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| 1 | How to assess intestinal viability during surgery: A review of techniques显示文摘Objective and quantitative intraoperative methods of bowel viability assessment are essential in gastrointestinal surgery. Exact determination of the borderline of the viable bowel with the help of an objective test could result in a decrease of postoperative ischemic complications. An accurate, reproducible and cost effective method is desirable in every operating theater dealing with abdominal operations. Numerous techniques assessing various parameters of intestinal viability are described by the studies. However, there is no consensus about their clinical use. To evaluate the available methods, a systematic search of the English literature was performed. Virtues and drawbacks of the techniques and possibilities of clinical application are reviewed. Valuable parameters related to postoperative intestinal anastomotic or stoma complications are analyzed. Important issues in the measurement and interpretation of bowel viability are discussed. To date, only a few methods are applicable in surgical practice.Further studies are needed to determine the limiting values of intestinal tissue oxygenation and flow indicative of ischemic complications and to standardize the methods. | Linas Urbanaviius Piet Pattyn Dirk Van de Putte Donatas Venskutonis | 2011 | World Journal of Gastrointestinal Surgery2011，3，5： | 4 |
| 2 | Near-infrared fluorescence guided esophageal reconstructive surgery: A systematic review显示文摘BACKGROUND After an esophagectomy, the stomach is most commonly used to restore continuity of the upper gastrointestinal tract. These esophago-gastric anastomoses are prone to serious complications such as leakage associated with high morbidity and mortality. Graft perfusion is considered to be an important predictor for anastomotic integrity. Based on the current literature we believe Indocyanine green fluorescence angiography(ICGA) is an easy assessment tool for gastric tube(GT) perfusion, and it might predict anastomotic leakage(AL).AIM To evaluate feasibility and effectiveness of ICGA in GT perfusion assessment and as a predictor of AL.METHODS This study was designed according to the PRISMA guidelines and registered in the PROSPERO database. PubMed and EMBASE were independently searched by 2 reviewers for studies presenting data on intraoperative ICGA GT perfusion assessment during esophago-gastric reconstruction after esophagectomy.Relevant outcomes such as feasibility, complications, intraoperative surgical changes based on ICGA findings, quantification attempts, anatomical data and the impact of ICGA on postoperative anastomotic complications, were collected by 2 independent researchers. The quality of the included articles was assessed based on the Methodological Index for Non-Randomized Studies. The 19 included studies presented data on 1192 esophagectomy patients, in 758 patients ICGA was used perioperative to guide esophageal reconstruction.RESULTS The 19 included studies for qualitative analyses all described ICGA as a safe and easy method to evaluate gastric graft perfusion. AL occurred in 13.8% of the entire cohort, 10% in the ICG guided group and 20.6% in the control group(P <0.001). When poorly perfused cases are excluded from the analyses, the difference in AL was even larger(AL well-perfused group 6.3% vs control group 20.5%, P <0.001). The AL rate in the group with an altered surgical plan based on the ICG image was 6.5%, similar to the well perfused group(6.3%) and significantly less than the poorly perfused group(47.8%)(P < 0.001), suggesting that the technique is able to identify and alter a potential bad outcome.CONCLUSION ICGA is a safe, feasible and promising method for perfusion assessment. The lower AL rate in the well perfused group suggest that a good fluorescent signal predicts a good outcome. | Elke Van Daele Yves Van Nieuwenhove Wim Ceelen Christian Vanhove Bart P Braeckman Anne Hoorens Jurgen Van Limmen Oswald Varin Dirk Van de Putte Wouter Willaert Piet Pattyn | 2019 | World Journal of Gastrointestinal Oncology2019，11，3： | 3 |
| 3 | Lymphatic spread, nodal count and the extent of lymphadenectomy in cancer of the colon显示文摘 | Wouter Willaert Marc Mareel Dirk Van De Putte Yves Van Nieuwenhove Piet Pattyn Wim Ceelen | 2014 | Cancer Treatment Reviews2014，，3： | 2 |
| 4 | Outcome following laparoscopic and open total mesorectal excision for rectal cancer显示文摘 | F. Penninckx A. Kartheuser J. Van de Stadt P. Pattyn B. Mansvelt C. Bertrand E. Van Eycken D. Jegou S. Fieuws | 2013 | Br J Surg2013，，10： | 2 |
| 5 | Detection of Chlamydia trachomatis and Nelsseria gonorrhoeae by enzyme immunoassay, culture,and three nucleic acid amplification tests显示文摘 | Van Dyck E Ieven M Pattyn S | 2001 | Clin Microbiol2001，39，： | 1 |
| 6 | Accurate normalization of real- time quantitative RT - PCR data by geometric averaging of multiple internal control genes 显示文摘 | VANDESOMPELE J DE PRETER K PATTYN F | 2002 | Genome Biol2002，3，7： | 1 |
| 7 | Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internalcontrol genes显示文摘 | VANDESOMPELE J De PRETER K PATTYN F etal | 2002 | Genome Biology2002，3，7： | 1 |
| 8 | Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes显示文摘 | VANDESOMPELE J De PRETER K PATTYN F | 2002 | Genome Biol2002，3，7： | 1 |
| 9 | New insights intothe surgical anatomy of the rectum: a review 显示文摘 | Willaert W Pattyn P Van De Putte D | 2011 | Acta Chir Belg2011，111，5： | 1 |
| 10 | Accurate normali-zation of real-time quantitative RT-PCR data by geometric avera-ging of multiple internal control genes显示文摘 | Vandesompele J De Preter K Pattyn F | 2002 | Genome Biol2002，18，3： | 1 |
| 11 | Diffenrent levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification 显示文摘 | Vallstedt A Muhr J Pattyn A | 2001 | Neuron2001，31，： | 1 |
| 12 | Isolation of Enterococcus avium from bile and blood in a patient with acute cholecystitis 显示文摘 | Verhaegen J Pattyn P Hinnekens P | 1997 | The Journal of Infection1997，35，1： | 1 |
| 13 | RTPrimerDB: the realtime PCR primer and probe database显示文摘 | Pattyn F Speleman F De Paepe A | 2003 | Nucleic Acids Res2003，31，1： | 1 |
| 14 | Early complications after revision total hip arthroplasty with cemented dual-mobility socket and reinforcement ring显示文摘 | Pattyn C Audenaert E | 2012 | Acta Orthop Belg2012，78，3： | 1 |
| 15 | Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes显示文摘 | VANDESOMPELE J DE PRETER K PATTYN F | 2002 | Genome Biology2002，3，7： | 1 |
| 16 | Cell cycle effect of gemcitabine and its role in the radiosensitizing mechanism in vitro显示文摘 | Pauwels B Korst AE Pattyn GG | 2003 | Int J Radiat Oncol Biol Phys2003，57，4： | 1 |
| 17 | Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes 显示文摘 | Vandesompele J De Preter K Pattyn F | 2002 | Genome Biol2002，3，7： | 1 |
| 18 | 2002, Accurate normalization of Real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes 显示文摘 | Vandesompele J De Preter K Pattyn F | 2002 | Genome Biology2002，3，7： | 1 |
| 19 | HyperISGylation of Old World monkey ISG15 in human cells显示文摘 | Pattyn E Verhee A Uyttendaele I | 2008 | PLoS ONE2008，3，6： | 1 |
| 20 | Accurate normalization of real-time q-uantitative RT-PCR data by geometric aberaging of multiple internal control genes显示文摘 | Vandesompels J De Preter K Pattyn F | 2002 | Genome Biol2002，3，7： | 1 |
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