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18篇 您的检索式:作者名="Orlov P P"
    题名 作者 年代 出处 被引量
1Integrative analysis of the human cis-antisense gene pairs,miRNAs and their transcription regulation patterns显示文摘Grinchuk OV Jenjaroenpun P Orlov YL 0,,:1
2Leptin induces rat glomerular mesangial cell hypertrophy,bu t does not regulate hyperplasia or apoptosis显示文摘LeeM P Orlov D Sweeney G 2005Int J Obes (Lond)2005,29,:1
3Integrative analysis of the human cis-antisense gene pairs,miRNAs and their transcription regulation patterns显示文摘Grinchuk OV Jenjaroenpun P Orlov YL 2010Nucleic Acids Res2010,38,2:1
4Fanout gate in quantum dot cellular automata 显示文摘YADAVALLI K K ORLOV A O TIMLER J P 2007Nano- technology2007,18,37:1
5New approaches to synthesizing electroactive polymers 显示文摘Karpacheva G P Orlov A V Kiseleva S G 2004Russian Journal of Electrochemistry2004,40,3:1
6Sheathless implan- tation of permanent coronary sinus-LV pacing leads显示文摘Hoffmeister P Chaudhry GM Orlov MV 2006Pacing Clin Electrophysiol2006,29,2:1
7New approaches to synthesizing electroactive polymers显示文摘Karpacheva G P Orlov A V Kiseleva S G 2004Russian Journal of Electrochemistry2004,40,3:1
8Potential radio- sensitizing agents显示文摘Sharnin G P Fassakhov R K Orlov P P 1975Chem Abstu1975,82,15:1
9Magnetic immunoassay for detection of staphylococcal toxins in complex media显示文摘Orlov A V Khodakova J A Nikitin M P 2012Analytical chemistry2012,85,2:1
10Adaptive identification of linear time-delay systems显示文摘Orlov Y Belkoura L Richard J P 2003International Journal of Robust and Nonlinear Control2003,13,9:1
11Fanout gate in quantum-dot cellular automata 显示文摘YADAYALLI K K ORLOV A O TIMLER J P 2007Nano- technology2007,18,37:1
12Disease modifying treatment of spinal cord injury with directly reprogrammed neural precursor cells in non-human primates显示文摘BACKGROUND The development of regenerative therapy for human spinal cord injury(SCI)is dramatically restricted by two main challenges:the need for a safe source of functionally active and reproducible neural stem cells and the need of adequate animal models for preclinical testing.Direct reprogramming of somatic cells into neuronal and glial precursors might be a promising solution to the first challenge.The use of non-human primates for preclinical studies exploring new treatment paradigms in SCI results in data with more translational relevance to human SCI.AIM To investigate the safety and efficacy of intraspinal transplantation of directly reprogrammed neural precursor cells(drNPCs).METHODS Seven non-human primates with verified complete thoracic SCI were divided into two groups:drNPC group(n=4)was subjected to intraspinal transplantation of 5 million drNPCs rostral and caudal to the lesion site 2 wk post injury,and lesion control(n=3)was injected identically with the equivalent volume of vehicle.RESULTS Follow-up for 12 wk revealed that animals in the drNPC group demonstrated a significant recovery of the paralyzed hindlimb as well as recovery of somatosensory evoked potential and motor evoked potential of injured pathways.Magnetic resonance diffusion tensor imaging data confirmed the intraspinal transplantation of drNPCs did not adversely affect the morphology of the central nervous system or cerebrospinal fluid circulation.Subsequent immunohistochemical analysis showed that drNPCs maintained SOX2 expression characteristic of multipotency in the transplanted spinal cord for at least 12 wk,migrating to areas of axon growth cones.CONCLUSION Our data demonstrated that drNPC transplantation was safe and contributed to improvement of spinal cord function after acute SCI,based on neurological status assessment and neurophysiological recovery within 12 wk after transplantation.The functional improvement described was not associated with neuronal differentiation of the allogeneic drNPCs.Instead,directed drNPCs migration to the areas of active growth cone formation may provide exosome and paracrine trophic support,thereby further supporting the regeneration processes.Vladimir P Baklaushev Oleg V Durov Vladimir A Kalsin Eugene V Gulaev Sergey V Kim Ilya L Gubskiy Veronika A Revkova Ekaterina M Samoilova Pavel A Melnikov Dzhina D Karal-Ogly Sergey V Orlov Alexander V Troitskiy Vladimir P Chekhonin Alexander V Averyanov Jan-Eric Ahlfors 2021World Journal of Stem Cells2021,13,5:1
13Triceratolepidophis sieversorum, a new genus and species of pitviper (Reptilia: Serpentes: Viperidae: Crotalinae) from Vietnam 显示文摘Ziegler T H W Herrmann P David N L Orlov and O S G Pauwels 2000Russia Journal of Herpetology2000,7,:1
14On identifiability of linear time delay systems 显示文摘ORLOV Y BELKOURA L RICHARD J P 2002IEEE Trans Automat Contr2002,47,8:1
15Apoptosis in cardiovascular re- modeling:Effect of medication 显示文摘deBlois D Orlov SN Hamet P 2001Cardiovasc Drugs Ther2001,15,6:1
16Structure and gas separation properties of composite films based on polyaniline显示文摘Orlov A V Kiseleva S G Karpacheva G P 2003J Appl Polym Sci2003,89,:1
17Pulsed electron-beam treat of WC-TiC-Co hard alloy cutting tools:wear resistance and microstructure evolution显示文摘IVANOV Y F ROTSHTEIN V P PROSKUROVSKY D I ORLOV P V POLESTCHENKO K N OZUR G E GONCHARENKO I M 2000Surf Coat Tech2000,125,:1
18Integrative analysis of the human cis-antisense gene pairs,miRNAs and their transcription regulation patterns显示文摘Grinchuk OV Jenjaroenpun P Orlov YL 2010Nucleic Acids Res2010,38,2:1
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