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| 1 | WJSC 6^(th) Anniversary Special Issues(1):Hematopoietic stem cell transplantation Allogeneic hematopoietic cell transplant for acute myeloid leukemia:Current state in 2013 and future directions显示文摘Acute myeloid leukemia(AML)represents a heterogeneous group of high-grade myeloid neoplasms of the elderly with variable outcomes.Though remissioninduction is an important first step in the management of AML,additional treatment strategies are essential to ensure long-term disease-free survival.Recent pivotal advances in understanding the genetics and molecular biology of AML have allowed for a risk-adapted approach in its management based on relapse-risk.Allogeneic hematopoietic cell transplantation(allo-HCT)represents an effective therapeutic strategy in AML providing the possibility of cure with potent graft-versus-leukemia reactions,with a demonstrable survival advantage in younger patients with intermediate-or poor-risk cytogenetics.Herein we review the published data regarding the role of allo-HCT in adults with AML.We searched MEDLINE/PubMed and EMBASE/Ovid.In addition,we searched reference lists of relevant articles,conference proceedings and ongoing trial databases.We discuss the role of allo-HCT in AML patients stratified by cytogenetic-and molecular-risk in first complete remission,as well as allo-HCT as an option in relapsed/refractory AML.Besides the conventional sibling and unrelated donor allografts,we review the available data and recent advances for alternative donor sources such as haploidentical grafts and umbilical cord blood.We also discuss conditioning regimens,including reduced intensity conditioning which has broadened the applicability of allo-HCT.Finally we explore recent advances and future possibilities and directions of allo-HCT in AML.Practical therapeutic recommendations have been made where possible based on available data and expert opinion. | Abraham S Kanate Marcelo C Pasquini Parameswaran N Hari Mehdi Hamadani | 2014 | World Journal of Stem Cells2014，6，2： | 6 |
| 2 | Assessment and comparison of recovery after open and minimally invasive esophagecto- my for cancer: an exploratory study in two centers 显示文摘 | Parameswaran R Titcomb D R Blencowe N S | 2013 | Ann Surg2013，20，6： | 1 |
| 3 | Induced pluripotent stem cells generate both retinal ganglion cells and photoreceptors:therapeutic implications in degenerative changes in glaucoma and age-related macular degeneration显示文摘 | Parameswaran S Balasubramanian S Babai N | | 0，，： | 1 |
| 4 | Regulation of glomerular mesangial cell proliferation in culture by adrenomedulin显示文摘 | Parameswaran N Nambi P Brooks DP | 1999 | Eur J Pharmacol1999，372，1： | 1 |
| 5 | Mechanism of adrenomedullin-stimulated hyaluronic acid release in rat mesangial cells显示文摘 | Parameswaran N Spilman WS Pullen M | 1999 | Eur J Pharmacol1999，370，3： | 1 |
| 6 | Induced pluripotent stem cel s generate both retinal ganglion cel s and photoreceptors:therapeutic implications in degenerative changes in glaucoma and age-related macular degeneration显示文摘 | Parameswaran S Balasubramanian S Babai N | | 0，，04： | 1 |
| 7 | On the polylamellate structure of parenchyma wall in Phyllostachys edulls Riv显示文摘 | Parameswaran N Liese W | 1975 | IAWA Buletinl1975，4，： | 1 |
| 8 | Structure of septate fibers in bamboo 显示文摘 | Parameswaran N Liese W | 1977 | Holzforschung1977，31，： | 1 |
| 9 | Chronic oral nico- tine treatment protects against striatal degeneration in MPTP-treated primates 显示文摘 | Quik M Parameswaran N McCallum SE | 2006 | J Neurochem2006，98，6： | 1 |
| 10 | Multiple roles for nico- !ine in Parkinson' s disease 显示文摘 | Luik M Huang LZ Parameswaran N | 2009 | Biochemical Pharmacology2009，78，7： | 1 |
| 11 | Nicotine reduces levodo- pa-induced dyskinesias in lesioned monkeys 显示文摘 | Quik M Cox H Parameswaran N | 2007 | Ann Neurol2007，62，6： | 1 |
| 12 | Involvement of cAMP-dependent protein kinase and pertussis toxin-sensitive G-proteins in CGRP mediated JNK activation in human neuroblastoma cell line显示文摘 | Disa J Parameswaran N Nambi P | | 0，，3： | 1 |
| 13 | Seroprevalence of Toxoplasma gondii in wild kangaroos using an ELISA显示文摘 | Parameswaran N O'handley R M Grigg M E | 2009 | Parasitol Int2009，58，2： | 1 |
| 14 | Induced pluripotent stem cells generate both retinal ganglion cells and photoreceptors:therapeutic implications in degenerative changes in glaucoma and age-related macular degeneration显示文摘 | Parameswaran S Balasubramanian S Babai N | | 0，，： | 1 |
| 15 | Nicotine reduces levodopainduced dyskinesias in leision monkeys显示文摘 | Quik M Cox H Parameswaran N | 2007 | Ann Neurol2007，62，7： | 1 |
| 16 | Ontology mapping for the interoperability problem in net- work management显示文摘 | WONG A K Y RAY P PARAMESWARAN N | 2005 | IEEE Journal on Selected Areas in Communication2005，23，10： | 1 |
| 17 | Partial recovery of stria- tal nicotinic receptors in 1-methyl-4-phenyl-l,2,3,6-tetrahydropyri- dine (MPTP)-lesioned monkeys with chronic oral nicotine 显示文摘 | Bordia T Parameswaran N Fan H | 2006 | J Pharmacol Exp Ther2006，319，1： | 1 |
| 18 | Negative growth effects of ciglitazone on kidney interstitial fibroblasts:role of PPAR-gamma显示文摘 | Parameswaran N Hall CS Bomberger JM | 2003 | Kidney Blood Press Res2003，26，1： | 1 |
| 19 | Arrestin-2 and G protein-coupled receptor kinase 5 interact with NF-kappa B1 p105 and negatively regulate lipopo-lysaccharide stimulated ERK1/2 activation in macrophages显示文摘 | Parameswaran N Pao CS Leonhard KS | 2006 | J Biol Chem2006，281，34： | 1 |
| 20 | Modulation of cadmium -induced oxidative stress in Ceratophyllum demersum by zinc involves a- seorbate- glutathione cycle and glutathione metabolism 显示文摘 | Parameswaran A Majeti N V P | 2005 | Plant Physiology and Biochemistry2005，43，： | 1 |
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