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112篇 您的检索式:作者名="Pearl L"
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1Diagnostic accuracy of endoscopic ultrasound in pancreatic neuroendocrine tumors: A systematic review and meta analysis显示文摘AIM: To detect pancreatic neuroendocrine tumors (PNETs) has been varied. This study is undertaken to evaluate the accuracy of endoscopic ultrasound (EUS) in detecting PNETs.METHODS: Only EUS studies confirmed by surgery or appropriate follow-up were selected. Articles were searched in Medline, Ovid journals, Medline nonindexed citations, and Cochrane Central Register of Controlled Trials and Database of Systematic Reviews. Pooling was conducted by both fixed and random effects model). RESULTS: Initial search identified 2610 reference articles, of these 140 relevant articles were selected and reviewed. Data was extracted from 13 studies (n = 456) which met the inclusion criteria. Pooled sensitivity of EUS in detecting a PNETs was 87.2% (95%CI: 82.2-91.2). EUS had a pooled specificity of 98.0% (95%CI: 94.3-99.6). The positive likelihood ratio of EUS was 11.1 (95%CI: 5.34-22.8) and negative likelihood ratio was 0.17 (95%CI: 0.13-0.24). The diagnostic odds ratio, the odds of having anatomic PNETs in positive as compared to negative EUS studies was 94.7 (95%CI: 37.9-236.1). Begg-Mazumdar bias indicator for publication bias gave a Kendall's tau value of 0.31 (P = 0.16), indication no publication bias. The P for χ2 heterogeneity for all the pooled accuracy estimates was > 0.10. CONCLUSION: EUS has excellent sensitivity and specificity to detect PNETs. EUS should be strongly considered for evaluation of PNETs.Srinivas R Puli Nikhil Kalva Matthew L Bechtold Smitha R Pamulaparthy Micheal D Cashman Norman C Estes Richard H Pearl Fritz-Henry Volmar Sonu Dillon Michael F Shekleton David Forcione 2013World Journal of Gastroenterology2013,19,23:14
2Structure and mechanism of the Hsp90 molecular chaperone machinery显示文摘Pearl L H Prodromou C 2006Annu Rev Biochem2006,75,:1
3On the rate of growth of the popula- tion of the United States since 1790 and its mathematical representation 显示文摘PEARL R REED L J 1920Proceedings of the National Academy of Sciences1920,,6:1
4Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair 显示文摘Spagnolo L Rivera-Calzada A Pearl L H 2006Mol Cell2006,22,4:1
5Estimating species phylogenies using coalescence times among sequences显示文摘Liu L Yu LL Pearl DK Edwards SV 0,,:1
6Structure and mechanism of the HsPg0 molecular chaperone machinery 显示文摘PEARL L H PRODROMOU C 2006Annu Rev Biochem2006,75,:1
7Maximum tree:a consistent estimator of the species tree显示文摘Liu L Yu LL Pearl DK 0,,:1
8Recursive PCR:a novel technique for total gene synthesis显示文摘Prodromou C Pearl L H 1992Protein Engineering1992,5,:1
9The HSP90 molecular chaperone: an open and shut case for treatment显示文摘PEARL L H PRODROMOU C WORKMAN P 2008Bio- chem J2008,410,3:1
10Structural model for the retroviral protease显示文摘Pearl L H Taylor W R A 1987Nature1987,329,:1
11Structure and in vivo function of Hsp90 显示文摘Pearl L H Prodromou C 2000Curr Opin Struct Biol2000,10,:1
12Proximal humeral anatomy in shoulder arthroplasty: implication for prothetic design anti surgical technique 显示文摘Pearl M L 2005J Shoulder Elbow Surg2005,14,1:1
13On the rate of growth of the population of the United States since 1790 and its mathematical representation 显示文摘PEARL R REED L J 1920Proc Nat Acad Sci1920,6,:1
14The Hsp90 molecular chaperone:an open and shut case for treatment显示文摘Pearl L H Prodromou C Workman P 2008Biochem J2008,410,3:1
15显示文摘Pearl I A Beyer D L 1950TAPPI1950,33,:1
16On the rate of growth of the popu- lation of the United States since 1790 and its mathemati- cal representation 显示文摘PEARL R REED L J 1920Proc Natl Acad Sci1920,6,:1
17A second front against AIDS显示文摘Blundell T Pearl L 1989Nature1989,337,60376039:1
18Structure and mechanism of the Hsp90 molecular chaperone machinery显示文摘PEARL L H PRODROMOU C 2006Annual Review of Biochemistry2006,75,:1
19Endovascular treatment of aneu- rysmal subaraehnoid hemorrhage显示文摘Pearl M Gregg L Gailloud P 2010Neurosurg Clin N Am2010,21,:1
20Structure and functional relationships of Hsp90显示文摘PRODROMOU C PEARL L H 2003Current Cancer Drug Targets2003,3,5:1
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