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| 1 | Retinopathy of prematurity: Past, present and future显示文摘Retinopathy of prematurity(ROP) is a vasoproliferative disorder of the retina occurring principally in new born preterm infants. It is an avoidable cause of childhood blindness. With the increase in the survival of preterm babies, ROP has become the leading cause of preventable childhood blindness throughout the world. A simple screening test done within a few weeks after birth by an ophthalmologist can avoid this preventable blindness. Although screening guidelines and protocols are strictly followed in the developed nations, it lacks in developing economies like India and China, which have the highest number of preterm deliveries in the world. The burden of this blindness in these countries is set to increase tremendously in the future, if corrective steps are not taken immediately. ROP first emerged in 1940 s and 1950 s, when it was called retrolental fibroplasia. Several epidemics of this disease were and are still occurring in different regions of the world and since then a lot of research has been done on this disease. However, till date very few comprehensive review articles covering all the aspects of ROP are published. This review highlights the past, present and future strategies in managing this disease. It would help the pediatricians to update their current knowledge on ROP. | Parag K Shah Vishma Prabhu Smita S Karandikar Ratnesh Ranjan Venkatapathy Narendran Narendran Kalpana | 2016 | World Journal of Clinical Pediatrics2016,5,1: | 13 |
| 2 | Predictors for perioperative blood transfusion in elderly patients with extra capsular hip fractures treated with cephalo-medullary nailing显示文摘我们的学习的 PurposeThe 目的是在老病人为 perioperative 输血决定预兆的因素和要求,额外的胶囊的新潮的破裂与 cephalo 髓的 device.MethodsSeventy 对待 -- 有与 cephalo 髓的钉对待的额外的胶囊的新潮的破裂的九个病人在学习被包括。年龄,性别, ASA 等级,外科,外科手术前、手术后的血色素,一些医院停留,骨折类型,输的单位的数字和 30 天的死亡预定 recorded.ResultsThe 平均数年龄是 82.3 年。47 个病人经历了一根短钉子和 32 个病人一根长钉子;53.4% 病人手术后地要求了输血。输送在71.8%长钉子被要求( p ? 0.05 ),在 80 岁上面的65.8%病人( p ? 0.05 ),有低于 90 的血红素的病人的100%?有 ASA 的 g/L 和 20 个病人 3 分级( p ? 0.05 )。有 A2 的 78.5% 病人断裂并且 75% A3 破裂需要输血(p ?>? 0.05 ) 。一些在非输送组的医院停留是 13 天,在输送,组是 19 天(p ? 0.05 ) 。55.1% 在 36 以内操作了 ? h 并且 47.6% 在 36 以后操作了 ? 承认的 h 需要输送(p ?>? 0.05 ) 。在需要输血的病人的三十天的死亡是5%,在非输送,组是3.7%( p ?>? 0.05 ) .ConclusionPatient 年龄, ASA 等级,钉子的外科手术前的血色素和长度是为在在与cephalo髓的钉对待的老病人的额外的胶囊的新潮的破裂的 perioperative 输血的可靠预言者并且增强一条选择输送政策。 | M, All Fazal Caroline Bagley Parag Garg | 2018 | Chinese Journal of Traumatology2018,21,1: | 4 |
| 3 | Economical effect of lumen apposing metal stents for treating benign foregut strictures显示文摘AIM To evaluate the clinical and economical efficacy of lumen apposing metal stent(LAMS) in the treatment of benign foregut strictures.METHODS A single center retrospective database of patients who underwent endoscopic treatment of benign foregut strictures between January 2014 and May 2017 was analyzed. A control group of non-stented patients who underwent three endoscopic dilations was compared to patients who underwent LAMS placement. Statistical tests performed included independent t-tests and fiveparameter regression analysis RESULTS Nine hundred and ninety-eight foregut endoscopic dilations were performed between January 2014 and May 2017. 15 patients underwent endoscopic LAMS placement for treatment of benign foregut stricture. Thirty-six patients with recurrent benign foregut strictures underwent three or more endoscopic dilations without stent placement. The cost ratio of endoscopic dilation to LAMS(stent, placement and retrieval) is 5.77. Cost effective analysis demonstrated LAMS to be economical after three endoscopic dilation overall.LAMS was cost effective after two dilations in the Postsurgical stricture subgroup. CONCLUSION Endoscopists should consider LAMS for the treatment of benign foregut strictures if symptoms persist past three endoscopic dilations. Post-surgical strictures may benefit from LAMS if symptoms persist after two dilations in a post-surgical. Early intervention with LAMS appears to be a clinically and economically viable option for durable symptomatic relief in patients with these strictures. | Alexander Hallac Wichit Srikureja Eashen Liu Parag Dhumal Ashish Thatte Nishant Puri | 2018 | World Journal of Gastrointestinal Endoscopy2018,10,10: | 3 |
| 4 | Role of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in cryoballoon ablation outcomes for paroxysmal atrial fibrillation显示文摘BACKGROUND Cryoballoon ablation(CBA)is recommended for patients with paroxysmal atrial fibrillation(AF)refractory to antiarrhythmic drugs.However,only 80%of patients benefit from initial CBA.There is growing evidence that pretreatment with angiotensin-converting enzyme inhibitors(ACEIs)and angiotensin receptor blockers(ARBs)decreases the recurrence of AF postablation,particularly in nonparoxysmal AF undergoing radiofrequency ablation.The role of ACEIs and ARBs in patients with paroxysmal AF in CBA remains unknown.We decided to investigate the role of ACEIs and ARBs in preventing the recurrence of atrial arrhythmia(AA)following CBA for paroxysmal AF.AIM To investigate the role of ACEIs and ARBs in preventing recurrence of AA following CBA for paroxysmal AF.METHODS We followed 103 patients(age 60.6±9.1 years,29%women)with paroxysmal AF undergoing CBA 1-year post procedure.Recurrence was assessed by documented AA on electrocardiogram or any form of long-term cardiac rhythm monitoring.A multivariable Cox proportional hazard model was used to assess if ACEI or ARB treatment predicted the risk of AA recurrence.RESULTS After a 1-year follow-up,19(18.4%)participants developed recurrence of AA.Use of ACEI or ARB therapy was noted in the study population.Patients on ACEI/ARB had a greater prevalence of hypertension and coronary artery disease.On a multivariate model adjusted for baseline demographics and risk factors for AF,ACEI or ARB therapy did not prevent recurrence of AA following CBA(P=0.72).Similarly,on Kaplan–Meier analysis pretreatment with ACEI/ARB did not predict the time to first recurrence of AA(P=0.2173).CONCLUSION In our study population,preablation treatment with an ACEI or ARB had no influence on the recurrence of AA following CBA for paroxysmal AF. | Ibragim Al-Seykal Abhishek Bose Parag A Chevli Zeba Hashmath Nitish Sharma Ajay K Mishra Douglas Laidlaw | 2022 | World Journal of Cardiology2022,14,10: | 2 |
| 5 | Acute exacerbation and reactivation of chronic hepatitis C virus infection in cancer patients显示文摘 | Parag Mahale Dimitrios P. Kontoyiannis Roy F. Chemaly Ying Jiang Jessica P. Hwang Marta Davila Harrys A. Torres | 2012 | Journal of Hepatology2012,,6: | 2 |
| 6 | Is myopia a protective factor against central serous chorioretinopathy?显示文摘AIM: To evaluate if any association exists between central serous chorioretinopathy(CSCR) and the refractive status of the eye.· METHODS: This retrospective, institutional, case control study included 499 patients, wherein 262 patients diagnosed as acute CSCR, were compared with an age and gender matched control group of 237 patients. All patients were evaluated with a detailed systemic and ocular history, objective and subjective refractions for both eyes and complete ocular examination by a retina specialist, at all visits. Optical coherence tomography confirmed the diagnosis of CSCR.·RESULTS: The mean age was found to be 40±7y in the study group(Group 1) compared to 38±10y in the control group(Group 2). Most common refractive status in the study group, was emmetropia seen in 191 patients(72.9%), followed by hypermetropia seen in 47 patients(17.9%) and astigmatism seen in 21 patients(8.0%). Only3 subjects(1.1%) had myopia, which was less than or equal to 1.0 D, compared to 70 subjects(29.5%) in the control group, suggesting a statistically significant lower incidence of CSCR among the myopic patients(P <0.0001). With respect to the systemic factors, 26(9.9%)patients were using systemic steroids in the study group(Group 1) compared to none in the control group(Group 2)suggesting a statistically significant association of CSCR with systemic steroid use(P <0.05). No other significant systemic risk factors were noted.· CONCLUSION: Though CSCR is a multifactorial disease, myopia serves as a protective factor for CSCR.Thus, myopic eyes are less likely to develop CSCR.Since both retinal pigment epithelium(RPE) and choriocapillaris are postulated in the pathogenesis of CSCR, chorio-retinal thinning and atrophy seen in myopic eyes are less likely to cause CSCR. | George J.Manayath Saurabh Arora Hardik Parikh Parag K.Shah Sarvesh Tiwari Venkatapathy Narendran | 2016 | International Journal of Ophthalmology(English edition)2016,9,2: | 2 |
| 7 | Comparison of artificial neural network (ANN) and response surface methodology (RSM) in fermentation media optimization: Case study of fermentative production of scleroglucan显示文摘 | Kiran M. Desai Shrikant A. Survase Parag S. Saudagar S.S. Lele Rekha S. Singhal | 2008 | Biochemical Engineering Journal2008,,3: | 2 |
| 8 | Clinical profile and outcomes of pediatric endogenous endophthalmitis: A report of 11 cases from South India显示文摘AIM To study the clinical profile and outcomes of pediatric endogenous endophthalmitis from a tertiary eye hospital in South India.METHODS A total of 13 eyes of 11 children presented to us with varied symptoms and presentations of endogenous endophthalmitis, over a five-year period from January 2010 to December 2015 were studied. Except for two eyes of a patient, vitreous aspirates were cultured from all 11 eyes to isolate the causative organism. These eleven eyes also received intravitreal injections. All patients were treated with systemic antibiotics. RESULTS Two cases had bilateral endophthalmitis. Ages ranged from 4 d to 11 years. Five cases were undiagnosed and treated, before being referred to our center. Ten of the 13 eyes underwent a core vitrectomy. The vitrectomy was done at an average on the second day after presenting(range 0-20 d). Five of the 11 vitreous aspirates showed isolates. The incriminating organisms were bacteria in three and fungus in two. An underlying predisposing factor was found in seven patients. At a mean follow-up 21.5 mo, outcome was good in 7 eyes of 6 cases(54%), five eyes of four cases(38%) ended up with phthisis bulbi while one child died of systemic complications. CONCLUSION Endogenous endophthalmitis is a challenge for ophtha-lmologists. Early diagnosis and intervention is the key for a better outcome. | Gayatri Murugan Parag K Shah Venkatapathy Narendran | 2016 | World Journal of Clinical Pediatrics2016,5,4: | 2 |
| 9 | Cavitation:an Auxiliary Technique in Wastewater Treatment Schemes显示文摘 | PARAG R G | 2002 | Advances in Environmental Research2002,,6: | 1 |
| 10 | A review of imperative tcchnologies for wastewater treatment I : oxidation technologies at ambient conditions显示文摘 | Parag R G Aniruddha B P | 2004 | Advances in Environmental Research2004,8,: | 1 |
| 11 | A review of imperative technologies for wastewater treatment I : oxidation technologies at ambient conditions 显示文摘 | Cogate Parag R Pandit Aniruddha B | 2004 | Advances in Environmental Research2004,8,34: | 1 |
| 12 | De gradation of pnitrophenol using acoustic cavitation and Fenton chemistry 显示文摘 | A mey A Pradhan Parag R Gogate | 2010 | Journal of Haz- ardous Materials2010,173,13: | 1 |
| 13 | A review of imperative technologies for wastewater treatment Ⅱ: hybrid methods显示文摘 | Parag R Gogate Aniruddha B Pandit | 2004 | Ad- vanced in Environmental Research2004,,8: | 1 |
| 14 | Antimicrobial Activity of Curcumin against Helicobacter pylori Isolates fromIndia and during Infections in Mice显示文摘 | Ronita De Parag Kundu | | 0,,04: | 1 |
| 15 | Treatment of cyanide containing wastewater using cavitation based approach显示文摘 | Rajashree H J Parag R G | 2014 | Ultrason Sonochem2014,21,4: | 1 |
| 16 | Most patients with HCV ‐associated lymphoma present with mild liver disease: a call to revise antiviral treatment prioritization显示文摘 | Harrys A. Torres Parag Mahale | 2015 | Liver Int2015,,6: | 1 |
| 17 | Frequency of depression after stroke : a systematic review of observational studies显示文摘 | Hackett ML Yapa C Parag V | 2005 | Stroke2005,36,: | 1 |
| 18 | An Empirical Study of Impact of Crossover Operators on the Performance of Non-binary Genetic Algorithm based Neural Approaches for Classi cation 显示文摘 | Parag C P James A R | 2004 | Computers Operations Research2004,31,6: | 1 |
| 19 | Stent-Graft Treatment of Patients with Acute Bleeding from Hepatic Artery Branches显示文摘 | Parag Rami David Williams Andrew Forauer Wojciech Cwikiel | 2005 | CardioVascular and Interventional Radiology2005,,2: | 1 |
| 20 | Experimental investigation of burning rates of pure ethanol and ethanol blended fuels 显示文摘 | Parag S Raghavan V | 2009 | Combustion and Flame2009,156,5: | 1 |