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| 1 | Pediatric functional constipation treatment with Bifi dobacterium-containing yogurt:A crossover,double-blind,controlled trial显示文摘AIM: To evaluate the treatment of pediatric functional chronic intestinal constipation (FCIC) with a probiotic goat yogurt. METHODS: A crossover double-blind formula-controlled trial was carried out on 59 students (age range: 5-15 years) of a public school in Belo Horizonte, MG, Brazil, presenting a FCIC diagnostic, according to Roma Ⅲ criteria. The students were randomized in two groups to receive a goat yogurt supplemented with 109 colony forming unit/mL Bifidobacterium longum (B.longum) (probiotic) daily or only the yogurt for a period of 5 wk (formula). Afterwards, the groups were intercrossed for another 5 wk. Defecation frequency, stool consistency and abdominal and defecation pain were assessed.RESULTS: Both treatment groups demonstrated improvement in defecation frequency compared to baseline. However, the group treated with probiotic showed most signif icant improvement in the f irst phase of the study. An inversion was observed after crossing over, resulting in a reduction in stool frequency when this group was treated by formula. Probiotic and formula improved stool consistency in the f irst phase of treatment, but the improvement obtained with probiotic was significantly higher (P = 0.03). In the second phase of treatment, the group initially treated with probiotic showed worseningstool consistency when using formula. However, the difference was not signif icant. A signif icant improvement in abdominal pain and defecation pain was observed with both probiotic and formula in the first phase of treatment, but again the improvement was more signif icant for the group treated with B. longum during phase I (P < 0.05). When all data of the crossover study were analyzed, significant differences were observed between probiotic yogurt and yogurt only for defecation frequency (P = 0.012), defecation pain (P = 0.046) and abdominal pain (P = 0.015). | Paula VP Guerra Luiza N Lima Tassia C Souza Vanessa Mazochi Francisco J Penna Andreia M Silva Jacques R Nicoli Elizabet V Guimares | 2011 | World Journal of Gastroenterology2011，17，34： | 25 |
| 2 | The meaning of specializa- tion for the nurse in the field of stomas显示文摘 | De Paula M A Santos V L | 2003 | Rev Lat Am Enfermagem2003，11，4： | 1 |
| 3 | In vitro assessment of Metarhizium anisopliae isolates to control the cattle tick Boophilus microplus 显示文摘 | Ana Paula G F habajara da S V J Aoi M | 2000 | Veterinary Parasitology2000，91，： | 1 |
| 4 | Fish off flavor analysis by hcadspace and off line purge-and-trap followed by HRGC MS 显示文摘 | Santos G V Da Cunha Veloso M C De Paula Pereira PA | 2001 | American Lab-oratory2001，33，24： | 1 |
| 5 | Purification and substrate specificity of an angiotensin coverting elas- tase-2 from the rat mesenteric arterial bed perfusate显示文摘 | PAULA C A SOUSA M V SALGADO M C | 1998 | Biochimaica et Biophysica Acta1998，1338，1： | 1 |
| 6 | Reactive dyes remotion by porous TiO2-chitosan materials显示文摘 | CAROLINA E Z PAULA V M CARINA L | 2008 | Journal of Hazardous materials2008，152，： | 1 |
| 7 | Two circadian timing circuits in Neurospora crassa cells share components and regulate distinct rhythmic processes显示文摘 | DE PAULA R M LEWIS Z A GREENE A V | 2006 | J Biol Rhythms2006，21，3： | 1 |
| 8 | Heat stress impairs performance and induces intestinal inflammation in broiler chickens infected with Salmonella enteritidis显示文摘 | Quinteiro Filho W M Gomes A V Pinheiro M L Ribeiro A Ferraz-de Paula V AstoIfi Ferreira C S Ferreira A J Palermo- Neto J | 2012 | Avian Pathology2012，41，5： | 1 |
| 9 | Hepatitis E virus in swine and effluent samples from slaughterhouses in Bra- zil显示文摘 | Dos Santos D R de Paula V S de Oliveira J M | 2011 | Veterinary Microbiology2011，149，12： | 1 |
| 10 | Knowledge and prevalence of viral hepatitis among beauti- cians显示文摘 | Villar L M de Paula V S de Almeida A J | 2014 | J Med Virol2014，86，9： | 1 |
| 11 | Fish off-flavor analysis by headspace and off-line purgeand-trap followed by HRGC-MS显示文摘 | Santos G V Da Cunha Veloso M C De Paula Pereira P A | 2001 | American Laboratory2001，33，24： | 1 |
| 12 | Angiotensin-(1-7) potentiates the hypotensive effect of bradykinin in conscious rats显示文摘 | PAULA R D LIMA C V KHOSLA M C | 1995 | Hypertension1995，26，62： | 1 |
| 13 | Efeito da calagem,potassio e nitrogenio na producao e qualidade do fruto do abacaxizeiro显示文摘 | Paula M B Carvalho V D Nogueira F D | 1991 | Pesquisa Agropecu6ria Brasileira1991，26，7： | 1 |
| 14 | Modification of Poly (Lactides) by Blending: Mechanical and Hydrolytic Behavior显示文摘 | HiIjanen-Vainio M Paula V Jukka S | 1996 | Macromol Chem Phys1996，197，： | 1 |
| 15 | Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting显示文摘 | DE PAULA D M V L B R I | 2007 | RNA2007，13，： | 1 |
| 16 | Evalu- ation of methods used to concentrate and detect hepatitis Avirus in water samples显示文摘 | Villar L M de Paula V S Diniz - Mendes L | 2006 | Journal of virological methods2006，137，2： | 1 |
| 17 | Fish off flavor analysis by headspace and off-line purge and trap followed by HRGC-MS显示文摘 | SANTOS G V DA CUNHA VELOSO M C DE PAULA PEREIRA P A | 2001 | American Iaboratory2001，33，24： | 1 |
| 18 | Simultaneous determination of benzoic and sorbic acids in quince jam by HPLC 显示文摘 | Isabel M P L V O Ferreira Eullia Mendes Paula Brito | 2000 | Food Research International2000，33，： | 1 |
| 19 | Fish off-flavor analysis by headspace and off-line purge-and-trap followed by HRGC-MC显示文摘 | Santos G V Da Cunha Veloso M C De Paula Pereira P A | 2001 | American Laboratory2001，33，24： | 1 |
| 20 | In vitro assess-ment of Metarhizium anisopliaeisolates to control the cattle tickBoophilus microplus 显示文摘 | Ana Paula G F Itabajara da S V J Aoi M | 2000 | Veterinary Parasitology2000，94，11： | 1 |
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