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| 1 | 固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验显示文摘控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。 | Web-ster R Salam A de Silva HA Selak V Stepien S Rajapakse S Amarasekara S Amarasena N Billot L de Silva AP Fernando M Guggilla R Jan S Jayawardena J Maulik PK Mendis S Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom S Tisserra N Senaratne V Wijekoon S Wijeyasingam S Rodgers A Patel A 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 7 |
| 2 | White matter hyperintensity progression is associated with incident probable dementia or mild cognitive impairment显示文摘Background White matter hyperintensity(WMH)on brain MRI is associated with developing dementia or mild cognitive impairment(MCI),but WMH progression over time has not been fully investigated as an independent risk factor.Methods We performed a post hoc analysis of the Systolic Blood Pressure Intervention Trial-Memory and Cognition in Decreased Hypertension(SPRINT MIND)trial.The primary outcome was incident probable dementia or MCI(dementia/MCI)before the follow-up MRI at 48 months from enrolment.The primary predictor was WMH progression,defined as the Z score difference between the follow-up and baseline WMH volumes.The secondary predictor was a binary WMH progression threshold(≥1.4 mL vs<1.4 mL).Results Among the 433 included patients,33(7.6%)developed dementia/MCI.There were 156(36.0%)patients who met the WMH progression threshold of≥1.4 mL,in whom the rate of dementia/MCI was 12.8%(20/156)vs 4.7%(13/277)of patients with<1.4 mL WMH progression(p=0.002).In multivariable logistic regression,the Z score of WMH progression was associated with dementia/MCI(OR 1.51,95%CI 1.12 to 2.04,p=0.007)as was the WMH progression threshold of≥1.4 mL(OR 2.89,95%CI 1.23 to 6.81,p=0.015).Conclusions In this post hoc analysis of SPRINT MIND,WMH progression over 48 months was associated with the development of probable dementia or MCI. | Adam de Havenon Kevin N Sheth Sharon D Yeatts Tanya N Turan Shyam Prabhakaran | 2022 | Stroke & Vascular Neurology2022，7，4： | 2 |
| 3 | Noneaterified fatty acids as mediators of glucose intolerance in Indian Asian populations 显示文摘 | Patel JV Vyas A Prabhakaran D | 2005 | Diabetes Care2005，28，： | 1 |
| 4 | Synthesis and in vivo evaluation of a novel 5-HT1A receptor agonist radioligand 2-( 4-( 4-(2-methoxyphenyl) piperazin-1-yl) butyl )-4-methyl-1, 2, 4-triazine-3, 5 ( 2H, 4H)dione in nonhuman primates 显示文摘 | Kumar J S D Prabhakaran J Majo V J | 2007 | Eur J Nucl Med2007，34，7： | 1 |
| 5 | Enhancing the wear resistance of case carburized steel ( En 353 ) by cryogenic treatment显示文摘 | Bensely A Prabhakaran A Mohan Lal D | 2005 | Cryogenics2005，45，12： | 1 |
| 6 | The metabolic syndrome:an emerging risk state for cardiovascular disease显示文摘 | PRABHAKARAN D ANAND SS | 2004 | Vasc Med2004，9，1： | 1 |
| 7 | Incremental value of lef ventricular systolic and diastolic function to determine outcome in patients with acute ST-segment elevation myocardial infarction:the echocardiographic substudy of the OASIS-6 trial显示文摘 | Dokainish H Rajaram M Prabhakaran D | 2014 | Echocardiography2014，31，5： | 1 |
| 8 | Enhancing the wear resistance of case carburized steel (En 353) by cryogenic treatment显示文摘 | Bensely A Prabhakaran A Mohan Lal D Nagarajan G | 2006 | Cryogenics2006，45，： | 1 |
| 9 | Integrating mental health into cardiovascular disease research in India显示文摘 | Narayanan G Prabhakaran D | 2012 | Natl reed J India2012，25，5： | 1 |
| 10 | Impact of new legislation on presumed consent on organ donation on liver transplant in Singapore: a preliminary analysis 显示文摘 | Low H Costa M D Prabhakaran K | 2006 | Transplantation2006，82，9： | 1 |
| 11 | Rationale and design of the coronary artery bypass grafting surgery off or on pump revascularization study: a large international randomized trial in cardiac surgery显示文摘 | Lamy A Deverreaux P J Prabhakaran D | 2012 | Am heart J2012，163，1： | 1 |
| 12 | Does uric acid qualify as an independent risk factor for cardiovascular mortality? 显示文摘 | Jeemon P Prabhakaran D | 2013 | Clin Sci (Lond)2013，124，4： | 1 |
| 13 | The Effects of Attrition and Ball Milling on the Properties of Magnesium Dibo-ride显示文摘 | Dancer C E J Prabhakaran D CrossleyA | | 0，，： | 1 |
| 14 | Premature coronary heart disease risk factors & reducing the CHD burden in India显示文摘 | Prabhakaran D Singh K | | 0，，01： | 1 |
| 15 | Cystic lym- phangioma of the mesentery causing intestinal obstruction显示文摘 | Prabhakaran K Patankar J Z Loh D L | 2007 | Singapore Med J2007，48，10： | 1 |
| 16 | Morphology and etching studies on YBCO and CuO single-crystals显示文摘 | Prabhakaran D Subramanian C Balak umar S | 1999 | Physica C1999，，： | 1 |
| 17 | Effect of 14 weeks of resistance training on lipid profile and body fat percentage in premenopausal women显示文摘 | Prabhakaran B Dowling E A Branch J D | 1999 | Sport Med1999，33，3： | 1 |
| 18 | Elastothermo hydro- dynamic Effects in Elliptical Bearing显示文摘 | Singh D V Sinhasan R Prabhakaran Nair K | 1989 | Tribology International1989，22，1： | 1 |
| 19 | Effects of off-pump and on-pump coronary-artery bypass grafting at 1 year显示文摘 | Lamy A Devereaux P J Prabhakaran D | 2013 | N Engl J Med2013，368，13： | 1 |
| 20 | Development ot a clinical risk score in predicting undiagnosed diabetes in urban Asian Indian adults: a population-based study显示文摘 | Chaturvedi V Reddy KS Prabhakaran D | 2008 | CVD Prey Control2008，3，3： | 1 |
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