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| 1 | 固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验显示文摘控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。 | Web-ster R Salam A de Silva HA Selak V Stepien S Rajapakse S Amarasekara S Amarasena N Billot L de Silva AP Fernando M Guggilla R Jan S Jayawardena J Maulik PK Mendis S Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom S Tisserra N Senaratne V Wijekoon S Wijeyasingam S Rodgers A Patel A 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 7 |
| 2 | Endoscopic ultrasound-guided fiducial marker placement in pancreatic cancer:A systematic review and meta-analysis显示文摘BACKGROUND Pancreatic cancer(PC)mortality remains high despite advances in therapy.Combination chemoradiotherapy offers modest survival benefit over monotherapy with either.Fiducial markers serve as needed landmarks for imageguided radiotherapy(IGRT).Traditionally,these markers were placed surgically or percutaneously with limitations of each.Endoscopic ultrasound-guided placement overcomes these limitations.AIM To evaluate the safety,efficacy,and feasibility of endoscopic ultrasound(EUS)-guided fiducial placement for PC undergoing IGRT.METHODS Articles were searched in MEDLINE,PubMed,and Ovid journals.Pooling was conducted by fixed and random effects models.Heterogeneity was assessed using Cochran’s Q test based upon inverse variance weights.RESULTS Initial search identified 1024 reference articles for EUS-guided fiducial placement in PC.Of these,261 relevant articles were reviewed.Data was extracted from 11 studies(n=820)meeting inclusion criteria.Pooled proportion of successful placement was 96.27%(95%CI:95.35-97.81)with fiducial migration rates low at 4.33%(95%CI:2.45-6.71).Adverse event rates remained low,with overall pooled proportion of 4.85%(95%CI:3.04-7.03).CONCLUSION EUS-guided placement of fiducial markers for IGRT of PC is safe,feasible,and efficacious.The ability to target deep structures under direct visualization while remaining minimally invasive are added benefits.Moreover,the ability to perform fine needle aspiration or celiac plexus neurolysis add value and increase patient-care efficiency.Whether EUS-guided fiducial placement improves outcomes in IGRT or offers any mortality benefits over traditional placement remains unknown and future studies are needed. | Jaymon B Patel Vakya Revanur David G Forcione Matthew L Bechtold Srinivas R Puli | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，8： | 2 |
| 3 | Efficient photon coupling from a diamond nitrogen vacancy center by integration with silica fiber显示文摘A central goal in quantum information science is to efficiently interface photons with single optical modes for quantum networking and distributed quantum computing.Here,we introduce and experimentally demonstrate a compact and efficient method for the low-loss coupling of a solid-state qubit,the nitrogen vacancy(NV)center in diamond,with a single-mode optical fiber.In this approach,single-mode tapered diamond waveguides containing exactly one high quality NV memory are selected and integrated on tapered silica fibers.Numerical optimization of an adiabatic coupler indicates that near-unity-efficiency photon transfer is possible between the two modes.Experimentally,we find an overall collection efficiency between 16%and 37%and estimate a single photon count rate at saturation above 700 kHz.This integrated system enables robust,alignment-free,and efficient interfacing of single-mode optical fibers with single photon emitters and quantum memories in solids. | Rishi N Patel Tim Schröder Noel Wan Luozhou Li Sara L Mouradian Edward H Chen Dirk R Englund | 2016 | Light(Science & Applications)2016，5，1： | 2 |
| 4 | A micmRNA upregulated in asthma airway T cells promotes TH2 cytokine production显示文摘 | Simpson L J Patel S Bhakta N R | 2014 | Nat Immunol2014，15，12： | 1 |
| 5 | Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121 显示文摘 | Lee L Y Patel S R Hackett N R | 2000 | Ann Thprac Surg2000，69，1： | 1 |
| 6 | Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice显示文摘 | Lacek K Vercauteren K Grzyb K Naddeo M Verhoye L Slowikowski M P Fafi-Kremer S Patel A H Baumert T F Folgori A Leroux-Roels G Cortese R Meuleman P Nicosia A | 2012 | J Hepatol2012，57，1： | 1 |
| 7 | New wine in old bottles: technological diffusion in developed economies显示文摘 | Robertson P L Patel P R | 2007 | Research Policy2007，，36： | 1 |
| 8 | Electronic effects on dislocation velocities in heavily doped silicon显示文摘 | PATEL J R TESTARDI L R FREELAND P E | 1976 | Physical Review B1976，13，8： | 1 |
| 9 | Buckycolumn electrodes: a practical and improved alternative to conventional materials utilised for biological electrochemical monitoring显示文摘 | Fagan-Murphy A Whitly R L D Patel B A | 2013 | Journal of Materials Chemistry B2013，1，35： | 1 |
| 10 | Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy显示文摘 | Hounsom L Corder R Patel J | 2007 | Diabetologia2007，44，4： | 1 |
| 11 | Risks of intravitreous injection: a comprehensive review 显示文摘 | JAGER R D AIELLO L P PATEL S C | 2004 | Retina2004，24，5： | 1 |
| 12 | Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expres- sion in endothelial cell function显示文摘 | Patel N S Li J L Generali D Poulsom R Cranston D W Harris A L | 2005 | Cancer Res2005，65，： | 1 |
| 13 | New wine in old bottles Technological diffusion in developed economies显示文摘 | Robertson P L Patel P R | 2007 | Re-search Policy2007，，36： | 1 |
| 14 | The lncRNA PCAT29 inhibits oncogenic phenotypes in prostate cancer显示文摘 | MALIK R PATEL L PRENSNER J R | 2014 | Mol Cancer Res2014，12，8： | 1 |
| 15 | Covalent antithrombin-heparin complexes显示文摘 | Berry L R Chan A K C | 2007 | Thrombosis Research2007，120，： | 1 |
| 16 | Environmental photooxidation of dibenzothiophenes following the Amoco Cadiz oil spill 显示文摘 | Patel J R Overton E B Laster J L | 1979 | Chemosphere1979，8，： | 1 |
| 17 | The effects of yoga on physical functioning and health related quality of life in older adults:a systematic review and meta-analysis 显示文摘 | Patel N K Newstead A H Ferrer R L | 2012 | The Journal of Alternative and Complementary Medi-cine2012，18，10： | 1 |
| 18 | Hydroxylation of mutilin by streptomyces griseus and cunninghamella echinulata显示文摘 | HANSON R L MATSON J A BRZOZOWSKI D B LAPORTE T L SPRINGER D M PATEL R N | 2002 | Org Process Res Dev2002，6，4： | 1 |
| 19 | Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: A prospective randomized study 显示文摘 | PATEL A N GEFFNER L VINA R F | 2005 | J Thorac Cardiovasc Surg2005，130，： | 1 |
| 20 | Relation of duration of symptoms with response to thrombolytic therapy in pulmonary embolism显示文摘 | DANIELS L B PARKER J A PATEL S R | 1997 | Am J Cardiol1997，80，2： | 1 |
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