for coming MOSFET generations 显示文摘 | Mitiko Miura-Mattausch Seiwa Ooshiro Masami Suetake | 2000 | Simulation of Smiconductor Processes and Devices2000，，： | 1 |
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