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| 1 | Touch-down reverse transcriptase-PCR detection of IgV (H) rearrangement and Sybr-Green-based real-time RT-PCR quantitation of minimal residual disease in patients with chronic lymphocytic leukemia 显示文摘 | Pekova S Markova J Pajer P | 2005 | Mol Diagn2005，9，1： | 1 |
| 2 | Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat显示文摘 | Hausner T Pajer K Halat G | | 0，，02： | 1 |
| 3 | Neuropsychological function inadolescent girls with conduct disorder显示文摘 | Pajer K Chung J Leininger L | 2008 | J Am Acad Child AdolescPsychiatry2008，47，4： | 1 |
| 4 | The psychoneuroimmunology of postpartum de- pression显示文摘 | Corwin EJ Pajer K | 2008 | J Womens Health (Larehmt)2008，17，9： | 1 |
| 5 | Melanocyte fate in neural crest is triggered by Myb proteins through activation of c-kit显示文摘 | V. Karafiat M. Dvorakova P. Pajer V. Cermak M. Dvorak | 2007 | Cellular and Molecular Life Sciences2007，，22： | 1 |
| 6 | Adrenal androgen and gonad- al hormone levels in adolescent girls with conduct disorder 显示文摘 | Pajer K Tabbah R Gardner W | 2006 | Psychoneuroendocrinology2006，31，10： | 1 |
| 7 | Decreased cortisol levels in adolescent girls with conduct disorder显示文摘 | Pajer K Gardner W Rubin RT | 2001 | Arch Gen Psychiatry2001，58，3： | 1 |
| 8 | The molecularbackground of the differential UV absorbance of thehuman lens in the 240-400 nm range 显示文摘 | PAJER V TIBOLDI A BAE N | 2013 | Photochemis-try and Photobiology2013，89，4： | 1 |
| 9 | The leucine zipper region of Myb oncoprotein regulates the commitment of hematopoietic progenitors 显示文摘 | Karafiat V Dvorakova M Pajer P | 2001 | Blood2001，98，13： | 1 |
| 10 | Dendritic cell-based immuno- therapy induces transient clinical response in advanced rat fibrosar- coma-comparison with preventive anti-tumour vaccination 显示文摘 | Kucera A Pycha K Pajer P | 2009 | Folia Biol (Praha)2009，55，4： | 1 |
| 11 | P- sychoneuroimmunologic factors in inflammatory bowel dis- ease显示文摘 | MACKNER L M CLOUGH-PAABO E PAJER K | 2011 | Inilamm Bowel Dis2011，17，3： | 1 |
| 12 | The psychoneuroimmunology of postpartum depression显示文摘 | Corwin EJ Pajer K | 2008 | J Womens Health(Larchmt)2008，17，9： | 1 |
| 13 | Melanoeyte fate in neural crest is triggered by Myh proteins through activation of c-kit显示文摘 | Karafiat V Dvorakova M Pajer P | 2007 | Cellular and Molecular Life Sciences2007，64，29： | 1 |
| 14 | The leucine zipper region of Myb oncoprotein regulates the commitment of hematopoietic progenitors显示文摘 | Karafiat V Dvorakova M Pajer P | 2001 | Blood2001，98，13： | 1 |
| 15 | CpG methylation suppresses transcriptional activity of human syncytin-1 in non-placental tissues 显示文摘 | MATOUSKOVA M BLAZKOVA J PAJER P | 2006 | Exp Cell Res2006，312，7： | 1 |
| 16 | Women with antisocial behaviour:long-term health disability and helpseeking for emotional problems显示文摘 | Pajer K Stouthamer-Loeber M Gardner W Loeber R | 2006 | Crim Behav Ment Health2006，16，1： | 1 |
| 17 | Cardiovascular disease risk factors in adolescents:do negative emotions and hypothalamic-pituitary-adrenal axis function play a role显示文摘 | Pajer K A | 2007 | Curt Opin Pediatr2007，19，5： | 1 |
| 18 | Rosonance effects in low-loss ring waveguides显示文摘 | Haavisto J Pajer G A | 1980 | Optics Letters1980，5，2： | 1 |
| 19 | Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury显示文摘Efficient in vivo delivery of anti-inflammatory proteins to modulate the microenvironment of an injured spinal cord and promote neuroprotection and functional recovery is a great challenge.Nucleoside-modified messenger RNA(mRNA)has become a promising new modality that can be utilized for the safe and efficient delivery of therapeutic proteins.Here,we used lipid nanoparticle(LNP)-encapsulated human interleukin-10(hIL-10)-encoding nucleoside-modified mRNA to induce neuroprotection and functional recovery following rat spinal cord contusion injury.Intralesional administration of hIL-10 mRNA-LNP to rats led to a remarkable reduction of the microglia/macrophage reaction in the injured spinal segment and induced significant functional recovery compared to controls.Furthermore,hIL-10 mRNA treatment induced increased expression in tissue inhibitor of matrix metalloproteinase 1 and ciliary neurotrophic factor levels in the affected spinal segment indicating a time-delayed secondary effect of IL-105 d after injection.Our results suggest that treatment with nucleoside-modified mRNAs encoding neuroprotective factors is an effective strategy for spinal cord injury repair. | LászlóGál Tamás Bellák Annamária Marton Zoltán Fekécs Drew Weissman Dénes Török Rachana Biju Csaba Vizler Rebeka Kristóf Mitchell B.Beattie Paulo J.C.Lin Norbert Pardi Antal Nógrádi Krisztián Pajer | 2023 | Research2023，，4： | 0 |
| 20 | The mutual interaction between the host spinal cord and grafted undifferentiated stem cells fosters the production of a lesion-induced secretome显示文摘Pathophysiology of spinal cord injury:Injury to the spinal cord results in loss of gray and white matter i.e.,it produces a segmental spinal cord lesion and,as a consequence leads to a fatal loss of motor,sensory and autonomic functions.Spinal cord injuries in humans and other mammals are not followed by the replacement of lost neurons and oligodendrocytes and regrowth of injured axons,instead they lead to permanent,fatal and incurable functional deficits.The primary physical injury is followed by a cascade of tissue-decaying events,called secondary injury,which leads to ischemia,vascular disruption,neuroinflammation,excitotoxicity,demyelination and death of neurons and glial cells(Silva et al.,2014;Figure 1A).The direct mechanical disruption of the vasculature results in the increased permeability of the blood-spinal cord barrier.Due to the leakiness of blood-spinal cord barrier and production of cytokines by activated microglia,a number of various immune cells(T lymphocytes,neutrophils and monocytes)invade the injury site.The macrophages generate a set of inflammatory cytokines such as tumor necrosis factor-α,interleukin(IL)-1α,IL-1β,and IL-6,which may further augment the secondary events(Ahuja et al.,2017).In addition,a number of other disruptive processes contribute to the heterogeneous and time-sensitive pathophysiology of spinal cord injury. | Krisztián Pajer Tamás Bellák Antal Nógrádi | 2020 | Neural Regeneration Research2020，15，10： | 0 |
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