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| 1 | Nonionic surfactant vesicular systems for effective drug delivery—an overview显示文摘Vesicular systems are a novel means of drug delivery that can enhance bioavailability of encapsulated drug and provide therapeutic activity in a controlled manner for a prolonged period of time.Liposomes were the first such system but they suffer from a number of drawbacks including high cost and lack of stability at various pHs.Niosomes are a nonionic surfactant vesicular system,which can be easily and reliably made in the laboratory.Many factors affect noisome formation such as the method of manufacture,nature of surfactant and encapsulated drug,temperature at which the lipids are hydrated and the critical packing parameter.This review describes all aspects of niosomes including their different compositions,the various methods of preparation,the effect of changing manufacturing parameters,methods of characterization,factors that affect their stability,their use by various routes of administration,their therapeutic applications and the most important patents.The review also provides detailed information of the various types of niosomes that provide effective drug delivery. | Gannu P.Kumar Pogaku Rajeshwarrao | 2011 | Acta Pharmaceutica Sinica B2011，1，4： | 9 |
| 2 | Experimental studies and phase field modeling of microstructure evolution during solidification with electromagnetic stirring显示文摘Thixocasting requires manufacturing of billets with non-dendritic microstructure.Aluminum alloy A356 billets were produced by rheocasting in a mould placed inside a linear electromagnetic stirrer.Subsequent heat treatment was used to produce a transition from rosette to globular microstructure.The current and the duration of stirring were explored as control parameters.Simultaneous induction heating of the billet during stirring was quantified using experimentally determined thermal profiles.The effect of processing parameters on the dendrite fragmentation was discussed.Corresponding computational modeling of the process was performed using phase-field modeling of alloy solidification in order to gain insight into the process of morphological changes of a solid during this process.A non-isothermal alloy solidification model was used for simulations.The morphological evolution under such imposed thermal cycles was simulated and compared with experimentally determined one.Suitable scaling using the thermosolutal diffusion distances was used to overcome computational difficulties in quantitative comparison at system scale.The results were interpreted in the light of existing theories of microstructure refinement and globularisation. | P.GERALD TENNYSON P.KUMAR H.LAKSHMI G.PHANIKUMAR P.DUTTA | 2010 | 中国有色金属学会会刊:英文版2010，20，S3： | 8 |
| 3 | Effect of Tool Shoulder and Pin Probe Profiles on Friction Stirred Aluminum Welds-a Comparative Study显示文摘在海洋的申请,海洋的等级钢通常被使用为拖并且上层建筑。然而,铝也由于它的小质量成为了一种好选择,当铝生锈与钢相比是最小的时。在磨擦上在这糊研究促使铝合金焊接被介绍。现在的调查处理不同磨擦的效果促使在机械强度和铝合金焊接的微观结构性质上焊接工具几何学。有肩膀和工具探查侧面的不同类型的三不同工具几何学根据设计矩阵在调查被使用。焊接上的每个工具肩膀和探查几何学的效果被评估。磨擦搅动焊接工具几何学,这也被观察在焊接加强, microhardness,和焊接强度上有重要效果。 | H.K.Mohanty M.M.Mahapatra P.Kumar P.Biswas N.R.Mandal | 2012 | Journal of Marine Science and Application2012，11，2： | 5 |
| 4 | 装甲级Al-Zn-Mg合金搅拌摩擦焊接接头的力学性能(英文)显示文摘研究焊接速度和旋转速度对装甲级铝合金搅拌摩擦焊接接头的形成和力学性能的影响。采用弯曲试验、显微硬度测试、力学性能测试、光学显微镜和扫描电子显微镜对焊接接头进行表征。焊接接头的力学性能(包括显微硬度、抗拉强度和伸长率)随旋转速度增加而增加,随焊接速度减小而增加。焊接速度对热影响区显微硬度的影响比旋转速度更强。焊接速度和旋转速度对搅拌摩擦焊接接头的力学性能有重要影响,且其影响可用回归模型进行预测。 | C.SHARMA V.UPADHYAY D.K.DWIVEDI P.KUMAR | 2017 | Transactions of Nonferrous Metals Society of China2017，27，3： | 4 |
| 5 | Comparison of burn rate and thermal decomposition of AP as oxidizer and PVC and HTPB as fuel binder based composite solid propellants显示文摘In the present investigation an effort has been made to understand the thermal decomposition and burn rate characteristics of AP as oxidizer and PVC and HTPB as fuel binder in composite solid propellant. The burning rate study has been carried out at ambient and different pressures of 2.068 Mpa, 4.760 Mpa,6.895 Mpa. The mechanism of thermal decomposition of each composition have also been determined by NETZSCH simultaneous thermal analyser, comprising differential scanning calorimeter(DSC) and thermo-gravimetric analyser(TGA). An effort has been made to study the burn rate and decomposition of fuel binder and oxidizer in presence of Fe_2O_3 and also their overall impact on combustion of propellant. | A.Manash P.Kumar | 2019 | Defence Technology(防务技术)2019，15，2： | 4 |
| 6 | Regulation of Seed Germination:The Involvement of Multiple Forces Exerted via Gibberellic Acid Signaling显示文摘Seed germination is a key step in the life cycle of all seed plants, and it is of immense significance in agriculture.Germination is controlled by multiple environmental cues such as light and moisture,and endogenous factors,especially phytohormones.Gibberellic acid (GA)has long been identified as a critical hormone in the regulation of seed germination by countering the inhibition imposed by abscisic acid (ABA)(Holdsworth et al.,2008;Lee et al.,2010). | Pratibha Ravindran Prakash P.Kumar | 2019 | Molecular Plant2019，12，1： | 4 |
| 7 | Regulation of Seed Germination:The Involvement of Multiple Forces Exerted via Gibberellic Acid Signaling显示文摘(Molecular Plant 12,24–26;January 2019)In Figure 1,we highlight that the DELLA protein RGL2 interacts with DOF6,and this novel complex regulates GATA12 and other unidentified targets to inhibit dormancy release.However,we mistakenly used an arrowhead(suggesting positive regulation)towards dormancy release instead of the bar-ended line(suggesting negative regulation).The figure has thus been rectified with a bar-ended line.The authors apologize for this error. | Pratibha Ravindran Prakash P.Kumar | 2019 | Molecular Plant2019，12，10： | 3 |
| 8 | Group enclosing queries显示文摘 | F.Li B.Yao P.Kumar | | 0，，10： | 1 |
| 9 | Predicting uncertain behavior of industrial system using FM:a practical case显示文摘 | R.K.Sharma D.Kumar P.Kumar | | 0，，01： | 1 |
| 10 | Induction reheating of A356.2 aluminum alloy and thixocasting as automobile component显示文摘The development work for producing an automobile component by thixocasting using A356.2 alloy was introduced.As the first step,the alloy was electromagnetically stirred and solidified to produce a billet with non-dendritic microstructure.The microstructure depended on several process parameters such as stirring intensity,stirring frequency,cooling rate,and melt initial superheat.Through a series of computational studies and controlled experiments,a set of process parameters were identified to produce the best microstructures.Reheating of a billet with non-dendritic microstructure to a semisolid temperature was the next step for thixo-casting of the components.The reheating process was characterized for various reheating cycles using a vertical-type reheating machine.The induction heating cycle was optimized to obtain a near-uniform temperature distribution in radial as well as axial direction of the billet,and the heating was continued until the liquid fraction reached about 50%.These parameters were determined with the help of a computational fluid dynamics(CFD) model of die filling and solidification of the semisolid alloy.The heated billets were subsequently thixo-cast into automobile components using a real-time controlled die casting machine.The results show that the castings are near net shape,free from porosity,good surface finish and have superior mechanical properties compared to those produced by conventional die casting processes using the same alloy. | H.LAKSHMI M.C.VINAY KUMAR RAGHUNATH P.KUMAR V.RAMANARAYANAN K.S.S.MURTHY P.DUTTA | 2010 | 中国有色金属学会会刊:英文版2010，20，S3： | 1 |
| 11 | Numerical solution of generalized DPL model using wavelet method during thermal therapy applications显示文摘In this paper, generalized dual-phase-lag (DPL) model has been studied for the numerical analysis of spatial variation of temperature within living biological tissues during thermal therapy applications. A new hybrid numerical scheme based on finite difference scheme and Chebyshev wavelet Galerkin method are used to solve the generalized DPL model with constant heat flux boundary condition. Multi-resolution and multi-scale computational property of Chebyshev wavelet in the present case localizes small scale variations of solution and fast switching of functional bases. Our study demonstrates that due to presence of coupling factor (convection–perfusion), generalized DPL model predicts lower temperature than classical DPL and Pennes model at the tumor position. Higher values of phase lag times results in lower temperature at the tumor position. But, in case of variation of phase lag time due to temperature gradient, the nature of temperature profile also depends on the spatial coordinate. The effect of the blood temperature, porosity and interfacial convective heat transfer on temperature distribution has been investigated. It is found that larger values of porosity and interfacial convective heat transfer results in lower temperature at the tumor position. Also, both porosity and interfacial convective heat transfer are pronounced more at higher values. The whole analysis is presented in dimensionless form. | P.Kumar K.N.Rai | 2019 | International Journal of Biomathematics2019，12，3： | 1 |
| 12 | Simultaneous RP-HPLC estimation of nitazoxanide and ofloxacin in tablet dosage forms显示文摘 | R.Siva Kumar P.Kumar Nallasivan S.Saravanakumar | | 0，，： | 1 |
| 13 | 大叶相思木材的物理力学特性显示文摘前言大叶相思(Acacia auriculiformis)原产巴布亚新几内亚的萨温纳斯(托雷斯海峡诸岛)和澳大利亚北部。由于它能在极瘦瘠的土壤上生长,已为许多国家所引种,如印度尼西亚、马来西亚、坦桑尼亚和尼日利亚等。该树种生长旺盛,在原产地树高达30m、干径达60cm。它又是一种受人喜爱的观赏和遮荫树木,管理十分粗放。巴布亚新几内亚10年生大叶相思人工林的有关资料表明,其制浆产量高,力学性能好。 | P.Kumar 张富明 | 1990 | 广东林业科技1990，，4： | 1 |
| 14 | 'Managerial entrenchment and payout policr'显示文摘 | Hu A P.Kumar | | 0，，04： | 1 |
| 15 | Floral organ identity genes in the orchid Dendrobium crumenatum显示文摘 | YifengXu Lai LaiTeo JingZhou Prakash P.Kumar HaoYu | 2006 | The Plant Journal2006，，1： | 1 |
| 16 | RISC assembly and post-transcriptional gene regulation in Hepatocellular Carcinoma显示文摘RNA-induced silencing complex(RISC)is one of the basic eukaryotic cellular machinery which plays a pivotal role in post-transcriptional gene regulation.Discovery of miRNAs and their role in gene regulation have changed the course of modern biology.The method of gene silencing using small interfering RNAs and miRNAs has become major tool in molecular biology and genetic engineering.Hepatocellular Carcinoma(HCC)is a very common malignancy of liver in developing countries and due to various risk factors;the prevalence of this disease is rapidly increasing throughout the globe.There exists an imbalance in interplay between oncogenes and tumor suppressor genes and their regulation plays a major role in HCC growth,development and metastasis.The regulatory function of RISC and miRNAs make them a very important mediators of cancer signaling in HCC.Therefore,targeting the RISC complex for HCC therapy is the need of the time. | Prasanna K.Santhekadur Divya P.Kumar | 2020 | Genes & Diseases2020，7，2： | 1 |
| 17 | IMPEDANCE SPECTROSCOPY AND AC CONDUCTIVITY STUDIES OF FERROELECTRIC(K_(0.5)Na_(0.5))NbO_(3)CERAMICS显示文摘Lead free(K_(0.5)Na_(0.5))NbO_(3)(KNN)ceramics were prepared by conventional solid state reaction route.For single perovskite phase formation,calcination temperature was optimized at 850℃for 6h,whereas for dense morphology the sintering of the ceramic was carried out at 1120℃for 4h.X-ray diffraction XRD analysis confirmed the formation of single phase with orthorhombic structure at room temperature.Impedance analysis and AC conductivity studies of the KNN sample was carried out in the temperature range of 703-773 K.Impedance study showed the increase in conducting behavior at higher temperature.The temperature dependence of AC conductivity indicated that the conduction process is due to doubly ionized oxygen vacancies in the higher temperature region. | P.PALEI P.KUMAR | 2011 | Journal of Advanced Dielectrics2011，1，3： | 0 |
| 18 | DIRECT CORONAPY ANGIOPLASTY FOR ACUTE MYOCARDIAL INFARCTION:A SINGLE CENTRE EXPERIENCE显示文摘 | S.Kar E.Manolas P.Kumar R.Dick Y Lim M.Rowe | 1996 | 广东医学1996，17，S1： | 0 |
| 19 | 急性心肌梗塞的直接冠状动脉成形术:单中心经验显示文摘 | 张斌 S.Kar E.Manolas P.Kumar R.DIck 林廷龄 M.Rowe | 1996 | 广东医学1996，17，S1： | 0 |
| 20 | 氧化钙对锆石和硅线石海滩砂反应烧结制备莫来石-氧化锆复合材料热力性能的影响(英文)显示文摘采用印度沿海锆石粉与硅线石海滩砂反应烧结,制备含20%(质量分数)氧化锆的莫来石-氧化锆复合材料。添加4%~12%(摩尔分数)的氧化钙作为添加剂。研究了添加剂对压实性能、显微组织、力学性能和热力性能的影响。添加氧化钙可以使压实温度从1600°C降低至1550°C。氧化钙可以形成少量的液相(铝硅酸钙),有利于烧结进行。添加4%氧化钙可使复合材料的晶粒尺寸减小,当添加量大于4%时,材料的晶粒尺寸随氧化钙添加量的增加而增大。添加4%氧化钙样品的弯曲强度约为225MPa,断裂韧度约为6MPa·m^(1/2),且抗热冲击性能得到明显提高。氧化钙可以稳定四方氧化锆,从而提高材料的力学性能。 | P.KUMAR M.NATH A.GHOSH H.S.TRIPATHI | 2016 | Transactions of Nonferrous Metals Society of China2016，26，9： | 0 |
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