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| 1 | Severe scrub typhus infection: Clinical features, diagnostic challenges and management显示文摘Scrub typhus infection is an important cause of acute undifferentiated fever in South East Asia. The clinical picture is characterized by sudden onset fever with chills and non-specific symptoms that include headache, myalgia, sweating and vomiting. The presence of an eschar, in about half the patients with proven scrub typhus infection and usually seen in the axilla, groin or inguinal region, is characteristic of scrub typhus. Common laboratory findings are elevated liver transaminases, thrombocytopenia and leukocytosis. About a third of patients admitted to hospital with scrub typhus infection have evidence of organ dysfunction that may include respiratory failure, circulatory shock, mild renal or hepatic dysfunction, central nervous system involvement or hematological abnormalities. Since the symptoms and signs are non-specific and resemble other tropical infections like malaria, enteric fever, dengue or leptospirosis, appropriate laboratory tests are necessary to confirm diagnosis. Serological assays are the mainstay of diagnosis as they are easy to perform; the reference test is the indirect immunofluorescence assay(IFA) for the detection of Ig M antibodies. However in clinical practice, the enzyme-linked immuno-sorbent assay is done due to the ease of performing this test and a good sensitivity and sensitivity when compared with the IFA. Paired samples, obtained at least two weeks apart, demonstrating a ≥ 4 fold rise in titre, is necessary for confirmation of serologic diagnosis. The mainstay of treatment is the tetracycline group of antibiotics or chloramphenicol although macrolides are used alternatively. In mild cases, recovery is complete. In severe cases with multi-organ failure, mortality may be as high as 24%. | John Victor Peter Thomas I Sudarsan John Anthony J Prakash George M Varghese | 2015 | World Journal of Critical Care Medicine2015，4，3： | 13 |
| 2 | Rice bran proteins:properties and food use显示文摘 | Prakash J | 1996 | Critical Reviews in Food Science and Nutrition1996，36，6： | 1 |
| 3 | Isothermal and thermal cycling aging on IMC growth rate in lead-free and lead-based solder Interface显示文摘 | XU L H PANG J H L PRAKASH K H | 2005 | IEEE Transactions on Components and Packaging Technology2005，28，3： | 1 |
| 4 | Characterization of commercial Li-ion batteries using electrochemical-calorimetric measurements显示文摘 | HALLAJ S A PRAKASH J SELMAN J R | | 0，，： | 1 |
| 5 | Effect of ingredients on rheological,nutritional and quality characteristics of high protein,high fibre and low carbohydrate bread显示文摘 | DHINDA F LAKSHMI A J PRAKASH J | 2012 | Food and Bioprocess Technology2012，5，8： | 1 |
| 6 | A novel flame-retardant additive for lithium batteries 显示文摘 | LEE C W VENKATACHALAPATHY R PRAKASH J | 2000 | Electrochemical and Solid-State Letters2000，3，2： | 1 |
| 7 | Microsatellites in Malus X domestica(apple):abundance,polymorphism and cultivar identification 显示文摘 | Prakash S Zhu J M | 1997 | Theor Appl Genet1997，94，： | 1 |
| 8 | 显示文摘 | Joachin H Prakash J Liu J | 2007 | J Power Sources2007，163，： | 1 |
| 9 | Efficient analysis of aclass of microstrip antennas using the characteristic basisfunction method (CBFM) 显示文摘 | Yeo J Prakash V V S Mittra R | 2003 | Microwave and OpticalTechnology Letters2003，39，6： | 1 |
| 10 | In situ measurements of heat generation in a Li/mesocarbon microbead half-cell显示文摘 | LU W PRAKASH J | | 0，，3： | 1 |
| 11 | Acute kidney injury in late pregnancy in developing countries显示文摘 | Prakash J Niwas SS Parekh A | 2010 | Ren Fail2010，32，3： | 1 |
| 12 | Application of fine-grained tungsten carbide based cemented carbides显示文摘 | Prakash L J | 1995 | International Journal of Refractory & Hard Materials1995，13，5： | 1 |
| 13 | Surface acidity study of Mn ^+-montmorillonite clay catalysts by FT-IR spectroscopy: Correlation with esterification activity 显示文摘 | Reddy C R Nagendrappa G Prakash B S J | 2007 | Catal Commun2007，8，： | 1 |
| 14 | Isothermal and thermal cycling aging on IMC growth rate in lead-free and lead-based solder Interface 显示文摘 | Xu L H Pang J H L Prakash K H | 2005 | IEEE Transactions on Components Packaging and Manu- facturing Technology2005，，03： | 1 |
| 15 | Two new forms of gonadotropin-releasing hormone in a protochordate and the evolutionary implications显示文摘 | Powell J F Reska-Skiuner S M Prakash M O | | 0，，： | 1 |
| 16 | Postcataract endophthalmitis in South India incidence and outcome 显示文摘 | LALITHA P RAJAGOPALAN J PRAKASH K RAMASAMY K PRAJNA NV SRINIVASAN M | 2005 | Ophthalmology2005，112，11： | 1 |
| 17 | New cytotoxic lupane triterpenoids from the twigs of Coussarea paniculata 显示文摘 | Prakash C V S Schilling J K Johnson R K | 2003 | J Nat Prod2003，66，3： | 1 |
| 18 | Fluorine-containing reagents in organic synthesis显示文摘 | G A Olah J G Shih G K S Prakash | 1986 | J Fluorine Chem1986，33，14： | 1 |
| 19 | On the choice of importance distributions for unconstrained and constrained state es- timation using particle filter 显示文摘 | PRAKASH J PATWARDHAN S C SHAH S L | 2011 | Journal of Process Control2011，21，1： | 1 |
| 20 | Interruptions during the delivery of high-risk medications 显示文摘 | Trbovich P Prakash V Stewart J | 2010 | J Nurs Adm2010，40，5： | 1 |
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