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| 1 | Poisoning of human DNA topoisomerase Ⅰ by ecteinascidin 743, an anti cancer drug that selectively aikyl, ates DNA in the minor groove显示文摘 | Takebayashi Y Pourquier P Yoshida A | 1999 | Proc Natl Acad Sci USA1999，96，13： | 1 |
| 2 | Topoisomerase poisoning activity of novel disaccharide anthracyclines显示文摘 | Pourquier P Tinelli S | 1999 | Mol Parmacol1999，56，1： | 1 |
| 3 | Gadd45,a p53-responsive stress protein,modifies DNA accessibility on damaged chromatin显示文摘 | CARRIER F GEORGEL P T POURQUIER P | 1999 | Mol Cell Biol1999，19，3： | 1 |
| 4 | Gadd45,a 53-responsive stress protein,modifies DNA accessibility on damaged chromatin显示文摘 | Carrier F Georgel P T Pourquier P | 1999 | Mol Cell Biol1999，19，3： | 1 |
| 5 | Topoisomerase Ⅰ-mediated DNA damage Adv显示文摘 | Pourquier P Pommier Y | 2001 | Cancer Res2001，80，： | 1 |
| 6 | Topoisomerase I inhibitors:selectivity and cellular resistance显示文摘 | Pommier Y Pourquier P Urasaki Y | 1999 | Drug Resist Updat1999，2，5： | 1 |
| 7 | Characteriza- tion of a novel topoisomerase I mutation from a camptothecin - re- sistant human prostate cancer cell line显示文摘 | URASAKI Y LACO G S POURQUIER P | 2001 | Cancer Res2001，61，5： | 1 |
| 8 | Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line显示文摘 | Urasaki Y Laco GS Pourquier P | 2001 | Cancer Res2001，61，5： | 1 |
| 9 | Anti-proliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair 显示文摘 | Takebayashi Y Pourquier P Zimonjic D B | 2001 | Nat Med2001，7，8： | 1 |
| 10 | Topoisomerase poisoning activity of novel disaccharide anthracyclines显示文摘 | Guano F Pourquier P Tinelli S | 1999 | Mol Pharmacol1999，56，1： | 1 |
| 11 | Characterization of a novel topoisomerase Imutation from a camp tothecin-resistant human prostate cancer cell line 显示文摘 | Urasaki Y Laco GS Pourquier P | 2001 | Cancer Res2001，61，5： | 1 |
| 12 | Targeting the genetic alterations of the PI3K-AKT-m TOR pathway:its potential use in the treatment of bladder cancers显示文摘 | HouédéN Pourquier P | 2015 | Pharmacol Ther2015，145，： | 1 |
| 13 | Trapping of mammalian topoisomerase 1 and recombinations in- duced by damaged DNA containing nicks or gaps, hn- portance of DNA end phosphorylation and camptothecin effects显示文摘 | Pourquier P Pilon AA Kohlhagen G | 1997 | J Biol Chem1997，，26： | 1 |
| 14 | Effects of modulators of multidrug resistance on the expression of the MDR1 gene on human KB cells in culture 显示文摘 | Hu YP Pourquier P Doignon F | 1996 | Anticancer Drugs1996，7，7： | 1 |
| 15 | Trapping of mammalian topoisomerase I and recombination induced by damaged DNA containing nicks or gaps, hnportance of DNA end phosphonrylation and camptothecin effects显示文摘 | Pourquier P Pilon AA Kohlhagen G | 1997 | J Biol Chem1997，272，26： | 1 |
| 16 | Characterization of a novel topoi-somerase I mutation from a camptothecin-resistant human prostate cancer cell line显示文摘 | Laco GS Pourquier P | 2001 | Cancer Res2001，61，5： | 1 |
| 17 | Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer ceil line显示文摘 | Urasaki Y Iaco GS Pourquier P | 2001 | Cancer Res2001，61，： | 1 |
| 18 | Mechanism of Action of Eukaryotic DNA Topoisomerase I and Drugs Targeted to tile Enzyme显示文摘 | Pommier Y Pourquier P Fan Y | 1998 | Biochim Biophys Acta1998，1400，13： | 1 |
| 19 | Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide excision repair显示文摘 | Takebayashi Y Pourquier P Popescu N | 2001 | Nat Med2001，7，8： | 1 |
| 20 | Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin 显示文摘 | Carrier F Georgel PT Pourquier P | 1999 | Mol CeU Biol1999，19，3： | 1 |
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