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| 1 | Prognosis of hepatocellular carcinoma accompanied by microscopic portal vein invasion显示文摘AIM:To investigate the prognostic factors in patients with hepatocellular carcinoma(HCC) accompanied by microscopic portal vein invasion(PVI).METHODS:Of the 267 patients with HCC undergoing hepatic resection at Aso Iizuka Hospital,71 had PVI.After excluding 16 patients with HCC that invaded the main trunk and the first and second branches of the portal vein,55 patients with microscopic PVI were enrolled.RESULTS:The patients with HCC accompanied by microscopic invasion were divided into two groups:solitary PVI(PVI-S:n = 44),and multiple PVIs(PVI-M:n = 11).The number of portal vein branches invaded by tumor thrombi was 5.4 ± 3.8(2-16) in patients with PVI-M.In cumulative survival,PVI-M was found to be a significantly poor prognostic factor(P = 0.0019);while PVI-M and non-anatomical resection were significantly poor prognostic factors in disease-free survival(P = 0.0213,and 0.0115,respectively).In patients with PVI-M,multiple intrahepatic recurrence was more common than in the patients with PVI-S(P = 0.0049).In patients with PVI-S,non-anatomical resection was a significantly poor prognostic factor in disease-free survival(P = 0.0370).Operative procedure was not a significant prognostic factor in patients with PVI-M.CONCLUSION:The presence of PVI-M was a poor prognostic factor in patients with HCC,accompanied by microscopic PVI.Anatomical resection is recommended in these patients with HCC.Patients with HCC and PVI-M may also be good candidates for adjuvant chemotherapy. | Ken Shirabe Kiyoshi Kajiyama Norifumi Harimoto Hideaki Masumoto Tatsuro Fukuya Masafumi Ooya Yoshihiko Maehara | 2009 | World Journal of Gastroenterology2009，15，21： | 10 |
| 2 | A clinical long-term radiographic evaluation of graft height changes after maxillary sinus floor augmentation with a 2:1 autogenous bone/xenograft mixture and simultaneous placement of dental implants显示文摘 | Hatano N Shimizu Y Ooya K | 2004 | Clin Oral Implants Res2004，15，3： | 1 |
| 3 | Expression of inducible nitric oxide synthase and heat shock proteins in periapical inflammatory lesions显示文摘 | Suzuki T Kumamoto H Ooya K | 2002 | J Oral Pathol Med2002，31，： | 1 |
| 4 | Effects of ethylene glycol-based graft,star-shaped,and dendritic polymers on solubilization and controlled release of paelitaxel 显示文摘 | Ooya T Lee J Park K | 2003 | J Controlled Release2003，93，12： | 1 |
| 5 | Glucosylation of phenolic compounds by plant cell cultures 显示文摘 | Tabata M Umetani Y Ooya M | 1988 | Phytochemistry1988，27，3： | 1 |
| 6 | Immunohistochemical detection of uPA,uPAR,PAI-1,and maspin in ameloblastic tumors显示文摘 | Kumamoto H Ooya K | 2007 | J Oral Pathol Med2007，36，8： | 1 |
| 7 | Thermally switchable polyrotaxane as a model of stimuli-responsive supramolecules for nano-scale devices 显示文摘 | Fujita H Ooya T Kurisawa M | 1996 | Macromolecular Rapid Communications1996，17，171： | 1 |
| 8 | Immunohistochemical detection of uPA, uPAR, PAI-1, and maspin in ameloblastic tumors 显示文摘 | Kumamoto H Ooya K | 2007 | J Oral Pathol Med2007，36，8： | 1 |
| 9 | Expression of p63 and p73 in ameloblastomas显示文摘 | Kumamoto H Ohki K Ooya K | 2005 | J Oral Pathol Med2005，34，4： | 1 |
| 10 | A clinical long-term radiographic evaluation of graft height changes after maxillary sinus floor aug- mentation with 2:1 autogenous bone/xenograft mixture and simul- taneous placement of dental implants显示文摘 | Hatano N Shimizu Y Ooya K | 2004 | Clin Oral Implants Res2004，15，3： | 1 |
| 11 | Muhivalent interactions between biotin- polyrotaxane conjugates and streptavidin as a model of new targeting for transporters显示文摘 | Ooya T Yui N | 2002 | Journal of Controlled Release2002，80，123： | 1 |
| 12 | Effects of added grain koji on the physical properties and palatability of sika deer meat product显示文摘 | Yoshimura A M Ooya H Fujimura T | 2011 | Journal of The Japanese Society for Food Science and Technology:Nippon Shokuhin Kagaku Kaishi2011，58，11： | 1 |
| 13 | Protein imprinted TiO2-coatedquantum dots for fluorescent protein sensing prepared by liq-uid phase deposition显示文摘 | Inoue J Ooya TtTakeuchi T | 2011 | Soft Matter2011，7，20： | 1 |
| 14 | Immunohistochemical detection of phosphorylated Akt,PI3K,and PTEN in ameloblastic tumors显示文摘 | Kumamoto H Ooya K | | 0，，05： | 1 |
| 15 | Immunohistochemical detection of MT1-MMP,RECK,and EMMPRIN in ameloblastic tumors显示文摘 | Kumamoto H Ooya K | 2006 | J Oral Pathol Med2006，35，6： | 1 |
| 16 | Expression of p63 and p73 in a melohl astomas 显示文摘 | Kumamoto H Ohki K Ooya K | 2005 | J Oral Pathol Med2005，34，4： | 1 |
| 17 | Controllable erosion time and profile in poly(ethylene glycol) hydrogels by supramolecular structure of hydrolyzable polyrotaxane显示文摘 | Ichi T Watanabe J Ooya T | 2001 | Biomacrornolecules2001，2，： | 1 |
| 18 | Hyaluronic acid grafted with poly(ethylene glycol) as a novel peptide formulation显示文摘 | Moriyama K Ooya T Yui N | 1999 | Journal Controlled Release1999，59，1： | 1 |
| 19 | Control of rapid phase transition induced by supramolecular complexation of α-cyclodextrin-conjugated poly (ε-lysine) with a specific guest显示文摘 | Choi H S Ooya T Sasaki S | 2003 | Macromolecules2003，36，14： | 1 |
| 20 | pH and thermosensitive supramolecular assembling system:rapidly responsive properties of β-cyclodextrin-conjugated poly(ε-lysine)显示文摘 | Choi H S Huh K M Ooya T | 2003 | Journal of the American Chemical Society2003，125，21： | 1 |
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