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	题名	作者	年代	出处	被引量
1	Usefulness of two independent hist classifications of tumor regression iUsefulness of two independent histopathological classifications of tumor regression in patients with rectal cancer submitted to hyperfractionated pre-operative radiotherapy显示文摘AIM: To assess the usefulness of two independent histopathological classifications of rectal cancer regression following neo-adjuvant therapy. METHODS: Forty patients at the initial stage cT3NxM0 submitted to preoperative radiotherapy (42 Gy during 18 d) and then to radical surgical treatment. The relationship between “T-downstaging” versus regressive changes expressed by tumor regression grade (TRG 1-5) and Nasierowska-Guttmejer classification (NG 1-3) was studied as well as the relationship between TRG and NG versus local tumor stage ypT and lymph nodes status, ypN. RESULTS: Complete regression (ypT0, TRG 1) was found in one patient. “T-downstaging” was observed in 11 (27.5%) patients. There was a weak statistical significance of the relationship between “T-downstaging” and TRG staging and NG stage. Patients with ypT1 were diagnosed as TRG 2-3 while those with ypT3 as TRG5. No lymph node metastases were found in patients with TRG 1-2. None of the patients without lymph node metastases were diagnosed as TRG 5. Patients in the ypT1 stage were NG 1-2. No lymph node metastases were found in NG 1. There was a significant correlation between TRG and NG. CONCLUSION: Histopathological classifications may be useful in the monitoring of the effects of hyperfractionated preoperative radiotherapy in patientswith rectal cancer at the stage of cT3NxM0. There is no unequivocal relationship between “T-downstaging” and TRG and NG. There is some concordance in the assessment of lymph node status with ypT, TRG and NG. TRG and NG are of limited value for the risk assessment of the lymph node involvement.	■ukasz Liszka Ewa Zielińska-Paj■k Jacek Paj■k Dariusz Goka Jacek Starzewski Zbigniew Lorenc	2007	World Journal of Gastroenterology2007，13，4：	2
2	INT0123 (Radiation Therapy Oneology Group 94-05) phase Ⅲ trial of combinedmodality therapy for esophageal eaneer: high-dose versus standard dose radiation therapy显示文摘	Minsky BD Paj ak TF Ginsberg R J	2002	J Clin Oncol2002，20，5：	1
3	Ca2+ and Na+ channels involved in neuronal cell death :proteetion by flunarizine显示文摘	Pauwels PJ Leysen JE Janssen PAJ	1991	Life Sei1991，48，：	1
4	Chronic pancreatitis显示文摘	Nair PaJ Lawler L Miller ME	2007	Am Fam Physician2007，76，11：	1
5	Health related quality of life in coronary patients and its association with their cardiovascular risk profile: Results from the EUROASPIRE III survey显示文摘	Delphine De Smedt Els Clays Lieven Annemans Frank Doyle Kornelia Kotseva Andrzej Paj?k Christof Prugger Catriona Jennings David Wood Dirk De Bacquer	2012	International Journal of Cardiology2012，，：	1
6	Computer Simulations of a Water/Oil Interface in the Presence of Micelles显示文摘	Smit B Hilbers PAJ Esselink K	1990	Nature1990，348，6302：	1
7	Training Affects the Collagen Framework of Subchondral Bone in Foals 显示文摘	PAJ Brama RA Bank	2001	The Veterinary Journal2001，162，：	1
8	Potent,New Analgesics,Tailor-made for different purpose显示文摘	Janssen PAJ	2001	Acta Anaesthesiol Scand2001，26，：	1
9	Hepatic glutaminase mRNA is confined to part of the urea cycle domain in the adult rodent liver lobule显示文摘	Moorman AFM de Boer PAJ Wafford M		0，，01：	1
10	Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter 显示文摘	van der Knaap MS Leegwater PAJ Konst AAM	2002	Ann Neurol2002，51，：	1
11	Variation in the short- term changes in bone cell activity in three regions of the distal fe- mur immediately following ovariectomy 显示文摘	Baldock PAJ Morris R J Need AG	2009	J Bone Miner Res2009，13，：	1
12	Development of an in vivo mouse model to study oral submucous fibrosis显示文摘	Sumeth Perera MW Gunasinghe D Perera PAJ	2007	Oral Pathol Med2007，36，27：	1
13	Inhibitor of ibbrinolyi are elevated in at heroclerotic plaque显示文摘	Robbbie LA Booth NA Brown PAJ	1996	Arteriocler Thromb Vac Biol1996，16，：	1
14	Application of cen- tral composite design to the optimisation of aqueous two-phase extraction of human antibodies显示文摘	Rosa PAJ Azevedo AM Aires-Barros MR	2007	J Chromatogr A2007，43，：	1
15	In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4- -2,6-dimethylphenyl]amino]- 2-pyrimidinyl]amino]benzonitrile (R278474, rilpivirine) 显示文摘	Janssen PAJ Lewi P J Arnold E	2005	J Med Chem2005，48，：	1
16	Yeast cell wall polysaccharides as antioxidants and antimutagens: can they fight cancer显示文摘	KOGAN G PAJ]TINKA M BABINCOVA M	2008	Neoolasma2008，55，5：	1
17	C-reactive protein and complement depositions in human infarcted myocardium are more extensive in patients with reinfarction or upon treatment with reperfusion显示文摘	Nijmeijer R Krijnen PAJ Assink J		0，，：	1
18	Myocardial Infarction and Coronary Deaths in the World Health Organization MONICA Project: Registration Procedures, Event Rates, and Case-Fatality Rates in 38 Populations From 21 Countries in Four Continents显示文摘	Hugh Tunstall-Pedoe Kari Kuulasmaa Philippe Amouyel Dominique Arveiler Anna-Maija Rajakangas Andrzej Paj&OV0539 k	1994	Circulation1994，，1：	1
19	Energy Metabolism显示文摘	Perera PAJ Marikar FMMT	2014	Bangladesh Journal of Medical Biochemistry2014，6，2：	1
20	Subunits of translation initiation factor eIF2B are mutant in leukoen cephalopathy with vanishing white matter 显示文摘	Leegwater PAJ Vermeuden G Konst AAM	2001	Nature Genet2001，29，4：	1

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