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| 1 | High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6. | Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders | 2016 | Horticulture Research2016,3,1: | 6 |
| 2 | Diagnostic accuracy of tests for Helicobacter pylori in an Alaska Native population显示文摘AIM:To evaluate the accuracy of two non-invasivetests in a population of Alaska Native persons. Highrates of Helico bacter pylori(H. pylori) infection,H. pylori treatment failure,and gastric cancer in this population necessitate documentation of infection status atmultiple time points over a patient's life.METHODS:In 280 patients undergoing endoscopy,H. pylori was diagnosed by culture,histology,rapidurease test,13C urea breath test(UBT) ,and immuno-globulin G antibodies to H. pylori in serum. The performances of 13C-UBT and antibody test were compared to a gold standard defined by a positive H. pylori testby culture or,in case of a negative culture result,bypositive histology and a positive rapid urease test.RESULTS:The sensitivity and specificity of the 13C-UBT were 93% and 88%,respectively,relative to thegold standard. The antibody test had an equivalents ensitivity of 93% with a reduced specificity of 68%.The false positive results for the antibody test were as-sociated with previous treatment for an H. pylori infection [relative risk(RR) = 2.8]. High levels of antibodiesto H. pylori were associated with chronic gastritis and male gender,while high scores in the 13C-UBT testwere associated with older age and with the H. pyloribacteria load on histological examination(RR = 4.4) .CONCLUSION:The 13C-UBT out performed the anti-body test for H. pylori and could be used when a non-invasive test is clinically necessary to document treatment out come or when monitoring for reinfection. | Dana L Bruden Michael G Bruce Karen M Miernyk Julie Morris Debby Hurlburt Thomas W Hennessy Helen Peters Frank Sacco Alan J Parkinson Brian J McMahon | 2011 | World Journal of Gastroenterology2011,17,42: | 3 |
| 3 | Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials显示文摘 | Naveed Sattar David Preiss Heather M Murray Paul Welsh Brendan M Buckley Anton JM de Craen Sreenivasa Rao Kondapally Seshasai John J McMurray Dilys J Freeman J Wouter Jukema Peter W Macfarlane Chris J Packard David J Stott Rudi G Westendorp James Shepherd | 2010 | The Lancet2010,,9716: | 2 |
| 4 | Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials显示文摘 | Naveed Sattar David Preiss Heather M Murray Paul Welsh Brendan M Buckley Anton JM de Craen Sreenivasa Rao Kondapally Seshasai John J McMurray Dilys J Freeman J Wouter Jukema Peter W Macfarlane Chris J Packard David J Stott Rudi G Westendorp James Shepherd | 2010 | The Lancet2010,,9716: | 2 |
| 5 | Interaction between cisplatin and gemcitabine in vitro and in vivo 显示文摘 | Peters G J Bergman A M Ruiz van Haperen V W | 1995 | Semin Oncol1995,22,411: | 1 |
| 6 | Capsaicin-evoked brain activation and central sensitization in anaesthetised rats:A functional magnetic resonance imaging study显示文摘 | Ricardo J M G Peter G M Malcolm J W P | 2006 | Pain2006,126,13: | 1 |
| 7 | The WindSat Spaceborne Polarimetric Microwave Radiometer: Sensor Description and Early Orbit Performance显示文摘 | Peter W G Karen M St Genmain | 2004 | IEEE Trans On Geoscience and Remote Sensing2004,42,11: | 1 |
| 8 | Analytical Algorithms for Lake Water TSM Estimation for Retrospective Analyses of TM and SPOT Sensor Data显示文摘 | Dekker A G Vos R J Peters S W M | 2002 | International Journal of Remote Sensing2002,23,1: | 1 |
| 9 | Differemiad constitutive equations for polymer mehs: The extended Pom--Ponl model显示文摘 | Verbeeten W M H Peters G W M Baaljens F | 2001 | Journal of Rheology2001,45,4: | 1 |
| 10 | Analytical algorithms for lake water TSM estimation for retrospective analyses of TM and SPOT sensor data显示文摘 | DEKKER A G VOS R J PETERS S W M | 2002 | International Journal of Remote Sensing2002,23,1: | 1 |
| 11 | Paul alivisatos semiconductor nanocrystals as fluorescent biological labels显示文摘 | Marcel Bruchez Jr Mario M Peter G Shimon W | 1998 | Science1998,281,: | 1 |
| 12 | The Influence of Cooling Rate on the Specific Volume ofIsotactic Poly(propylene) at Elevated Pressures 显示文摘 | Vander Beek M H E Peters G W M Meijer H E H | 2005 | Mac-romolecular Materials and Engineering2005,290,: | 1 |
| 13 | Five-dimensional optical re-cording mediated by surface plasmons in gold nanorods显示文摘 | PETER Z JAMES W M C MIN G | 2009 | Na-ture2009,459,7245: | 1 |
| 14 | Model uncertainty in claims reserving within Tweedie's com- pound Poisson models显示文摘 | Peters G W Shevchenko P V Wtithrich M V | 2009 | Astin Bulletin2009,39,01: | 1 |
| 15 | Stability analysis of injection molding flows显示文摘 | BOGAERDS A C B HULSEN M A PETERS G W M | 2004 | Journal of Rheology2004,48,4: | 1 |
| 16 | Von Hippel-Lindau disease:genetic,clinical,and imaging feature显示文摘 | Peter L C Gladys M G Meclellan M W | 1995 | Radiology1995,194,: | 1 |
| 17 | A Three-dimensional Computa- tional Analysis of Fluid-structure Interaction in the Aortic Valve 显示文摘 | J De Hart G W M Peter | 2003 | Journal of Biomechanics2003,,36: | 1 |
| 18 | The use of the Thematic Mapper for the analysis of eutrophic lakes: a case study in the Netherlands显示文摘 | Dekker A G Peters S W M | 1993 | International Journal of Remote Sensing1993,14,5: | 1 |
| 19 | The use of the thematic mapper for the analysis of eutrophic lakes: a case study in the Nether lands 显示文摘 | Dekker A G Peters S W M | 1993 | Int J Remote Sensing1993,14,: | 1 |
| 20 | Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B显示文摘 | Peters M G Hann H W Martin P | 2004 | Gastroenterology2004,162,1: | 1 |