|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Outcomes of critically ill cancer patients with Acinetobacter baumannii infection显示文摘AIM: To describe the intensive care unit(ICU) outcomes of critically ill cancer patients with Acinetobacter baumannii(AB) infection.METHODS: This was an observational study that included 23 consecutive cancer patients who acquired AB infections during their stay at ICU of the National Cancer Institute of Mexico(INCan), located in Mexico City. Data collection took place between January 2011, and December 2012. Patients who had AB infections before ICU admission, and infections that occurred during the first 2 d of ICU stay were excluded. Data were obtained by reviewing the electronic health record of each patient. This investigation was approved by the Scientific and Ethics Committees at INCan. Because of its observational nature, informed consent of the patients was not required.RESULTS: Throughout the study period, a total of 494 critically ill patients with cancer were admitted to the ICU of the INCan, 23(4.6%) of whom developed AB infections. Sixteen(60.9%) of these patients had hematologic malignancies. Most frequent reasons for ICU admission were severe sepsis or septic shock(56.2%) and postoperative care(21.7%). The respiratory tract was the most frequent site of AB infection(91.3%). The most common organ dysfunction observed in our group of patients were the respiratory(100%), cardiovascular(100%), hepatic(73.9%) and renal dysfunction(65.2%). The ICU mortality of patients with 3 or less organ system dysfunctions was 11.7%(2/17) compared with 66.6%(4/6) for the group of patients with 4 or more organ system dysfunctions(P = 0.021). Multivariate analysis identified blood lactate levels(BLL) as the only variable independently associated with inICU death(OR = 2.59, 95%CI: 1.04-6.43, P = 0.040). ICU and hospital mortality rates were 26.1% and 43.5%, respectively.CONCLUSION: The mortality rate in critically ill patients with both HM, and AB infections who are admitted to the ICU is high. The variable most associated with increased mortality was a BLL ≥ 2.6 mmol/L in the first day of stay in the ICU. | Silvio A ?amendys-Silva Paulina Correa-García Francisco J García-Guillén María O González-Herrera Américo Pérez-Alonso Julia Texcocano-Becerra Angel Herrera-Gómez Patricia Cornejo-Juárez Abelardo Meneses-García | 2015 | World Journal of Critical Care Medicine2015，4，3： | 3 |
| 2 | Ly49 receptors activate angiogenic mouse DBA+ uterine natural killer cells显示文摘 | Patricia DA Lima Megan M Tu Mir Munir A Rahim Annie R Peng B Anne Croy Andrew P Makrigiannis | 2014 | Cellular & Molecular Immunology2014，11，5： | 3 |
| 3 | Relation of atrophic gastritis with Helicobacter pylori-CagA^+ and interleukin-1 gene polymorphisms显示文摘AIM: To determine the association of Helicobacter pylori (H pylori) CagA+ infection and pro-inflammatory poly-morphisms of the genes interleukin (IL)-1RN and IL-1B with the risk of gastric atrophy and peptic ulcers in a dyspeptic population in Costa Rica, a country with high incidence and mortality of gastric cancer. METHODS: Seven biopsy specimens, a fasting blood sample and a questionnaire concerning nutritional and sociodemographic factors were obtained from 501 con-secutive patients who had undergone endoscopy for dyspeptic symptoms. A histopathological diagnosis was made. Pepsinogen concentrations were analyzed by enzyme linked immunosorbent assay (ELISA). Infection with H pylori CagA+ was determined by serology and polymerase chain reaction (PCR). IL-1B and IL-1RN polymorphisms genotyping was performed by PCR-restriction fragment length polymorphism (PCR-RFLP)and PCR respectively. RESULTS: In this dyspeptic population, 86% were H pylori positive and of these, 67.8% were positive for CagA. Atrophic antral gastritis (AAG) was associated with CagA+ status [odd ratio (OR) = 4.1; P < 0.000] and fruit consumption (OR = 0.3; P < 0.00). Atrophic body gastritis (ABG) was associated with pepsinogen PGI/PGII < 3.4 (OR = 4.9; P < 0.04) and alcohol consumption (OR = 7.3; P < 0.02). Duodenal ulcer was associated with CagA+ (OR = 2.9; P < 0.04) and smoking (OR = 2.4; P < 0.04). PGI < 60 μg/L as well as PGI/PGII < 3.4 were associated with CagA+. CONCLUSION: In a dyspeptic population in Costa Rica, H pylori CagA+ is not associated with ABG, but it is a risk factor for AAG. The pro-inflammatory cytokine poly-morphisms IL-1B + 3945 and IL-1RN are not associated with the atrophic lesions of this dyspeptic population. | Rafaela Sierra Clas Une Vanessa Ramírez Warner Alpízar-Alpízar María I González José A Ramírez Antoine de Mascarel Patricia Cuenca Guillermo Pérez-Pérez Francis Mégraud | 2008 | World Journal of Gastroenterology2008，14，42： | 2 |
| 4 | Uncommon features of pulmonary Langerhans' cell histiocytosis: analysis of 11 cases and a review of the literature显示文摘 | LING Chun-hua JI Cheng Daniel P Raymond Patricia A Bourne XU Hao-dong | 2010 | Chinese Medical Journal2010，，4： | 2 |
| 5 | Silent diabetic nephropathy显示文摘AIM: To examine the risk of renal events in patients with biopsy-proven diabetic nephropathy(DN) and its possible associated factors.METHODS: Clinical and histological data of 60 patients diagnosed with diabetic nephropathy were retrospectively collected. Patients with evidence or suspicion of other nephropathies were excluded from the study. The final event was defined as renal replacement therapy(RRT) initiation or progression of chronic kidney disease(CKD), according to the KDIGO 2012 definition of a decrease in CKD category and a decrease in GFR of 25% or more. RESULTS: A total of 45 patients with a follow-up of at least 3 mo were included. Most of the patients presented type 2 DM, with a median age of 58.3 years old. The time of evolution of DM was 9.6 ± 7.8 years, although in 13 patients, it was less than 5 years. A total of 62% of patients reached the final event in a mean period of 3.4 years(95%CI: 2.1-4.7), with 21 of them requiring dialysis. The factors that were independently associated with renal survival were estimated glomerular filtration rate(e GFR) at the time of biopsy, cardiovascular disease(CVD) history and Hb A1 c less than 7%. Therefore, for each 10 m L/min per 1.73 m2 reduction in e GFR, we obtained a DN progression risk of HR = 2(1.3-3.0)(P = 0.001); patients with CVD were at greater risk for DN progression(HR = 2.8, 1.1-7.1, P = 0.032), and CKD patients with Hb A1 c < 7% demonstrated greater renal risk than patients with Hb A1 c ≥ 7%, with an HR of 2.9(1.0-8.4)(P = 0.054).CONCLUSION: A past history of CVD is a risk factor for DN progression. Levels of Hb A1 c less than 7% could favor an e GFR decrease in these patients. | Katia López-Revuelta Patricia Pea Galdo Ramona Stanescu Leticia Parejo Carmen Guerrero Elia Pérez-Fernández | 2014 | World Journal of Nephrology2014，3，1： | 2 |
| 6 | Variations in microbial community composition through two soil depth profiles显示文摘 | NOAH F JOSHUA P S PATRICIA A H | 2003 | Soil Biol Biochem2003，35，1： | 1 |
| 7 | Variations in microbial communitycomposition through two soil depth profiles显示文摘 | NOAH F JOSHUA P S PATRICIA A H | 2003 | Soil Biology and Biochemistry2003，35，1： | 1 |
| 8 | Nitrate in drinking water and the incidence of gastric,esophageal,and brain cancerin Yorkshire,England显示文摘 | Jennifer H B Roger C P Patricia A M | 1998 | Cancer Causes and Control1998，，9： | 1 |
| 9 | A com- parison of surface water natural organic matter in raw filtered wa- ter samples, XAD, and reverse osmosis isolates 显示文摘 | PATRICIA A M M1VHAEL J P STEPHEN E C | 2002 | Water Re- search2002，36，： | 1 |
| 10 | A comparative study on growth limits of Listeria monocytogenes affected by temperature,pH and aw when grown in suspension or on a solid surface显示文摘 | Konstantions p K Patricia A K John N S et a/ | 2004 | International Journal of Food Microbiology2004，21，4： | 1 |
| 11 | Variations in microbialcommunity composition through two soil depth profiles显示文摘 | Noah F Joshua P S Patricia A H | 2003 | Soil Biology and Biochemistry2003，35，16： | 1 |
| 12 | Risk of Liver Decompensation Among HIV/Hepatitis C Virus–Coinfected Individuals With Advanced Fibrosis: Implications for the Timing of Therapy显示文摘 | Juan Macías Manuel Márquez Francisco Téllez Dolores Merino Patricia Jiménez-Aguilar Luis F. López-Cortés Enrique Ortega Miguel A. von Wichmann Antonio Rivero María Mancebo Jesús Santos Montserrat Pérez-Pérez Ignacio Suárez-Lozano Alberto Romero-Palacios A | 2013 | Clinical Infectious Diseases2013，，10： | 1 |
| 13 | 查看详情显示文摘 | María L G P Patricia P B Roberto R G José L M V Antonia G F | | 0，，27： | 1 |
| 14 | International entrepreneurship and geographic location: an empirical examination of new venture internationalization 显示文摘 | STEPHANIE A FERNHABER BRETT ANITRA GILBERT PATRICIA P McDOUGALL | 2008 | Journal of International Business Studies2008，39，： | 1 |
| 15 | The emergence of entrepre- neurship policy 显示文摘 | Brett A G David B A Patricia P M | 2004 | Small Business Economics2004，22，34： | 1 |
| 16 | Ethanol specifically decreases peroxisome proliferator-activated receptor δ in B12 oligodendrocyte-like cells显示文摘 | Leisewitz A V Jung J E Patricia P A | 2003 | J Neurochem2003，85，1： | 1 |
| 17 | Preservation needs of children' s literature in academic libraries 显示文摘 | Morris P Patricia A | 2010 | Portal -Libraries and the Academy2010，10，1： | 1 |
| 18 | Physiological and Biochemical Effects of the Myeotoxin Patulin on Chang Liver Cell Cultures显示文摘 | Warren I S Nancy E S Patricia A P | 1975 | In Vitro Cell DevPl1975，11，2： | 1 |
| 19 | Variations in microbial community composition through two soil depth profiles 显示文摘 | Noah F Joshua P S Patricia A H | 2003 | Soil Biology and Biochemistry2003，，35： | 1 |
| 20 | Influence of microstructure on rock elastic properties显示文摘 | PATRICIA A B BERRYMAN J G BONNER B P | | 0，，23： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员