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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，13： | 17 |
| 2 | Full Robotic Gastrectomy with Extended (D2) Lymphadenectomy for Gastric Cancer: Surgical Technique and Preliminary Results显示文摘 | Annibale D’Annibale Vito Pende Graziano Pernazza Igor Monsellato Paolo Mazzocchi Giorgio Lucandri Emilio Morpurgo Tania Contardo Gianna Sovernigo | 2011 | Journal of Surgical Research2011，，2： | 2 |
| 3 | Robotic Right Colon Resection: Evaluation of First 50 Consecutive Cases for Malignant Disease显示文摘 | Annibale D’Annibale MD Graziano Pernazza MD Emilio Morpurgo MD Igor Monsellato MD Vito Pende MD Giorgio Lucandri MD Barbara Termini MD Camillo Orsini MD Gianna Sovernigo MD | 2010 | Annals of Surgical Oncology2010，，11： | 1 |
| 4 | Regulation ofmatrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for meta- static disease显示文摘 | Johnson J L Pillai S Pernazza D | 2012 | Cancer Res2012，72，： | 1 |
| 5 | Full robotic gastrectomy with extended (D2) lymphadenectomy for gastric cancer: surgical tec h nique and preliminary results 显示文摘 | D'Annibale A Pende V Pernazza G | 2011 | J Surg Res2011，166，2： | 1 |
| 6 | Robotic right colon resection: evaluation of first 50 consecutive cases for malignant disease显示文摘 | D'Annibale A Pernazza G Morpurgo E | 2010 | Ann Surg Oncol2010，17，： | 1 |
| 7 | Robotic right colon reseetion evaluation of first 50 consecutive cases for malignant disease显示文摘 | D'Annibale A Pernazza G Morpurgo E | 2010 | Ann Surg Oncol2010，17，11： | 1 |
| 8 | Robotic right co- lon resection: evaluation of first 50 consecutive cases for malig- nant disease 显示文摘 | D'Annibale A Pernazza G Morpurgo E | 2010 | Ann Surg Oncol2010，17，11： | 1 |
| 9 | Total mesorectal excision: a comparison of oncological and functional outcomes between robotic and laparoscopic surgery for rectal cancer显示文摘 | Annibale D’Annibale Graziano Pernazza Igor Monsellato Vito Pende Giorgio Lucandri Paolo Mazzocchi Giovanni Alfano | 2013 | Surgical Endoscopy2013，，6： | 1 |
| 10 | Total mesoreetal excision: a comparison of oncological and functional outcomes between robotic and laparoscopic surgery for rectal cancer 显示文摘 | D'ANN1BALE A PERNAZZA G MONSELLATO I | 2013 | Surg Endosc2013，27，6： | 1 |
| 11 | Robotic right colon resection: evaluation of first 50 consecutive cases for malignant disease显示文摘 | D'Annibale A Pernazza G Morpurgo E | 2010 | Ann Surg Oncol2010，17，： | 1 |
| 12 | Regulation of matrix metalloproteinase genes by E2F transcription factors:Rb-Raf-1 interaction as a novel target for metastatic disease显示文摘 | Johnson JL Pillai S Pernazza D | | 0，，： | 1 |
| 13 | Full robotic gastrectomy with extended(D2)lymphadenectomy for gastric cancer:surgical technique and preliminary results显示文摘 | D’Annibale A Pende V Pernazza G | 2011 | J Surg Res2011，166，2： | 1 |
| 14 | Full robotic gastrec- tomy with extended (D2) lymphadenectomy for gastric cancer: surgical technique and preliminary results显示文摘 | D' Annibale A Pende V Pernazza G | 2011 | J Surg Res2011，166，2： | 1 |
| 15 | Full robotic gastrectomy with extended (D2) lymphadenectomy for gastric cancer: surgical technique and preliminary results 显示文摘 | D' Annibale A Pende V Pernazza G | 2011 | J Surg Res2011，166，2： | 1 |
| 16 | Robotic Right Colon Resection: Evaluation of First 50 Consecutive Cases for Malignant Disease显示文摘 | Annibale D’Annibale Graziano Pernazza Emilio Morpurgo Igor Monsellato Vito Pende Giorgio Lucandri Barbara Termini Camillo Orsini Gianna Sovernigo | 2010 | Annals of Surgical Oncology2010，，11： | 1 |
| 17 | Robotic right colon resection : evaluation of first 50 consecutive cases for malignant dis-ease显示文摘 | D'Annibale A Pernazza G Morpurgo E | 2010 | Ann Surg Oncol2010，17，11： | 1 |
| 18 | Full robotic gastrectomy with extended (D2) lymphadenectomy for gastric cancer: surgical technique and preliminary results显示文摘 | D'Annibale A Pende V Pernazza G | 2011 | J Surg Res2011，166，2： | 1 |
| 19 | Robotic Right Colon Resection: Evaluation of First 50 Consecutive Cases for Malignant Disease显示文摘 | Annibale D’Annibale Graziano Pernazza Emilio Morpurgo Igor Monsellato Vito Pende Giorgio Lucandri Barbara Termini Camillo Orsini Gianna Sovernigo | 2012 | Indian Journal of Surgical Oncology2012，，4： | 1 |
| 20 | Full robotic gastrecto- my with extended (D2) lymphadenectomy for gastric cancer: sur- gical technique and preliminary results 显示文摘 | D'Annibale A Pende V Pernazza G | 2011 | J Surg Res2011，166，2： | 1 |
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