维普期刊资源整合服务平台（V6.5）

276篇 您的检索式：作者名="Pearson D A"

选中清除导出查看参考文献查看引证文献引用追踪共14页首页上一页第1页下一页末页 /14 跳转

	题名	作者	年代	出处	被引量
1	Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.	Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels	2010	World Journal of Gastroenterology2010，16，6：	11
2	Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience显示文摘	Phil A Hart Mark D Topazian Thomas E Witzig Jonathan E Clain Ferga C Gleeson Robin R Klebig Michael J Levy Randall K Pearson Bret T Petersen Thomas C Smyrk Aravind Sugumar Naoki Takahashi Santhi S Vege Suresh T Chari	2013	Gut2013，，11：	2
3	Treatment of relapsing autoimmune pancreatitis with immunomodulators and rituximab: the Mayo Clinic experience显示文摘	Phil A Hart Mark D Topazian Thomas E Witzig Jonathan E Clain Ferga C Gleeson Robin R Klebig Michael J Levy Randall K Pearson Bret T Petersen Thomas C Smyrk Aravind Sugumar Naoki Takahashi Santhi S Vege Suresh T Chari	2013	Gut2013，，11：	2
4	Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients 显示文摘	Lamont J M McManamy C S Pearson A D	2004	Clin Cancer Res2004，10，：	1
5	Metabolic relations to temperatures in the copepods Diaptomus dorsalis and Mesocyclopes edax from North-Central Texas显示文摘	Smith G A Fitzpatrick L C Pearson W D		0，，：	1
6	Molecular signatures in biopsy specimens of lung cancer显示文摘	Borczuk A C Shah L Pearson G D	2004	Am J Respir Crit Care Med2004，170，2：	1
7	The MUC2 gene product: a human intestinal mucin 显示文摘	Allen A Hutton D A Pearson J R	1998	Int J Biochem Cell Biol1998，30，7：	1
8	Concentration-dependent effects of 9-cisretinoic acid on neuroblastoma differentiation and proliferation in vitro显示文摘	Lovat P E Lsmis S P Pearson A D	1994	Neurosci Lett1994，182，1：	1
9	Is the short rate drift actually nonlinear?显示文摘	Chapman D A Pearson N D	2000	Journal of Finance2000，55，1：	1
10	Assessment of chemotherapy-associated nephrotoxicity in children with cance显示文摘	SKINNE R PEARSON A D COULTHARD M G	1991	Cancer chemotherapy pharmacology1991，28，2：	1
11	Fluorination in nematic systems显示文摘	Balkwill P Bishop D Pearson A	1985	Mol Cryst Liq Cryst1985，123，：	1
12	Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain显示文摘	Pearson MA Reczek D Bretscher A	2000	Cell2000，101，3：	1
13	Under-standing the dynamics of new venture top managementteams cohesion,conflict,and new venture performance显示文摘	ENSLEY M D PEARSON A W AMASON A C	2002	Journal of Business Venturing2002，17，：	1
14	Quantitative analysis of trace elements in geolog-ical materials by laser ablation ICP-MS: Instru- mental operating conditions and calibration values of NIST glassesp显示文摘	Norman M D Pearson N J Sharma A	1996	Geostandards newsletter1996，20，：	1
15	Occurrence of velogenic viscerotropic Newcastle disease in pet and exotic birds in 1991显示文摘	Panigraphy B Senne D A Pearson J E	1993	Avian Dis1993，37，：	1
16	Characterization of Newcastledisease virus (Paramyxovirus 1)isolated from pigeons 显示文摘	Pearson J E Senne D A Alexander D J	1987	Avian Dis1987，31，：	1
17	Lipid oxidation in meat and meat products: a review显示文摘	LOVE J D PEARSON A M	1971	Journal of the American Oil Chemists'' Society1971，48，10：	1
18	Anterior chamber implantation after vitreous loss 显示文摘	PEARSON P A OWEN D G MALISZEWSKI M	1989	Br J Ophthalmol1989，73，7：	1
19	On the existence and role of free radicals in methanol conversion to hydrocarbons over HZSM-5 I: inhibition by NO显示文摘	Chang C D Hellring S D Pearson J A	1989	J Catal1989，115，：	1
20	Assessing the impact of chemotherapy-induced nausea and vomiting on patients’ daily lives: a modified version of the Functional Living Index-Emesis (FLIE) with 5-day recall显示文摘	Martin A R Pearson J D Cai B	2003	Support Care Cancer2003，11，：	1

返回顶部每页显示：

共14页首页上一页第1页下一页末页 /14 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示