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    题名 作者 年代 出处 被引量
1Role of autophagy in the pathophysiology of nonalcoholic fatty liver disease:A controversial issue显示文摘Autophagy is a mechanism involved in cellular homeostasis under basal and stressed conditions delivering cytoplasmic content to the lysosomes for degradation to macronutrients.The potential role of autophagy in disease is increasingly recognised and investigated in the last decade.Nowadays it is commonly accepted that autophagy plays a role in the hepatic lipid metabolism.Hence,dysfunction of autophagy may be an underlying cause of non-alcoholic fatty liver disease.However,controversy of the exact role of autophagy in the lipid metabolism exists:some publications report a lipolytic function of autophagy,whereas others claim a lipogenic function.This review aims to give an update of the present knowledge on autophagy in the hepatic lipid metabolism,hepatic insulin resistance,steatohepatitis and hepatic fibrogenesis.Wilhelmus J Kwanten Wim Martinet Peter P Michielsen Sven M Francque 2014World Journal of Gastroenterology2014,20,23:17
2Highly active, recyclable catalyst for the manufacture of viscous, low molecular weight, CO--ethene-propene-based polyketone, base component for a new class of resins显示文摘Wilhelmus P Mul Hendrik Dirkzwager Antonius A Broekhuis 2002Inorganica Chimica Acta2002,327,:1
3Wheredoes knowledge management and va!ue显示文摘CHONG C W T HOLDEN P WILHELMU 2000Journal of Intel-lectual Capital2000,1,4:1
4Collagen XVIII:A novel heparin sulfate proteoglycan associated with vascular amyloid deposi- tions and senile plaques in Alzheimer' s disease brains 显示文摘van Horssen J Wilhelmus MM Heljasvaara R Pihlajaniemi T Wesseling P de Waal RM 2002Brain Pathol2002,12,4:1
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