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| 1 | Diagnostic accuracy of endoscopic ultrasound in pancreatic neuroendocrine tumors: A systematic review and meta analysis显示文摘AIM: To detect pancreatic neuroendocrine tumors (PNETs) has been varied. This study is undertaken to evaluate the accuracy of endoscopic ultrasound (EUS) in detecting PNETs.METHODS: Only EUS studies confirmed by surgery or appropriate follow-up were selected. Articles were searched in Medline, Ovid journals, Medline nonindexed citations, and Cochrane Central Register of Controlled Trials and Database of Systematic Reviews. Pooling was conducted by both fixed and random effects model). RESULTS: Initial search identified 2610 reference articles, of these 140 relevant articles were selected and reviewed. Data was extracted from 13 studies (n = 456) which met the inclusion criteria. Pooled sensitivity of EUS in detecting a PNETs was 87.2% (95%CI: 82.2-91.2). EUS had a pooled specificity of 98.0% (95%CI: 94.3-99.6). The positive likelihood ratio of EUS was 11.1 (95%CI: 5.34-22.8) and negative likelihood ratio was 0.17 (95%CI: 0.13-0.24). The diagnostic odds ratio, the odds of having anatomic PNETs in positive as compared to negative EUS studies was 94.7 (95%CI: 37.9-236.1). Begg-Mazumdar bias indicator for publication bias gave a Kendall's tau value of 0.31 (P = 0.16), indication no publication bias. The P for χ2 heterogeneity for all the pooled accuracy estimates was > 0.10. CONCLUSION: EUS has excellent sensitivity and specificity to detect PNETs. EUS should be strongly considered for evaluation of PNETs. | Srinivas R Puli Nikhil Kalva Matthew L Bechtold Smitha R Pamulaparthy Micheal D Cashman Norman C Estes Richard H Pearl Fritz-Henry Volmar Sonu Dillon Michael F Shekleton David Forcione | 2013 | World Journal of Gastroenterology2013，19，23： | 14 |
| 2 | 显示文摘 | Pearl I A Beyer D L | 1950 | TAPPI1950，33，： | 1 |
| 3 | The baculovirus Autographa californica nuclear polyhedrosis virus genome includes apapain-like sequence显示文摘 | Rawlings N D Pearl L H Buttle D J | 1992 | Biol Chem Hoppe Seyler1992，373，： | 1 |
| 4 | Cerebral venous development in relation to developmental venous anomalies and Vein of Galen aneurysmal malformations显示文摘 | Pearl M Gregg L Gandhi D | | 0，，03： | 1 |
| 5 | Effects of meloxicam on milk production, behavior, and feed intake in dairy cows following assisted calving 显示文摘 | Newby N C Pearl D L Leblanc S J | 2013 | J Dairy Sci2013，96，6： | 1 |
| 6 | The anatomical distribution of skin cancers显示文摘 | PEARL D K SCOTT E L | 1986 | Int J Epidemiol1986，15，4： | 1 |
| 7 | Atmospheric deposition of nitrogen: implications for nutrient over- enrichment of coastal waters 显示文摘 | PEARL H W DENNIS R L WHITALL D R | 2002 | Estuaries and Coasts2002，25，4： | 1 |
| 8 | The Baeulovirus Autographa Californica Nuclear Polyhedrosis Virus Ge- nome Includes a Papain-like Sequence显示文摘 | RAWLINGS N D PEARL L H BUTTLE D J | 1992 | Biol Chem Hoppe Seyler1992，373，12： | 1 |
| 9 | The anatomical distribution of skin can cers显示文摘 | Pearl D K Scott E L | 1986 | Int J Epidemiol1986，15，4： | 1 |
| 10 | The use of outbreak information in the interpretation of clustering of reported cases of Escherichia coil O157 in space and time in Alberta, Canada, 2000-2002 显示文摘 | Pearl D L | 2006 | Journal of Epidemiological Infections2006，134，4： | 1 |
| 11 | Antimicrobial susceptibility of Escherichia coli F4,Pasteurella multocida,and Streptococcus suis isolates from a diagnostic veterinary laboratory and recommendations for a surveillance system显示文摘 | GLASS-KAASTRA S K PEARL D L REID-SMITH R J | 2014 | Can Vet J2014，55，4： | 1 |
| 12 | A prospec- tive study to examine the epidemiology of methicillin - resistant Staphylococcus anreus and Clostridium dlfiicile contamination in the general environment of three community hospitals in southern Ontario, Canada显示文摘 | FAIRES M C PEARL D L CICCOTELLI W A | 2012 | BMC infect diseases2012，8，12： | 1 |
| 13 | Four-year randomized prospective comparison of pere(ltaneous ePTFE/nitinol self-ex- panding stent graft versus prosthetic femoral-popliteal bypass in the treatment of superficial femoral artery occlusive disease 显示文摘 | McQuade K Gable D Pearl (L | 2010 | J Vasc Surg2010，52，3： | 1 |
| 14 | Combination of drugs and drugresistant reverse transcriptase results in a multiplicative in crease of human immuno deficiency virus type Ⅰ mutant frequencies显示文摘 | Mansky L M Pearl D K Gajary L C | 2002 | J Virol2002，76，： | 1 |
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