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| 1 | Food groups, diet quality and colorectal cancer risk in the Basque Country显示文摘BACKGROUND The results obtained to date concerning food groups,diet quality and colorectal cancer(CRC)risk vary according to criteria used and the study populations.AIM To study the relationships between food groups,diet quality and CRC risk,in an adult population of the Basque Country(North of Spain).METHODS This observational study included 308 patients diagnosed with CRC and 308 ageand sex-matched subjects as controls.During recruitment,dietary,anthropometric,lifestyle,socioeconomic,demographic and health status information was collected.Adherence to the dietary recommendations was evaluated utilizing the Healthy Eating Index for the Spanish Diet and the MedDietScore.Conditional logistic regressions were used to evaluate the associations of food group intakes,diet quality scores,categorized in tertiles,with CRC risk.RESULTS The adjusted models for potential confounding factors showed a direct association between milk and dairy products consumption,in particular high-fat cheeses[odds ratio(OR)third tertile vs first tertile=1.87,95%confidence intervals(CI):1.11-3.16],and CRC risk.While the consumption of fiber-containing foods,especially whole grains(OR third tertile vs first tertile=0.62,95%CI:0.39-0.98),and fatty fish(OR third tertile vs first tertile=0.53,95%CI:0.27-0.99)was associated with a lower risk for CRC.Moreover,higher MD adherence was associated with a reduced CRC risk in adjusted models(OR third tertile vs first tertile=0.40,95%CI:0.20-0.80).CONCLUSION Direct associations were found for high-fat cheese,whereas an inverse relation was reported for fiber-containing foods and fatty fish,as well as adherence to a Mediterranean dietary pattern. | Iker Alegria-Lertxundi Carmelo Aguirre Luis Bujanda Francisco J Fernandez Francisco Polo JoseMªOrdovas MªCarmen Etxezarraga Inaki Zabalza Mikel Larzabal Isabel Portillo Marian M de Pancorbo Koldo Garcia-Etxebarria Ana MªRocandio Marta Arroyo-Izaga | 2020 | World Journal of Gastroenterology2020，26，28： | 3 |
| 2 | Bovine immunoglobulin protein isolates for the nutritional management of enteropathy显示文摘The gastrointestinal tract is responsible for a multitude of digestive and immune functions which depend upon the balanced interaction of the intestinal microbiota, diet, gut barrier function, and mucosal immune response. Disruptions in one or more of these factors can lead to intestinal disorders or enteropathies which are characterized by intestinal inflammation, increased gut permeability, and reduced capacity to absorb nutrients. Enteropathy is frequently associated with human immunodeficiency virus(HIV) infection, inflammatory bowel disease, autoimmune enteropathy, radiation enteritis, and irritable bowel syndrome(IBS), where pathologic changes in the intestinal tract lead to abdominal discomfort, bloating, abnormal bowel function(e.g., diarrhea, urgency, constipation and malabsorption). Unfortunately, effective therapies for the management ofenteropathy and restoring intestinal health are still not available. An accumulating body of preclinical studies has demonstrated that oral administration of plasmaor serum-derived protein concentrates containing high levels of immunoglobulins can improve weight, normalize gut barrier function, and reduce the severity of enteropathy in animal models. Recent studies in humans, using serum-derived bovine immunoglobulin/protein isolate, demonstrate that such protein preparations are safe and improve symptoms, nutritional status, and various biomarkers associated with enteropathy. Benefits have been shown in patients with HIV infection or diarrhea-predominant IBS. This review summarizes preclinical and clinical studies with plasma/serum protein concentrates and describes the effects on host nutrition, intestinal function, and markers of intestinal inflammation. It supports the concept that immunoglobulin-containing protein preparations may offer a new strategy for restoring functional homeostasis in the intestinal tract of patients with enteropathy. | Bryon W Petschow Anthony T Blikslager Eric M Weaver Joy M Campbell Javier Polo Audrey L Shaw Bruce P Burnett Gerald L Klein J Marc Rhoads | 2014 | World Journal of Gastroenterology2014，20，33： | 2 |
| 3 | Adsorption of benzotriazole on copper electrode surfaces in citric acid media 显示文摘 | Bastidas J M Pinilla P Polo J L | 2002 | Corrosion2002，58，11： | 1 |
| 4 | Learning in chemistry with virtual laboratories显示文摘 | Jimenez P M Pedrajas A P Polo J | 2003 | Journal of Chemieal Edueation2003，80，3： | 1 |
| 5 | Pulsed laser deposition of diamond from graphite targets显示文摘 | Cifre J Sanchez G | 1995 | Applied Physics Letters1995，67，4： | 1 |
| 6 | 显示文摘 | Polo M C Martinez E Esteve J | 1999 | Diamond Rel Mater1999，8，： | 1 |
| 7 | 显示文摘 | SANCHEZ - POLO M RIVERA - UTRILLA J ZAROR C A | 2002 | J Chem Technol Biotechnol2002，77，： | 1 |
| 8 | When fibroblasts MET iPSCs显示文摘 | Polo J M Hochedlinger K | 2010 | Cell Stem Cell2010，7，1： | 1 |
| 9 | Virus-based vectors for human vaccine applications显示文摘 | Polo J M Dubensky T W | 2002 | Drug Discov Today2002，7，： | 1 |
| 10 | Removal of pharmaceutical compounds,nitroimidazoles,from waters by using the ozone/carbon system显示文摘 | Sánchez Polo M Rivera Utrilla J Prados Joya G | 2008 | Water Res2008，42，15： | 1 |
| 11 | Adsorption of benzotriazole on copper electrode surface in citric acide midia 显示文摘 | Bastidas J M Pinilla P Polo J L | 2002 | Corrosion2002，58，11： | 1 |
| 12 | Effect of TGF-beta2 on proliferative scar fibroblast cell kinetics 显示文摘 | Polo M Smith P D Kim Y J | 1999 | Ann Plast Surg1999，43，2： | 1 |
| 13 | Layered amplification of gene expression with a DNA gene delivery system显示文摘 | Latham E M Polo J M | 1995 | Ann N Y Acad Sci1995，27，772： | 1 |
| 14 | Copper and zinc adsorption by sewage sludge-treated soil in southern Spain显示文摘 | Polo M J Ordonez R Giráldez J V | 1999 | Commun Soil Sci Plant Anal1999，30，： | 1 |
| 15 | Formation of biogenic amines throughout the in- dustrial manufacture of red wine 显示文摘 | MARCOBAL A MARTIN-ALVAREZ P J POLO M C | 2006 | Journal of Food Protection2006，69，2： | 1 |
| 16 | Efficiency of activated carbon to transform ozone into OH radi-cals:influence of operational parameters显示文摘 | SNCHEZ POLO M GUNTEN U V RIVERA UTRILLA J | 2005 | Water Research2005，39，14： | 1 |
| 17 | Generating Three-tier Applications from Relational Databases显示文摘 | Polo M Gomez J A Piattini M | 2002 | A Formal and Practical Approach Information and Software Technology2002，44，15： | 1 |
| 18 | Why don't all heavy snorers have obstructive sleep apnea显示文摘 | Polo O J Taftl M Fraga J | 1991 | Am Rev Respir Dis1991，143，6： | 1 |
| 19 | Ozonation of1,3,6-naphthalenetrisulphonic acid catalysed by activated car-bon in aqueous phase显示文摘 | RIVERA UTRILLA J SNCHEZ POLO M | 2002 | Applied Catalysis B:Environmental2002，39，4： | 1 |
| 20 | Sindbis virus DNA-based expression vectors utility for in vitro and in vivo gene transfer显示文摘 | Dubcnsky T W Driver D A Polo J M | 1996 | J Virol1996，70，： | 1 |
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