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| 1 | Chronic intestinal pseudo-obstruction显示文摘Chronic intestinal pseudo-obstruction (CIPO) is a se- vere digestive syndrome characterized by derangement of gut propulsive motility which resembles mechanical obstruction, in the absence of any obstructive process. Although uncommon in clinical practice, this syndrome represents one of the main causes of intestinal failure and is characterized by high morbidity and mortality. It may be idiopathic or secondary to a variety of diseases. Most cases are sporadic, even though familial forms with either dominant or recessive autosomal inheritance have been described. Based on histological features in- testinal pseudo-obstruction can be classified into three main categories:neuropathies, mesenchymopathies, and myopathies, according on the predominant involvement of enteric neurones, interstitial cells of Cajal or smooth muscle cells, respectively. Treatment of intestinal pseu- do-obstruction involves nutritional, pharmacological and surgical therapies, but it is often unsatisfactory and the long-term outcome is generally poor in the majority of cases. | Alexandra Antonucci Lucia Fronzoni Laura Cogliandro Rosanna F Cogliandro Carla Caputo Roberto De Giorgio Francesca Pallotti Giovanni Barbara Roberto Corinaldesi Vincenzo Stanghellini | 2008 | World Journal of Gastroenterology2008，14，19： | 12 |
| 2 | Long-term durable response to lenalidomide in a patient with hepatic epithelioid hemangioendothelioma显示文摘Epithelioid hemangioendothelioma(EH)is a rare tumor arising from the vascular endothelial cells of soft tissue or visceral organs.The most common visceral site is the liver,where it is often involved in a multifocal man-ner known as hepatic EH(HEH).Surgical resection with curative intent represents the gold standard therapy.When surgery is not feasible,or in cases of metastatic disease,no standard medical treatment is currently indicated.In small series,drugs with anti-angiogenic activity(such as bevacizumab,sorafenib,thalidomide,and lenalidomide)have been proposed with promising results.We describe a 73-year-old man with multifocal non-resectable HEH treated with lenalidomide.Disease status was evaluated by abdominal ultrasound and magnetic resonance every four months.The patient was treated for a total of 39 mo with prolonged disease stabilization and,at the time of writing,is still under treatment with a good tolerance profile.During a short period of treatment discontinuation,the disease showed slight progression that immediately resolved after the reintroduction of lenalidomide.Lenalidomide may represent a valid treatment option for HEH due to its anti-angiogenic and antineoplastic activities.This preliminary result merits further study in a large series. | Maria Caterina Pallotti Margherita Nannini Claudio Agostinelli Simona Leoni Valerio Di Scioscio Anna Mandrioli Cristian Lolli Maristella Saponara Stefano Pileri Luigi Bolondi Guido Biasco Maria Abbondanza Pantaleo | 2014 | World Journal of Gastroenterology2014，20，22： | 9 |
| 3 | Mucoepidermoid carci- noma of the sublingnal gland associated with Sjogren's syndrome 显示文摘 | Bombeccari GP Guzzi GPI Pallotti F | 2011 | Indian Cancer2011，48，3： | 1 |
| 4 | Rescue of mt-DNA deficiency causing Leber optic neuropathy 显示文摘 | Guy J Qi X Pallotti F | 2002 | Ann Neurol2002，52，： | 1 |
| 5 | Toll - like receptors in central nervous system injury and disease: a focus on the spinal cord 显示文摘 | Heiman A Pallottie A Heary RF | 2014 | Brain Behav Immun2014，42，： | 1 |
| 6 | Rescue of a mitochondrial deficiency causing Leber hereditary optic neuropathy显示文摘 | GUY J QI X P PALLOTTI F | 2002 | Ann Neurol2002，52，5： | 1 |
| 7 | Diagnostic and therapeutic aspects of iatrogenic hypoparathyroidism 显示文摘 | Pallotti F Seregni E Ferrari L | 2003 | Tumori2003，89，5： | 1 |
| 8 | An operational definition of the emergency criterion 显示文摘 | Pallotti G | 2007 | Applied Linguistics2007，28，3： | 1 |
| 9 | A downshift in temperature activates the high osmolarity glycerol ( HOG ) pathway, which determines freeze tolerance in Saccharomyces cerevisiae 显示文摘 | Panadero J Pallotti C Rodriguez-Vargas S | 2006 | J Biol Chem2006，281，8： | 1 |
| 10 | Pathological relevance of epithelial and mesenchymal phenotype plasticity 显示文摘 | Guarino M Micheli P Pallotti F | 1999 | Pathol Res Pract1999，195，6： | 1 |
| 11 | Evdence that specific mtDNA point mutatiom may not accumulate in skeletal muscle during normal human aging显示文摘 | PALLOTTI F CHEN X BONILLA E | 1996 | Am J Hum Genet1996，59，3： | 1 |
| 12 | A downshift in temperature activates the high osmolarity glycerol( HOG) pathway, which determines freeze toler-ance in Saccharomyces cerevisiae显示文摘 | PanaderoJ Pallotti C Rodriguez-Vargas S | 2006 | TheJournal of Biological Chemistry2006，281，2： | 1 |
| 13 | Postinfectious Irritable Bowel Syndrome显示文摘 | Giovanni Barbara Cesare Cremon Francesca Pallotti Roberto De Giorgio Vincenzo Stanghellini Roberto Corinaldesi | 2009 | Journal of Pediatric Gastroenterology and Nutrition2009，，： | 1 |
| 14 | Rescue of a mitochondrial deficiencycausing Leber hereditary optic neuropathy显示文摘 | Guy J Qi X Pallotti F Schon EA Manfredi G Carelli V | 2002 | Ann Neurol2002，52，5： | 1 |
| 15 | Structural characterization of nanoparticles-assembled titanium dioxide films produced by ultrafast laser ablation and deposition in background oxygen显示文摘 | S. Amoruso S. Tuzi D.K. Pallotti C. Aruta R. Bruzzese F. Chiarella R. Fittipaldi S. Lettieri P. Maddalena A. Sambri A. Vecchione X. Wang | 2013 | Applied Surface Science2013，，： | 1 |
| 16 | Pathological rel- evance of epithelial and mesenchymal phenotype plastic- ity 显示文摘 | Guarino M Micheli P Pallotti F | 1999 | Pathol Res Pract1999，195，： | 1 |
| 17 | Toll-like receptors in central nervous system injury and disease: A focus on the spinal cord 显示文摘 | Heiman A Pallottie A Heary RF | 2014 | Brain Behav Immun2014，42，： | 1 |
| 18 | Oral-esophageal lichen planus associated with oral squamous cell carcinoma显示文摘 | Bombeccari GP Pallotti F Guzzi G | 2008 | Indian J Dermatol Venereol Leprol2008，74，5： | 1 |
| 19 | Variation in the prevalence of enteropathogenic Yersinia in slaughter pigs from Belgium,Italy,and Spain显示文摘 | Martinez P O Fredriksson-Ahomaa M Pallotti A | 2011 | Foodborne Pathogens and Disease2011，8，3： | 1 |
| 20 | A Downshift in Temperature Activates the High Osmolarity Glycerol (HOG) Pathway,Which Determines Freeze Tolerance in Saccharomyces cerevisiae显示文摘 | Joaquín Panadero Claudia Pallotti Sonia Rodríguez-Vargas | 2006 | The Journal of Biological Chemistry2006，281，8： | 1 |
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