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| 1 | Critical analysis of the literature investigating urogenital function preservation following robotic rectal cancer surgery显示文摘AIM To analyses the current literature regarding the urogenital functional outcomes of patients receiving robotic rectal cancer surgery. METHODS A comprehensive literature search of electronic databases was performed in October 2015. The following search terms were applied: 'rectal cancer' or 'colorectal cancer' and robot* or 'da Vinci' and sexual or urolog* or urinary or erect* or ejaculat* or impot* or incontinence. All original studies examining the urological and/or sexual outcomes of male and/or female patients receiving robotic rectal cancer surgery were included. Reference lists of all retrieved articles were manually searched for further relevant articles. Abstracts were independently searched by two authors. RESULTS Fifteen original studies fulfilled the inclusion criteria. A total of 1338 patients were included; 818 received robotic, 498 laparoscopic and 22 open rectal cancer surgery. Only 726(54%) patients had their urogenital function assessed via means of validated functional questionnaires. From the included studies, three found that robotic rectal cancer surgery leads to quicker recovery of male urological function and five of male sexual function as compared to laparoscopic surgery. It is unclear whether robotic surgery offers favourable urogenital outcomes in the long run for males. In female patients only two studies assessed urological and threesexual function independently to that of males. In these studies there was no difference identified between patients receiving robotic and laparoscopic rectal cancer surgery. However, in females the presented evidence was very limited making it impossible to draw any substantial conclusions. CONCLUSION There seems to be a trend towards earlier recovery of male urogenital function following robotic surgery. To evaluate this further, larger well designed studies are required. | Sofoklis Panteleimonitis Jamil Ahmed Mick Harper Amjad Parvaiz | 2016 | World Journal of Gastrointestinal Surgery2016，8，11： | 7 |
| 2 | Robotic rectal cancer surgery:Results from a European multicentre case series of 240 resections and comparative analysis between cases performed with the da Vinci Si and Xi systems显示文摘Introduction:Robotic systems are designed to address the limitations of laparoscopic surgery,leading to a growing interest in robotic rectal surgery.However,certain technical limitations associated with the previous systems(da Vinci S&Si)have arguably slowed down its wholesale adoption.The latest robotic platform,the da Vinci Xi,addresses these limitations.This study aims to examine the short-term surgical outcomes of 240 single-docking fully-robotic rectal cancer resections and compare the outcomes of cases performed with the da Vinci Xi vs Si systems.Materials and methods:All consecutive patients receiving robotic rectal cancer resections from three centres between 2013 and 2018 were identified from prospectively collated databases.The baseline characteristics and short-term surgical outcomes are presented and the da Vinci Xi vs Si system outcomes are analysed.Results:A total of 240 patients were identified(124 Si,116 Xi).Median operation-time and length-of-stay were 260 minutes and 6 days respectively.Conversion and 30-day mortality rates were 0.The da Vinci Si vs Xi system analysis shows that operation-time was lower in the Si group(230 vs 300 min,p=0.000)but length-of-stay,lymph node yield and circumferential resection margin favoured the Xi group(7 vs 5 days,p=0.010;17 vs 21,p=0.000;92.7%vs 99.1%,p=0.020).Conclusion:Single-docking fully-robotic rectal cancer surgery is safe,feasible and can lead to good shortterm outcomes,making it a good alternative to laparoscopic rectal cancer surgery.The new systems technological advances may result in better short-term outcomes but further larger scale observational studies are required if we are to reach such a conclusion. | Sofoklis Panteleimonitis Oliver Pickering Mukhtar Ahmad Mick Harper Tahseen Qureshi Nuno Figueiredo Amjad Parvaiz | 2020 | Laparoscopic, Endoscopic and Robotic Surgery2020，3，1： | 5 |
| 3 | Concomitant gastric adenocarcinoma and stromal tumor in a woman with polymyalgia rheumatica显示文摘胃肠的基质肿瘤(大意) 是胃肠道的稀罕的瘤(1%) ,到我们的知识,胃的癌和大意的同步表示的仅仅稀罕的案例在文学被汇报。有胃的腺癌和大意的一个同时的演讲的 72 岁的女性被介绍。而且,由于多肌痛风湿病一病人作为治疗收到了 corticosteroids 最后 3 年。这些瘤的伴随物出现可以包含普通致癌因素,能有有多肌痛的一个协会风湿病任何一个作为帕拉肿瘤的表示或由于它有 corticosteroids 的治疗。 | Panteleimon Kountourakis Niki Arnogiannaki Ilias Stavrinides Nikiforos Apostolikas Gerasimos Rigatos | 2008 | World Journal of Gastroenterology2008，14，43： | 3 |
| 4 | Update on the association of hepatitis B with intrahepatic cholangiocarcinoma:Is there new evidence?显示文摘Intrahepatic cholangiocarcinoma(iCCA)is a subgroup of cholangiocarcinoma that accounts for about 10%-20%of the total cases.Infection with hepatitis B virus(HBV)is one of the most important predisposing factors leading to the formation of iCCA.It has been recently estimated based on abundant epidemiological data that the association between HBV infection and iCCA is strong with an odds ratio of about 4.5.The HBV-associated mechanisms that lead to iCCA are under intense investigation.The diagnosis of iCCA in the context of chronic liver disease is challenging and often requires histological confirmation to distinguish from hepatocellular carcinoma.It is currently unclear whether antiviral treatment for HBV can decrease the incidence of iCCA.In terms of management,surgical resection remains the mainstay of treatment.There is a need for effective treatment modalities beyond resection in both first-and second-line treatment.In this review,we summarize the epidemiological evidence that links the two entities,discuss the pathogenesis of HBV-associated iCCA,and present the available data on the diagnosis and management of this cancer. | Nikolaos Fragkou Lazaros Sideras Panteleimon Panas Christos Emmanouilides Emmanouil Sinakos | 2021 | World Journal of Gastroenterology2021，27，27： | 2 |
| 5 | Antihypertensive therapy and the risk of new-onset diabetes显示文摘 | PANTELEIMON A SARAFLDIS GEORGE L | 2006 | Diabetes Care2006，29，： | 1 |
| 6 | Some like it vigorous: measuring individual differences in the preference for and tolerance of exercise intensity显示文摘 | Panteleimon Ekkekakis Eric E Hall Steven J Petruzzello | 2005 | Journal of Sport & Exercise Psychology2005，27，： | 1 |
| 7 | Neoadjuvant sequential epirubicin and docetaxel followed by surgery-radiotherapy and post-operative docetaxel or gemcitabine/vinorelbine combination based on primary response:a multimodality approach for locally advanced breast cancer显示文摘 | Panteleimon Kountorakis Ioannis Missitzis Dimitrios Doufexis | 2011 | J Cancer Res Clin Oncol2011，137，： | 1 |
| 8 | Can Public Health Take the HIT? High-Intensity Interval Training and Affect in Obese Women显示文摘 | Decker ES Panteleimon Ekkekakis | 2012 | Med Sci Sports Exerc2012，44，5： | 1 |
| 9 | Assessing the cognitive impact of Alzheimer disease pathology and vascular burden in the aging brain: the Geneva experience显示文摘 | Panteleimon Giannakopoulos Gabriel Gold Enik? K?vari Armin Gunten Anouk Imhof Constantin Bouras Patrick R. Hof | 2007 | Acta Neuropathologica2007，，1： | 1 |
| 10 | Antihypertensive therapy and the Risk of New-Onset Diabetes显示文摘 | Panteleimon A Sarafidi S George L | | 0，，05： | 1 |
| 11 | Open Abdomen with Concomitant Entero-Atmospheric Fistula: Attempt to Rationalize the Approach to a Surgical Nightmare and Proposal of a Clinical Algorithm显示文摘 | Salomone Di Saverio Antonio Tarasconi Kenji Inaba Pradeep Navsaria Federico Coccolini David Costa Navarro Matteo Mandrioli Panteleimon Vassiliu Elio Jovine Fausto Catena Gregorio Tugnoli | 2014 | Journal of the American College of Surgeons2014，，： | 1 |
| 12 | Antihypertensive therapy and the risk of New-Onset Diabetes 显示文摘 | Panteleimon A Sarafidi S George L | 2006 | J Diabetes Care2006，29，5： | 1 |
| 13 | Prognostic significance of HER3 and HER4 protein expression in colorectal adenocarcinomas显示文摘 | Panteleimon K Kitty P Amanda P | | 0，，06： | 1 |
| 14 | Practical markers of the transition from aerobic to anaerobic metabolism during exercise: rationale and a case for affect-based exercise prescription显示文摘 | Panteleimon Ekkekakis Eric E Hall Steven J Petruzzello | 2003 | Preventive Medicine2003，，2： | 1 |
| 15 | Stem cell dynamics in the hair follicle niche显示文摘 | Panteleimon R Valentina G | 2014 | Semin Cell Dev Biol2014，30，1： | 1 |
| 16 | Can the Study of Natural Vegetation Succession Assist in the Control of Soil Erosion on Abandoned Croplands on the Loess Plateau 显示文摘 | JUYING JIAO JOSEPH TZANOPOULOS PANTELEIMON XOFIS | 2007 | Restoration Ecology2007，15，3： | 1 |
| 17 | Affect and prefrontal hemodynamics during exercise under immersive audiovisual stimulation:Improving the experience of exercise for overweight adults显示文摘Objective:Research on methods of improving the affective experience of exercise remains limited,especially for low-active overweight adults.We investigated the effectiveness of a virtual-reality headset and headphones in improving affective responses over conventionally delivered audiovisual stimulation.Methods:Low-active,overweight adults(16 women,5 men;age:34.67±9.62 years;body mass index:28.56±4.95 kg/m^2;peak oxygen uptake for men:29.14±6.56 mL/kg/min,for women:22.67±4.52 mL/kg/min,mean±SD)completed 15-min sessions of recumbent cycling at the ventilatory threshold:(a)high immersion(HI,virtual reality headset and headphones),(b)low immersion(LI,television screen and speakers),and(c)Control.During-exercise pleasure and post-exercise enj oyment were self-reported.Oxygenation of the right dorsolateral pre frontal cortex(dIPFC)was assessed with near infrared spectroscopy.Results:Higher pleasure was reported during HI than during LI and Control(Condition×Time interaction;p<0.001,ηp^2=0.43).Participants who reported a preference for low exercise intensity showed higher dIPFC oxygenation during Control,but this difference diminished during LI and HI(Condition×Time×Preference interaction;p=0.036,ηp^2=0.10).Conclusion:Compared with conventionally delivered audiovisual stimulation,using a virtual-reality headset strengthens the dissociative effect,further improving affective responses to exercise at the ventilatory threshold among overweight,low-active adults.Presumably by competing with interoceptive afferents at the level of sensory input,audiovisual stimulation may lessen reliance on cognitive efforts to attenuate declining affect,as indicated by lower right dIPFC activity,particularly among participants disinclined toward high exercise intensity. | Leighton Jones Panteleimon Ekkekakis | 2019 | Journal of Sport and Health Science2019，8，4： | 0 |
| 18 | Advances in molecular,genetic and immune signatures of gastric cancer:Are we ready to apply them in our patients' decision making?显示文摘In the last few years we have witnessed a vast expansion of our knowledge regarding the molecular and genetic profile of gastric cancer.The molecular subtypes described have shed light on the pathogenesis of the disease,thus prompting the development of new therapeutic strategies and favoring a more individualized approach for treatment.Most of the clinical trials for so called targeted therapies could be considered,at best,partially successful.In addition,checkpoint inhibitors ha-ve recently been added to our armamentarium in later stages of the disease,and combinations with chemotherapy and targeted agents are currently under development.In view of the rapid advances of molecular oncology,a new challenge for the clinical oncologist arises: The appropriate patient selection for each new therapy,which can be made possible only through the implementation of predictive biomarkers in our therapy decision making. | Stavros Gkolfinopoulos Demetris Papamichael Konstantinos Papadimitriou Panos Papanastasopoulos Vassilios Vassiliou Panteleimon Kountourakis | 2018 | World Journal of Gastrointestinal Oncology2018，10，7： | 0 |
| 19 | Leptomeningeal metastases originated from esophagogastric junction/gastric cancer:A brief report of two cases显示文摘Leptomeningeal carcinomatosis is a very rare manifestation in patients diagnosed with esophagogastric junction and gastric cancer. Its prognosis is ominous and therapy outcomes are disappointing. Herein, we present two patients; one initially diagnosed with gastric cancer and leptomeningeal carcinomatosis but no other evidence of metastatic disease and the other one initially diagnosed with esophagogastric junction cancer, who recurred solitary with leptomeningeal seedings several years after the initial diagnosis and treatment. Furthermore, a thorough and short review of the literature is carried out. | Panteleimon Kountourakis Demetris Papamichael Haris Haralambous Michael Michael Georgios Nakos Sylvia Lazaridou Eleni Fotiou Vassilios Vassiliou Demetrios Andreopoulos | 2018 | World Journal of Gastrointestinal Oncology2018，10，1： | 0 |
| 20 | Chromogranin A as a valid marker in oncology: Clinical application or false hopes?显示文摘Chromogranin A, due to its primary expression throughout the neuroendocrine system, is a widely accepted biomarker for the assessment of neuro-endocrine tumors. It has been traditionally used in the management of patients with tumors of gastro-enteropancreatic origin. Lately, it has also been implicated in various conditions and diseases, both benign and malignant. However, the paucity of data of adequate strength, as well as its relation with common physiologic conditions and its interaction with commonly prescribed medications, limit its clinical use in only a narrow spectrum. Herein, we present a thorough review to the most frequent conditions where its levels are affected, focusing specifically on its potential use as a prognostic and predictive biomarker in oncology. | Stavros Gkolfinopoulos Konstantinos Tsapakidis Konstantinos Papadimitriou Demetris Papamichael Panteleimon Kountourakis | 2017 | World Journal of Methodology2017，7，1： | 0 |
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