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| 1 | Predictors of suboptimal bowel preparation in asymptomatic patients undergoing average-risk screening colonoscopy显示文摘AIM To identify risk factors for a suboptimal preparation among a population undergoing screening or surveillance colonoscopy.METHODS Retrospective review of the University of Michigan and Veteran's Administration(VA) Hospital records from 2009 to identify patients age 50 and older who underwent screening or surveillance procedure and had resection of polyps less than 1 cm in size and no more than 2 polyps. Patients with inflammatory bowel disease or a family history of colorectal cancer were excluded. Suboptimal procedures were defined as procedure preparations categorized as fair, poor or inadequate by the endoscopist. Multivariable logistic regression was used to identify predictors of suboptimal preparation.RESULTS Of 4427 colonoscopies reviewed, 2401 met our inclusion criteria and were analyzed. Of our population, 16% had a suboptimal preparation. African Americans were 70% more likely to have a suboptimal preparation(95%CI: 1.2-2.4). Univariable analysis revealed that narcotic and tricyclic antidepressants(TCA) use, diabetes, prep type, site(VA vs non-VA), and presence of a gastroenterology(GI) fellow were associated with suboptimal prep quality. In a multivariable model controlling for gender, age, ethnicity, procedure site and presence of a GI fellow, diabetes [odds ratio(OR) = 2.3; 95%CI: 1.6-3.2], TCA use(OR = 2.5; 95%CI: 1.3-4.9), narcotic use(OR = 1.7; 95%CI: 1.2-2.5) and Miralax-Gatorade prep vs 4L polyethylene glycol 3350(OR = 0.6; 95%CI: 0.4-0.9) were associated with a suboptimal prep quality. CONCLUSION Diabetes, narcotics use and TCA use were identified as predictors of poor preparation in screening colonoscopies while Miralax-Gatorade preps were associated with better bowel preparation. | Shail M Govani Eric E Elliott Stacy B Menees Stephanie L Judd Sameer D Saini Constantinos P Anastassiades Annette L Urganus Suzanna J Boyce Philip S Schoenfeld | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，17： | 7 |
| 2 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 3 | Intrinsic viscosity of dendrimers via equi- librium molecular dynamics 显示文摘 | Philip M D David B A | 2005 | Soft Matter2005，1，2： | 1 |
| 4 | Voriconazole - Associated Phototoxicity 显示文摘 | Ryan R Riahi B S Philip R Cohen M D | 2011 | Dermatology Online Journal2011，17，2： | 1 |
| 5 | The analytical investigation of synthetic street drugs containing cathinone analogs显示文摘 | Amanda M L Philip B S Adriana D A | 2014 | Forensic Sci Int2014，234，： | 1 |
| 6 | Effects of Loading Frequency and Stress Reversal on Fatigue Life of Plain Concrete显示文摘 | Zhang B Philips D V Wu K | 1996 | Magazine of Concrete Research1996，48，177： | 1 |
| 7 | Proapoptotic effects of AngⅡ in human coronary artery endothelial cells:Role of AT1 receptor ansd PKC activation显示文摘 | Li D Yang B Philips MI | 1999 | Am J Physiol1999，276，： | 1 |
| 8 | A preliminary assessment of consumer's exposure to organochlorine pesticides in fruits and vegetables and the potential health risk in Acera Metropolis,Ghana显示文摘 | CRENTSIL K B AUGUSTINE D PHILIP O Y | 2011 | Food Chemistry2011，128，4： | 1 |
| 9 | The future of electrical and computer engineering education显示文摘 | Frederick C B Philip S D Susan L S | 2003 | IEEE Transactions on Education2003，46，4： | 1 |
| 10 | Detection of adulteration of California orange juice concentrates with externally added carotenoids by liquid chromatography显示文摘 | PHILIP T CHEN T S & NELSON D B | 1989 | J Agric Food Chem1989，37，1： | 1 |
| 11 | The accumulation of cosmogenic chlorine-36 in rocks: A method for surface exposure dating 显示文摘 | Philips F M Leavy B D Jannik N O | 1986 | Science1986，231，： | 1 |
| 12 | Synthesis of insecticidal fluorinated anthranilic diamides显示文摘 | Clark D A Philip L G Smith B K | 2008 | Bioorganic&Medicinal Chemistry Letters2008，16，6： | 1 |
| 13 | Formulation of colored fiber blends from friele' s theoretical model 显示文摘 | Philips Invemizzi B Dupont D Caze C | 2002 | Color Research and Application2002，27，3： | 1 |
| 14 | Corona onset as a design optimization criterion for high voltage hardware 显示文摘 | Philips D B Olsen R G Pedrow P D | 2000 | IEEE Transactions on Dielectric and Electrical Insulation2000，7，6： | 1 |
| 15 | Color formulation by fiber blending using the Stearns-Noechel model 显示文摘 | Philips Invemizzi B Dupont D Jolly A | 2002 | Color Research and Application2002，27，2： | 1 |
| 16 | Color formulation by fiber blending using the Stearns-Noechel model显示文摘 | Philips B Dupont D Jolly A | 2002 | Color Research and Application2002，27，2： | 1 |
| 17 | An Empirical Examination Of VolatiliW Spillover Between the Indian and Us Swap Markets显示文摘 | Vivek B Malhotra D K Philip R Rahul S | 2012 | Intemational Journal of Emerging Markets2012，7，3： | 1 |
| 18 | Prevention of aflatoxieosis by addition of hydrated sodium calcium aluminositicate to the diets of growing barrows显示文摘 | Harvey R B Kubena L F Philips T D Huff W E Corrier D E | 1989 | Am J Vet Res1989，50，： | 1 |
| 19 | Recommendations for noncardisc surgery in aortic stenosis显示文摘 | Messika-Zeitoun D Iung B Philip I | 2005 | Ann Cardiol Angeiol2005，54，3： | 1 |
| 20 | Controlled tamponade of severe presaeral venous hemorrhage use of a breast implant sizer 显示文摘 | Sott C Braley B Philip D | 2006 | Dis Colon Rectum2006，45，2： | 1 |
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