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| 1 | Pediatric functional constipation treatment with Bifi dobacterium-containing yogurt:A crossover,double-blind,controlled trial显示文摘AIM: To evaluate the treatment of pediatric functional chronic intestinal constipation (FCIC) with a probiotic goat yogurt. METHODS: A crossover double-blind formula-controlled trial was carried out on 59 students (age range: 5-15 years) of a public school in Belo Horizonte, MG, Brazil, presenting a FCIC diagnostic, according to Roma Ⅲ criteria. The students were randomized in two groups to receive a goat yogurt supplemented with 109 colony forming unit/mL Bifidobacterium longum (B.longum) (probiotic) daily or only the yogurt for a period of 5 wk (formula). Afterwards, the groups were intercrossed for another 5 wk. Defecation frequency, stool consistency and abdominal and defecation pain were assessed.RESULTS: Both treatment groups demonstrated improvement in defecation frequency compared to baseline. However, the group treated with probiotic showed most signif icant improvement in the f irst phase of the study. An inversion was observed after crossing over, resulting in a reduction in stool frequency when this group was treated by formula. Probiotic and formula improved stool consistency in the f irst phase of treatment, but the improvement obtained with probiotic was significantly higher (P = 0.03). In the second phase of treatment, the group initially treated with probiotic showed worseningstool consistency when using formula. However, the difference was not signif icant. A signif icant improvement in abdominal pain and defecation pain was observed with both probiotic and formula in the first phase of treatment, but again the improvement was more signif icant for the group treated with B. longum during phase I (P < 0.05). When all data of the crossover study were analyzed, significant differences were observed between probiotic yogurt and yogurt only for defecation frequency (P = 0.012), defecation pain (P = 0.046) and abdominal pain (P = 0.015). | Paula VP Guerra Luiza N Lima Tassia C Souza Vanessa Mazochi Francisco J Penna Andreia M Silva Jacques R Nicoli Elizabet V Guimares | 2011 | World Journal of Gastroenterology2011,17,34: | 25 |
| 2 | Transanal total mesorectal excision: Myths and reality显示文摘Transanal total mesorectal excision(TaTME) is a new and promising approach for the treatment of rectal cancer. Whilst the experience is still limited, there are growing evidences that this approach might overcome the limits of standard low anterior resection. TaTME might help to decrease the conversion rate especially in difficult patients, and to improve the pathological results, while preserving the urogenital function. Evaluation of data from large registries and randomized studies should help to draw firmer conclusions. Beyond these technical considerations, the next challenge seems to be clearly the safe introduction of this approach, motivating the development of dedicated courses. | Nicolas C Buchs Marta Penna Alexander L Bloemendaal Roel Hompes | 2016 | World Journal of Clinical Oncology2016,7,5: | 5 |
| 3 | Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B:new perspectives for immune therapy显示文摘 | Boni C Penna A Ogg GS | 2001 | Hepatology2001,33,4: | 1 |
| 4 | Spontaneous and prostatic steroid binding protein peptide-induced autoimmune prostatitis in the nonobese diabetic mouse显示文摘 | Penna G Amuchastegui S Cossetti C | | 0,,: | 1 |
| 5 | The paradigm of postconditioning to protect the heart 显示文摘 | PENNA C MANCARDI D RAIMONDO S | 2008 | J Cell Mol Med2008,12,2: | 1 |
| 6 | Optimization of Nisin Production by Lactococcus lactis 显示文摘 | Penna T C Moraes D A | 2002 | Appl Biochem Biotechnol2002,98,100: | 1 |
| 7 | Effect of endothe- lins on the cardiovascular system 显示文摘 | Penna C Rastaldo A Mancardi D | 2012 | J Cardiovasc Med2012,7,9: | 1 |
| 8 | Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B显示文摘 | Boni C Bertoletti A Penna A | | 0,,: | 1 |
| 9 | Effects of a protocol of ischemic postconditioning and/or captopril in hearts of normotensive and hypertensive rats显示文摘 | Penna C Tullio F Moro F | 2010 | Basic Res Cardiol2010,105,2: | 1 |
| 10 | Post-ischemic early acidosis in cardiac postconditioning modifies the activity of antioxidant enzymes,reduces nitration,and favors protein S-nitrosylation显示文摘 | Penna C Perrelli MG Tullio F | | 0,,: | 1 |
| 11 | Postconditioning induces an anti-apoptotic effect and preserves mitochondrial integrity in isolated rat hearts显示文摘 | Penna C Perrelli MG Raimondo S | 2009 | Biochim Biophys Acta2009,1787,7: | 1 |
| 12 | Evaluation of recombinant green fluorescent protein,under various culture conditions and purification with Hi Trap hydrophobic interaction chromatography resins显示文摘 | PENNA T C V ISHII M JUNIOR A P | | 0,,1: | 1 |
| 13 | Complete response of coloreetal liver metastases after chemotherapy: Does it mean cure? 显示文摘 | Benoist S Brouquet A Penna C | 2006 | J Clin Oncol2006,24,24: | 1 |
| 14 | Postconditioning induced eardioproteetion requires signaling through a redox-sensitive mechanism, mitochondrial ATP- sensitive K^+ channel and protein kinase C activation 显示文摘 | PENNA C RASTALDO R MANCARDI D | 2006 | Basic Res Cardiol2006,101,2: | 1 |
| 15 | The platelet activating factor triggers preconditioning-like eardioprotective effect via mitochondrial K-ATP channels and redox-sensible signaling 显示文摘 | Penna C Mognetti B Tullio F | 2008 | J Physiol Pharmacol2008,59,1: | 1 |
| 16 | MicroRNA -214 contributes to melanoma tumour progression through suppression of TFAP2C显示文摘 | Penna E Orso F Cimino D Tenag|ia E Lembo A Quaglino E Poliseno L Haimovic A Osella-Abate S De Pitta C Pinatel E Stadler M B Provero P Bemengo M G Osman I Taverna D | 2011 | EMBO Journal2011,30,10: | 1 |
| 17 | 'Mitochondrial pathways, permeability transition pore, and redox signaling in cardioprotec- tion: therapeutic implications显示文摘 | Penna C Perrelli MG Pagliaro P | 2013 | Antioxid Redox Signal2013,18,5: | 1 |
| 18 | Colorectal metastasis (liver and lung) 显示文摘 | PENNA C NORDLINGER B | 2002 | Surg Clin North Am2002,82,5: | 1 |
| 19 | Effect of endothelins on the cardiovascular system 显示文摘 | Penna C Rastaldo R Mancardi D | 2006 | J Cardiovasc Med (Hagerstown)2006,7,9: | 1 |
| 20 | Influence of pre- operative chemotherapy on the risk of major hepatectomy for colorectal liver metastases 显示文摘 | Karoui M Penna C Amin-Hashem M | 2006 | Ann Surg2006,243,1: | 1 |