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| 1 | Hepatitis C virus infection and thyroid autoimmunedisorders:A model of interactions between the host and theenvironment显示文摘The hepatitis C virus(HCV) infection is an important public health problem and it is associated with hepatic and extrahepatic manifestations. Autoimmune thyroid diseases are common in HCV infected patients and the standard interferon-based treatment is associated with an increase of the immune-mediated thyroid damage. Recent evidence in the literature analyzed critical points of the mechanisms of thyroid damage, focusing on the balance between the two sides of the interaction: The environment(virus infection with potential crossreaction) and the host(susceptibility genes with consistent immune response). The spectrum of antiviral treatment for chronic HCV infection is rapidly expanding for the development of dual o triple therapy. The availability of interferon-free combined treatment with direct antiviral agents for HCV is very promising, in order to ameliorate the patient compliance and to reduce the development of thyroid autoimmunity. | francesca pastore antonio martocchia manuela stefanelli pietro prunas stefania giordano lavinia toussan antonio devito paolo falaschi | 2016 | World Journal of Hepatology2016，8，2： | 12 |
| 2 | Occurrence of PAH in the seasonal snowpack of the Eastern Italian Alps显示文摘 | Jacopo Gabrieli Fabio Decet Alberto Luchetta Mauro Valt Paolo Pastore Carlo Barbante | 2010 | Environmental Pollution2010，，10： | 1 |
| 3 | Differential modulation of stress-inflammation responses by plant polyphenols in cultured normal human keratinocytes and immortalized HaCaT cells显示文摘 | Saveria Pastore Daniela Lulli Alla I. Potapovich Paolo Fidanza Vladimir A. Kostyuk Elena Dellambra Chiara De Luca Riccardo Maurelli Liudmila G. Korkina | 2011 | Journal of Dermatological Science2011，，2： | 1 |
| 4 | Description and validation of an analytical method for the determination of paromomycin sulfate in medicated animal feeds显示文摘 | Paolo Pastore Albino Gallina Franco Magno | 2000 | Analyst2000，，125： | 1 |
| 5 | Intraduodenal Lipase Activity in Celiac Disease Assessed by Means of 13C Mixed-Triglyceride Breath Test显示文摘 | Francesco Perri Maria Pastore Virginia Festa Rocco Clemente Michele Quitadamo Mario R. D’Altilia Grazia Niro Paolo Paolucci Angelo Andriulli | 1998 | Journal of Pediatric Gastroenterology & Nutrition1998，，4： | 1 |
| 6 | Diagnosis of hepatic glycogenosis in poorly controlled type 1 diabetes mellitus显示文摘Hepatic glycogenosis(HG) in type 1 diabetes is a underrecognized complication. Mauriac firstly described the syndrome characterized by hepatomegaly with altered liver enzymes, growth impairment, delay puberty and Cushingoid features, during childhood. HG in adulthood is characterized by the liver disorder(with circulating aminotransferase increase) in the presence of poor glycemic control(elevation of glycated hemoglobin, Hb A1 c levels). The advances in the comprehension of the metabolic pathways driving to the hepatic glycogen deposition point out the role of glucose transporters and insulin mediated activations of glucokinase and glycogen synthase, with inhibition of glucose-6-phosphatase. The differential diagnosis of HG consists in the exclusion of causes of liver damage(infectious, metabolic, obstructive and autoimmune disease). The imaging study(ultrasonography and/or radiological examinations) gives information about the liver alterations(hepatomegaly), but the diagnosis needs to be confirmed by the liver biopsy. The main treatment of HG is the amelioration of glycemic control that is usu-ally accompanied by the reversal of the liver disorder. In selected cases, more aggressive treatment options(transplantation) have been successfully reported. | Stefania Giordano Antonio Martocchia Lavinia Toussan Manuela Stefanelli Francesca Pastore Antonio Devito Marcello G Risicato Luigi Ruco Paolo Falaschi | 2014 | World Journal of Diabetes2014，5，6： | 1 |
| 7 | Epidemiological, clinical and therapeutic evaluation of the Italian cholera epidemic in 1994显示文摘 | Paolo Maggi Sergio Carbonara Cecilia Fico Teresa Santantonio Chiara Romanelli Emanuele Sforza Giuseppe Pastore | 1997 | European Journal of Epidemiology1997，，1： | 1 |
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