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4篇 您的检索式:作者名="Paola Perego"
    题名 作者 年代 出处 被引量
1Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks显示文摘Giacomo Buscemi Paola Perego Nives Carenini 2004Oncogene2004,,:1
2Highly tumorigenic lung cancer CD133 + cells display stem-like features and are spared by cisplatin treatment显示文摘Giulia Bertolini Luca Roz Paola Perego 2009PNAS2009,106,16:1
3Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment显示文摘Bertolini Luca Roz Paola Perego 2009Proc Natl Acad Sci USA2009,106,16:1
4Tackling cisplatin resistance in ovarian cancer: what can we do?显示文摘Ovarian cancer is a complex disease mainly consisting of epithelial cancer which comprises various histological subtypes.The most frequent one is high-grade serous ovarian carcinoma.The prognosis of this disease is poor because most women are diagnosed with advanced disease.Although many patients respond to first-line Pt-based therapy,the development of resistance limits the efficacy of therapy.Novel therapeutic strategies to improve the efficacy of ovarian carcinoma treatment are emerging from both basic and translational research efforts.In this Special Issue,approaches to improve the armamentarium to fight ovarian carcinoma are presented,thereby providing an overview of selected aspects of ovarian cancer biology that can be exploited to improve treatment.In this context,a re-evaluation and optimization of already tested strategies such as intra-peritoneal therapy together with a deep investigation of the recently acquired knowledge on factors(e.g.,E3 ubiquitin ligases)and features[Cancer Stem Cells(CSCs)]contributing to drug resistance may provide useful insights to tackle cisplatin resistance.Paola Perego 2021Cancer Drug Resistance2021,4,4:0
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