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| 1 | Capsule endoscopy of the future: What's on the horizon?显示文摘Capsule endoscopes have evolved from passively moving diagnostic devices to actively moving systems with potential therapeutic capability. In this review,we will discuss the state of the art, define the current shortcomings of capsule endoscopy, and address research areas that aim to overcome said shortcomings.Developments in capsule mobility schemes are emphasized in this text, with magnetic actuation being the most promising endeavor. Research groups are working to integrate sensor data and fuse it with robotic control to outperform today's standard invasive procedures, but in a less intrusive manner. With recent advances in areas such as mobility, drug delivery, and therapeutics, we foresee a translation of interventional capsule technology from the bench-top to the clinical setting within the next 10 years. | Piotr R Slawinski Keith L Obstein Pietro Valdastri | 2015 | World Journal of Gastroenterology2015，21，37： | 8 |
| 2 | Advanced endoscopic technologies for colorectal cancer screening显示文摘Colorectal cancer is the third most common cancer in men and the second most common cancer in women worldwide. Diagnosing colorectal has been increasingly successful due to advances in technology. Flexible endoscopy is considered to be an effective method for early diagnosis and treatment of gastrointestinal cancer, making it a popular choice for screening programs. However, millions of people who may benefit from endoscopic colorectal cancer screening fail to have the procedure performed. Main reasons include psychological barriers due to the indignity of the procedure, fear of procedure related pain, bowel preparation discomfort, and potential need for sedation. Therefore, an urgent need for new technologies addressing these issues clearly exists. In this review, we discuss a set of advanced endoscopic technologies for colorectal cancer screening that are either already available or close to clinical trial. In particular, we focus on visual-inspectiononly advanced flexible colonoscopes, interventional colonoscopes with alternative propulsion mechanisms, wireless capsule colonoscopy, and technologies for intraprocedural bowel cleansing. Many of these devices have the potential to reduce exam related patient discomfort, obviate the need for sedation, increase diagnostic yield, reduce learning curves, improve access to screening, and possibly avert the need for a bowel preparation. | Keith L Obstein Pietro Valdastri | 2013 | World Journal of Gastroenterology2013，19，4： | 4 |
| 3 | Uncertainty about Government Policy and Stock Prices显示文摘 | L?UBOS? PáSTOR PIETRO VERONESI | 2012 | The Journal of Finance2012，，4： | 3 |
| 4 | Comprehensive review of autoantibodies in patients with hyper-IgM syndrome显示文摘Hyper-immunoglobulin M syndrome is an X-linked primary immunodeficiency disease caused by mutations in the CD40 ligand gene.The CD40 ligand has been recently highlighted as playing a key role in the pathogenesis of primary biliary cholangitis.In the present study,we assessed an extensive set of serum autoantibodies in a series of well-defined patients with hyper-immunoglobulin M syndrome.Serum,liver-related and liver-not-related autoantibodies IgG,IgM and IgA were tested by ELISA and standard indirect immunofluorescence in HEp-2 cells in 13 Tunisian patients(8 males and 5 females,aged 1–12 years)with hyper-immunoglobulin M syndrome during 1995–2012 and,as controls,21 age-and gender-matched blood donors.The level of IgM antibody against MIT3 was significantly higher in patients than in controls(35.8 vs 10.7,P=0.002).Half of the hyperimmunoglobulin M syndrome patients were found to be anti-MIT3 IgM positive vs none of the controls(Po0.0001).Twenty-three percent of patients were found to be anti-sp100 antibody positive vs only 0.05%of controls.By immunofluorescence,92.3%of patients were MIT3 IgM positive vs none of the controls.In conclusion,the IgM class of anti-MIT3 antibodies was shown to be present by both ELISA and immunofluorescence in most of the patients with hyper-immunoglobulin M syndrome.The presence of the hallmark of primary biliary cholangitis,a disease where the CD40 ligand is a key player,in an immunodeficiency disease caused by mutations in the CD40 ligand gene is very intriguing and opens new scenarios in understanding the immune pathogenesis of primary biliary cholangitis. | Mohamed-Ridha Barbouche Qubo Chen Marco Carbone Imen Ben-Mustapha Zakera Shums Mehdi Trifa Federica Malinverno Francesca Bernuzzi Haiyan Zhang Nourhen Agrebi Gary L Norman Christopher Chang M Eric Gershwin Pietro Invernizzi | 2018 | Cellular & Molecular Immunology2018，15，6： | 2 |
| 5 | Resection of Nonresectable Liver Metastases from Colorectal Cancer After Neoadjuvant Chemotherapy显示文摘 | Henry Bismuth René Adam Fran?is Lévi Christian Farabos Fabio Waechter Denis Castaing Pietro Majno Luc Engerran | 1996 | Annals of Surgery1996，，4： | 2 |
| 6 | Effect of aging on circadian rhythm of atrial natriuretic Peptide, plasma rennin activity and plasma aldosterone显示文摘 | Pietro C Piernatale L Loredana DP | 1992 | J Gerontology1992，47，： | 2 |
| 7 | No evidence of involvement of Chlamydia pneumoniae in lung cancer by means of quantitative real-time polyrnerase chain reaction 显示文摘 | Sessa R Santino l Di Pietro M | 2008 | Int J Dnmunopathol Pharmacol2008，21，2： | 1 |
| 8 | Model Checking Semantical- ly Annotated Services 显示文摘 | Pietro I D Pagliarecci F Spalazzl L | 2012 | IEEE Transactions on Software En- gineering(TSE)2012，38，3： | 1 |
| 9 | Lung Recruitment in patients with the acute respiratory distress syndrome显示文摘 | Luciano L Pietro C Massimo C | 2006 | N Engl J Med2006，354，17： | 1 |
| 10 | Neurospheres enriched in cancer stem like cells are highly effective in eliciting a den- dritic cell mediated immune response against malignant gliomas 显示文摘 | Serena P Pietro L P Daniela C | 2006 | Cancer Res2006，66，10： | 1 |
| 11 | Effect of curing temperature and type of cement on early-age shrinkage of high-performance concrete显示文摘 | Pietro L Klaas van B Ippei M | 2001 | Cement and Concrete Research2001，31，12： | 1 |
| 12 | Corro-sion Behaviour of Steel in Concrete in the Presence ofStray Current显示文摘 | BERTOLINI L MADDALENA C PIETRO P | 2007 | Corrosion Science2007，49，8： | 1 |
| 13 | Closing capacity and gas exchange in chronic heart failure显示文摘 | ROBERTO T CARLO G PIETRO G L | 2006 | Chest2006，129，： | 1 |
| 14 | A New Technique of Laparoscopic Intracorporeal Anastomosis for Transrectal Bowel Resection With Transvaginal Specimen Extraction显示文摘 | Emilie Faller Jaime Albornoz Pietro Messori Jo?l Leroy Arnaud Wattiez | 2013 | The Journal of Minimally Invasive Gynecology2013，，3： | 1 |
| 15 | Environmental Contaminants in Hospital Settings and Progress in Disinfecting Techniques显示文摘 | Gabriele Messina Emma Ceriale Daniele Lenzi Sandra Burgassi Elena Azzolini Pietro Manzi Marc Léone | 2013 | BioMed Research International2013，，： | 1 |
| 16 | Estimating preferential water flow parameters using a binary genetic algorithm inverse method显示文摘 | MAJDALANI S ANGULO-JARAMILLO R Di PIETRO L | 2008 | Environmental Modelling & Software2008，23，7： | 1 |
| 17 | Surgical treatment of giant pituitary adenomas:strategies and results in a series of 95 consecutive patients显示文摘 | Pietro M Raffaella B Marco L | 2007 | Neurosurgery2007，60，： | 1 |
| 18 | Derivatives of erythropoietin that are tissue protective but not erythropoietic显示文摘 | Marcel L Pietro G Giovanni G | 2004 | Science2004，305，5681： | 1 |
| 19 | Gastroprotective effect of the ethanolic extract and fractions obtained from Syngonanthus bisulcatus Rul显示文摘 | Batista LM de Almeida ABA de Morais Lima R de Sousa Falc(a)o H Ferreira AL de Pietro Magri L Coelho RG Calvo TR Vilegas W Monteiro Souza Brito AR | | 0，，1： | 1 |
| 20 | Scales and dimensions of momentum dissipation during preferential flow in soils显示文摘 | Germann P F Pietro L D | 1999 | Water Resources Reserches1999，35，5： | 1 |
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