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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | 中阿40m射电望远镜选址与电磁环境监测显示文摘优良站址的选择是射电望远镜完成既定科学目标并实现高效运行的重要保障。影响射电望远镜选址的主要因素包括电磁环境、水文、气象、地质条件、隔离性与可及性等。对于射电天文观测而言,来自宇宙天体的射电信号往往极其微弱,对望远镜系统及设备的灵敏度要求极高。然而,随着人类活动的不断加强,人们日常工作和生活中使用的电子通讯设备越来越多,无线电干扰源呈爆炸式涌现。在射电望远镜选址工作中,进行电磁环境监测,选择一个电磁环境良好的站址,对于射电望远镜实现常规观测运行、获取有效数据资料至关重要。同时,电磁环境监测结果也是射电望远镜接收机系统研制、站址电磁环境及无线电宁静区立法保护的重要依据。中阿天文学者和技术人员历时1年半完成了16个候选站址的初步勘察,并对优选出的3个主要候选站址进行了深入细致的电磁环境监测工作,获得了大量可靠数据。中阿双方依据电磁环境监测结果并结合各主要候选站址的水文、气象、地质及道路等条件,最终将位于Talacasto戈壁的3号候选站址确定为中阿CART射电望远镜的建设站点。 | 赵卫普 李建斌 李金增 孙建民 齐力 罗滔 马晓耘 莫铠玮 李鹏程 夏跃兵 MALLAMACI C C PODESTA R C PACHECO A M ACTIS E CASTRO J I ALVIS R H LOPEZ C E FRANCILE C PODESTA F PEREZ J | 2014 | 天文学进展2014，32，3： | 4 |
| 3 | Optimization of the production of a honeybee odorant-binding protein by Pichia pastoris 显示文摘 | Briand L Perez V Huet J C | 1999 | Protein Expression Purification1999，15，： | 2 |
| 4 | Influence of complexing carboxymethylcellulose on the thermostability and gelation of α-lactalbumin and β-lactoglobulin显示文摘 | CAPITANI C PEREZ O E PACHECO B | 2007 | Food Hydrocolloids2007，21，： | 1 |
| 5 | Sharp weighted estimates for multilinear commutators显示文摘 | PEREZ C TRUJILLO G R | 2002 | J London Math Soe2002，65，2： | 1 |
| 6 | Technological revolutions and techno - economic paradigms 显示文摘 | Perez C | 2010 | Cambridge Journal of Economics2010，34，1： | 1 |
| 7 | Stereotactic biopsy for brainstem tumors in pediatric patients 显示文摘 | PEREZ GOMEZ J L RODRIGUEZ ALVAREZ C A MARHX BRACHO A | 2010 | Childs Nerv Syst2010，26，1： | 1 |
| 8 | Non-toxic alternative compounds for marine antifouling paints显示文摘 | Stupak M E Garcia M T Perez M C | 2003 | International Biodeterioration & Biodegradation2003，52，1： | 1 |
| 9 | Radiation therapy morbidity in carcinoma of the uterine cervix: Dosimetric and clinical correlation显示文摘 | PEREZ C A GRIGSBY P W LOCKETr M A | 1999 | Int J Radiat Oncol Biol Phys1999，44，4： | 1 |
| 10 | Inheritance of tomato yellow leaf curl virus resistance derived from Solanum pimpinellifolium UPV16991显示文摘 | Perez de C A Dlez M J Nuez F | 2007 | Plant Dis2007，91，7： | 1 |
| 11 | Solubility and toxic effect of the cuprous thiocyanate antifouling pigment on barnacle larvae 显示文摘 | Vetere V F Perez M C | 1997 | Journal of Coatings Technology1997，69，866： | 1 |
| 12 | Hilbert-Huang adysis of BWR neutron detector signals: Application to DR calculation and to corrupted signal analysis显示文摘 | Montesinos M E Munoz - Cobo L Perez C | 2003 | Annals of Nuclear Energy2003，30，： | 1 |
| 13 | Stability of the secondary antioxidant bis (2,4 - di - tert - butylphenyl) pentaerythritol diphosphite in food simulants 显示文摘 | Perez L C Rijk R Simal G J | 1998 | Journal of Agricultural and Food Chemistry1998，46，2： | 1 |
| 14 | Breeding cycle of the northern scallop, Argopecten purpuratus (Lamarck, 1819) in southern Chile 显示文摘 | Gonzalez M L Perez M C Lopez D A | 2002 | Aquaculture Research2002，33，11： | 1 |
| 15 | Swelling- solubility characteristics, granule size distribution and rheological behavior of banana ( Musa paradisiaca ) starch 显示文摘 | Nunez- Santiago M C Bello- Perez L A Tecante A | 2004 | Carbohydrate Polymers2004，56，1： | 1 |
| 16 | Callus induction and a preliminary attempt to obtain cell suspensions from embryos and levels of Juglans regia L 显示文摘 | Rodriguez R Revilla M A Perez C | 1987 | Acta Hort (ISHS)1987，12，： | 1 |
| 17 | Abandoned mine sites as a source of contamination by heavy metals:A case study in a semi-arid zone显示文摘 | Navarro M C Perez S C Martinez S M J | 2008 | Journal of Geochemical Exploration2008，96，23： | 1 |
| 18 | Biosynthesis of strawberry aroma compounds through amino acid metabolism显示文摘 | Perez A G Olias R Luaces P Sanz C | 2002 | Journal of Agricultural and Food Chemistry2002，50，14： | 1 |
| 19 | Anti - MDR1 siRNA re- stores chemosensitivity in chemoresistant breast carcinoma and os- teosarcoma cell lines显示文摘 | PEREZ J BARDIN C RIGAL C | 2011 | Anticancer Res2011，31，9： | 1 |
| 20 | Pulmonary embolism in patients with unexplained exacerbation of chronic obstructive pulmonary disease: Prevalence and risk factors显示文摘 | Tillie-Leblond I Marquette C H Perez T | 2006 | Ann Intern Med2006，144，： | 1 |
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