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| 1 | 未处理或上游法处理后精子的DNA碎片能否预测使用赠卵ICSI后的妊娠?显示文摘本研究比较了未处理的精子和上游法处理后精子中的DNA碎片值(SDF)预测使用赠卵ICSI后妊娠的可能性。总共81例不孕女性接受通过夫精和赠卵ICSI后的胚胎移植。这种方式排除了目前公认的影响精子DNA修复的女方因素。在ICSI受精时,同时使用DNA碎片率检测试剂盒(Halosperm)进行盲法检测未处理的和上游法处理后精液中的精子DNA碎片。经上游法处理后的精液样本中SDF值呈显著下降。有趣的是,未处理的或上游法处理后精液样本中的SDF值均能预测妊娠。通过ROC曲线和其衍生的约登指数计算得出未处理前和上游法处理后精子sDF的临界值分别是24.8%和17.5%。未处理精子SDF预测妊娠的敏感性和特异性分别为75%和69%,而上游法处理后的精子SDF预测妊娠的敏感性和特异性分别是78%和73%。虽然SDF值增高与生育呈负相关,但我们发现在精子筛选降低sDF值后再与赠卵进行ICSI并不能保证获得妊娠。这表明目前的技术手段对于一些DNA损伤仍无法探及,从而相对影响辅助生殖成功的机率。因此,我们认为对目前的“冰山模式”作一些修饰后可以用来解释SDF在生育中的作用。 | Jaime Gosálvez Pedro Caballero Carmen López-Fernández Leonor Ortega José Andrés Guijarro José Luís FernAndez Stephen D Johnston Rocio Nufiez-Calonge | 2013 | Asian Journal of Andrology2013，15，6： | 3 |
| 2 | Effects of feeding yeast(Saccharomyces cerevisiae), organic selenium and chromium mixed on growth performance and carcass traits of hair lambs显示文摘Yeasts and organic minerals are used in diets to improve health, productive performance and some carcass characteristics of ruminants and non-ruminants. Thirty-two lambs(Pelibuey×Katahdin; BW=(30.55±1.67) kg; n=8) were used in a 56-d feeding experiment to study the effects of different levels of live yeast(Saccharomyces cerevisiae; yeast), selenium(Se) and chromium(Cr) mixed(Se-Cr), and a mixture of yeast-Se-Cr on growth performance and carcass traits. Animals were stratified by body weight(BW) and randomly assigned to one of four treatments: 1) control group(0.0 g kg–1 yeast); 2) yeast(1.50 g kg–1 dry matter intake(DMI) d–1); 3) Se-Cr premix(1.5 mg kg–1 DMI d–1 for each mineral); and 4) yeast-Se-Cr mixture. There were no treatment effects on final BW; whereas lambs fed Se-Cr or yeast-Se-Cr had higher(P<0.05) DMI than animals supplemented with only yeast. Average daily gain(ADG), gain:feed ratio, chop area, dorsal fat and carcass yield were similar(P>0.05) among treatment groups. In conclusion, supplementation with yeast, Se-Cr mixed or yeast-Se-Cr did not improve ADG, final BW, back fat content and carcass yield of growing of Pelibuey×Katahdin lambs. Supplementation with Se-Cr and yeast-Se-Cr increased DMI, and approximately 250 g ADG animal–1 d–1 was produced with no negative effects on growth and health of the animals. | Pedro A Hernández-García Alejandro Lara-Bueno Germán D Mendoza-Martínez José R Bárcena-Gama Fernando X Plata-Pérez Rufino López-Ordaz José A Martínez-García | 2015 | Journal of Integrative Agriculture2015，14，3： | 2 |
| 3 | Effect of human chorionic gonadctrophin supplementation during different culture periods on in viro maturation of canine oocytes显示文摘 | Monica D R Johanna D L Pedro M | 2005 | Theriogenology2005，64，： | 1 |
| 4 | Adaptive control for a radio-controlled helicopter in a vertical flying stand 显示文摘 | Alejandro D Rogelio L Pedro C | 2004 | International Journal of Adaptive Control and Signal Processing2004，18，5： | 1 |
| 5 | Climate change and recent waler level variability in Patagonian proglacial lakes, Argentina 显示文摘 | Andrea I P Karina L L Pedro J D | 2008 | Global and Planetary Change2008，63，4： | 1 |
| 6 | Stability of polytopes of matrices via affine parameter dependent Lyapunov functions: asymptotically exact LMI conditions 显示文摘 | Ricardo C L Pedro L D | 2005 | Linear Algebra and Its Applications2005，405，： | 1 |
| 7 | Parameter dependent LMI in robust analysis: characterization of homogeneous polynomially parameter dependent solutions via LMI relaxations 显示文摘 | Ricardo C L Pedro L D | 2007 | IEEE Transactions on Automatic Control2007，52，7： | 1 |
| 8 | Growth and proteolytic activity of hairy roots from Centaurea calcitrapa: effect of nitrogen and sucrose 显示文摘 | Pedro M L L Susana D C Tiago M M | 2002 | Enzyme Microb Technol2002，31，： | 1 |
| 9 | Fatty acid esters of triterpenes from Erythroxylum passerinum显示文摘 | MARIZETH L B JORGE M D PEDRO A P P | 2002 | J Braz Chem Soc2002，13，5： | 1 |
| 10 | Chemical composition of flavonoids and styrylpyrones and the genetic variability of isozymes in natural populations of Cryptocarya mandioccana Meisner (Lauraceae)显示文摘 | PEDRO L R D CLAUDIA J N MERCELO C A | 2007 | Biochem Syst Ecol2007，35，4： | 1 |
| 11 | Exploring dimensionality reduction of EEG features in motor imagery task classification 显示文摘 | PEDRO J G L GERMAN R B JOAQUIN R D | 2014 | Expert Systems with Applications2014，41，11： | 1 |
| 12 | A LMI condition for the robust stability of uncertain continuous-time linear systems显示文摘 | DOMINGOS C W RAMOS PEDRO L D | 2002 | IEEE Trans on Automatic Control2002，47，4： | 1 |
| 13 | REE distribution pattern in river sediments: Partitioning into residual and labile fractions 显示文摘 | Lydia L Jean-Luc P Pedro D | 1999 | Earth and Planetary Sciences Letters1999，329，： | 1 |
| 14 | Convergent LMIrelaxations for robust analysis of uncertain linear systems usinglifted polynomial parameter-dependent lyapunov functions 显示文摘 | Ricardo C L Mauricio C 0 Pedro L D | 2008 | Systems & Control Letters2008，57，8： | 1 |
| 15 | Perform- ance of textile and building materials for a particular evapora- tive cooling purpose 显示文摘 | PIRES L SILVA Pedro D CASTRO Gomes J P | 2011 | Experimental Thermal and Fluid Sci- ence2011，35，： | 1 |
| 16 | Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol显示文摘 | Pedro Ayala José Montenegro Raúl Vivar Alan Letelier Pablo Aránguiz Urroz Miguel Copaja Deisy Pivet Claudio Humeres Rodrigo Troncoso José Miguel Vicencio Sergio Lavandero Guillermo Díaz-Araya | 2011 | Experimental and Molecular Pathology2011，，1： | 1 |
| 17 | The linear interpo- lation method: a sampling theorem approach 显示文摘 | Peres Pedro L D Bonatti Ivanil S Borelli Walter C | 2003 | Controle y Au- tomacao2003，14，4： | 1 |
| 18 | Quantification of cardiac ventricular repolarization and its spatial dispersion through the surface electrocardiogram 显示文摘 | Pedro D Eric L | 2009 | Rev Argent Cardiol2009，77，： | 1 |
| 19 | Lipoprotein(a) levels in Familial Hipercholesterolaemia: an important predictor for cardiovascular disease independent of the type of LDL-receptor mutation显示文摘 | Rodrigo Alonso Eduardo Andres Nelva Mata Francisco Fuentes-Jiménez Lina Badimón José López-Miranda Teresa Padró Ovidio Mu?iz Jose Luis Díaz-Díaz Marta Mauri Jose María Ordovás Pedro Mata Rocío Aguado | 2014 | Journal of the American College of Cardiology2014，，： | 1 |
| 20 | Entropic approach to edge detection for SST images显示文摘 | Vázquez D P Chakir Atae-Allah Pedro L L | | 0，，： | 1 |
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