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| 1 | Integrative analysis of the human cis-antisense gene pairs,miRNAs and their transcription regulation patterns显示文摘 | Grinchuk OV Jenjaroenpun P Orlov YL | | 0,,: | 1 |
| 2 | Leptin induces rat glomerular mesangial cell hypertrophy,bu t does not regulate hyperplasia or apoptosis显示文摘 | LeeM P Orlov D Sweeney G | 2005 | Int J Obes (Lond)2005,29,: | 1 |
| 3 | Integrative analysis of the human cis-antisense gene pairs,miRNAs and their transcription regulation patterns显示文摘 | Grinchuk OV Jenjaroenpun P Orlov YL | 2010 | Nucleic Acids Res2010,38,2: | 1 |
| 4 | Fanout gate in quantum dot cellular automata 显示文摘 | YADAVALLI K K ORLOV A O TIMLER J P | 2007 | Nano- technology2007,18,37: | 1 |
| 5 | New approaches to synthesizing electroactive polymers 显示文摘 | Karpacheva G P Orlov A V Kiseleva S G | 2004 | Russian Journal of Electrochemistry2004,40,3: | 1 |
| 6 | Sheathless implan- tation of permanent coronary sinus-LV pacing leads显示文摘 | Hoffmeister P Chaudhry GM Orlov MV | 2006 | Pacing Clin Electrophysiol2006,29,2: | 1 |
| 7 | New approaches to synthesizing electroactive polymers显示文摘 | Karpacheva G P Orlov A V Kiseleva S G | 2004 | Russian Journal of Electrochemistry2004,40,3: | 1 |
| 8 | Potential radio- sensitizing agents显示文摘 | Sharnin G P Fassakhov R K Orlov P P | 1975 | Chem Abstu1975,82,15: | 1 |
| 9 | Magnetic immunoassay for detection of staphylococcal toxins in complex media显示文摘 | Orlov A V Khodakova J A Nikitin M P | 2012 | Analytical chemistry2012,85,2: | 1 |
| 10 | Adaptive identification of linear time-delay systems显示文摘 | Orlov Y Belkoura L Richard J P | 2003 | International Journal of Robust and Nonlinear Control2003,13,9: | 1 |
| 11 | Fanout gate in quantum-dot cellular automata 显示文摘 | YADAYALLI K K ORLOV A O TIMLER J P | 2007 | Nano- technology2007,18,37: | 1 |
| 12 | Disease modifying treatment of spinal cord injury with directly reprogrammed neural precursor cells in non-human primates显示文摘BACKGROUND The development of regenerative therapy for human spinal cord injury(SCI)is dramatically restricted by two main challenges:the need for a safe source of functionally active and reproducible neural stem cells and the need of adequate animal models for preclinical testing.Direct reprogramming of somatic cells into neuronal and glial precursors might be a promising solution to the first challenge.The use of non-human primates for preclinical studies exploring new treatment paradigms in SCI results in data with more translational relevance to human SCI.AIM To investigate the safety and efficacy of intraspinal transplantation of directly reprogrammed neural precursor cells(drNPCs).METHODS Seven non-human primates with verified complete thoracic SCI were divided into two groups:drNPC group(n=4)was subjected to intraspinal transplantation of 5 million drNPCs rostral and caudal to the lesion site 2 wk post injury,and lesion control(n=3)was injected identically with the equivalent volume of vehicle.RESULTS Follow-up for 12 wk revealed that animals in the drNPC group demonstrated a significant recovery of the paralyzed hindlimb as well as recovery of somatosensory evoked potential and motor evoked potential of injured pathways.Magnetic resonance diffusion tensor imaging data confirmed the intraspinal transplantation of drNPCs did not adversely affect the morphology of the central nervous system or cerebrospinal fluid circulation.Subsequent immunohistochemical analysis showed that drNPCs maintained SOX2 expression characteristic of multipotency in the transplanted spinal cord for at least 12 wk,migrating to areas of axon growth cones.CONCLUSION Our data demonstrated that drNPC transplantation was safe and contributed to improvement of spinal cord function after acute SCI,based on neurological status assessment and neurophysiological recovery within 12 wk after transplantation.The functional improvement described was not associated with neuronal differentiation of the allogeneic drNPCs.Instead,directed drNPCs migration to the areas of active growth cone formation may provide exosome and paracrine trophic support,thereby further supporting the regeneration processes. | Vladimir P Baklaushev Oleg V Durov Vladimir A Kalsin Eugene V Gulaev Sergey V Kim Ilya L Gubskiy Veronika A Revkova Ekaterina M Samoilova Pavel A Melnikov Dzhina D Karal-Ogly Sergey V Orlov Alexander V Troitskiy Vladimir P Chekhonin Alexander V Averyanov Jan-Eric Ahlfors | 2021 | World Journal of Stem Cells2021,13,5: | 1 |
| 13 | Triceratolepidophis sieversorum, a new genus and species of pitviper (Reptilia: Serpentes: Viperidae: Crotalinae) from Vietnam 显示文摘 | Ziegler T H W Herrmann P David N L Orlov and O S G Pauwels | 2000 | Russia Journal of Herpetology2000,7,: | 1 |
| 14 | On identifiability of linear time delay systems 显示文摘 | ORLOV Y BELKOURA L RICHARD J P | 2002 | IEEE Trans Automat Contr2002,47,8: | 1 |
| 15 | Apoptosis in cardiovascular re- modeling:Effect of medication 显示文摘 | deBlois D Orlov SN Hamet P | 2001 | Cardiovasc Drugs Ther2001,15,6: | 1 |
| 16 | Structure and gas separation properties of composite films based on polyaniline显示文摘 | Orlov A V Kiseleva S G Karpacheva G P | 2003 | J Appl Polym Sci2003,89,: | 1 |
| 17 | Pulsed electron-beam treat of WC-TiC-Co hard alloy cutting tools:wear resistance and microstructure evolution显示文摘 | IVANOV Y F ROTSHTEIN V P PROSKUROVSKY D I ORLOV P V POLESTCHENKO K N OZUR G E GONCHARENKO I M | 2000 | Surf Coat Tech2000,125,: | 1 |
| 18 | Integrative analysis of the human cis-antisense gene pairs,miRNAs and their transcription regulation patterns显示文摘 | Grinchuk OV Jenjaroenpun P Orlov YL | 2010 | Nucleic Acids Res2010,38,2: | 1 |