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24篇 您的检索式:作者名="Philips CL"
    题名 作者 年代 出处 被引量
1Data-intensive applications, challenges, techniques and technologies: A survey on Big Data显示文摘CL Philip Chen Chun-Yang Zhang 2014Information Sciences2014,275,10:1
2Phase ⅡI study comparing gemcitabine plus cetuximab bersus gemcitabine in patients with advanced pancreatic ademocarcinoma: southwest oneology group-directed intergroup trial 显示文摘PHILIP PA BENEDETTI J CORLESS CL 2010J Clin Oncol2010,28,22:1
3Endoscopic submucosal dissection vs laparoscopic colorectal resection for early colorectal epithelial neoplasia显示文摘AIM: To compare the short term outcome of endoscopic submucosal dissection(ESD) with that of laparoscopic colorectal resection(LC) for the treatment of early colorectal epithelial neoplasms that are not amenable to conventional endoscopic removal. METHODS: This was a retrospective cohort study. The clinical data of all consecutive patients who underwent ESD for endoscopically assessed benign lesions that were larger than 2 cm in diameter from 2009 to 2013 were collected. These patients were compared with a cohort of controls who underwent LC from 2005 to 2013. Lesions that were proven to be malignant by initial endoscopic biopsies were excluded. Mid and lower rectal lesions were not included because total mesorectal excision, which bears a more complicated postoperative course, is not indicated for lesions without histological proof of malignancy. Both ESD and LC were performed by the same surgical unit with a standardized technique. The patients were managed according to a standard protocol, and they were closely monitored for complications after the procedures. All hospital records were reviewed, and the following data were compared between the ESD and LC groups: patient demographics, size and location of the lesions, procedure time, shortterm clinical outcomes and pathology results. RESULTS: From 2005 to 2013, 65 patients who underwent ESD and 55 patients who underwent LC were included in this study. The two groups were similar in terms of sex(P = 0.41) and American Society of Anesthesiologist class(P = 0.58), although patients in the ESD group were slightly older(68.6 ± 9.4 vs 64.6 ± 9.9, P = 0.03). ESD could be accomplished with a shorter procedure time(113 ± 66 min vs 153 ± 43 min, P < 0.01) for lesions of comparable size(3.0 ± 1.2 cm vs 3.4 ± 1.4 cm, P = 0.22) and location(colon/rectum:59/6 vs colon/rectum: 52/3, P = 0.43). ESD appeared to be associated with a lower short-term complication rate, but the difference did not reach statistical significance(10.8% vs 23.6%, P = 0.06). In the LC arm, a total of 22 complications occurred in 13 patients. A total of 7 complications occurred in the ESD arm, including 5 perforations and 2 episodes of bleeding. All perforations were observed during the procedure and were successfully managed by endoscopic clipping without emergency surgical intervention. Patients in the ESD arm had a faster recovery than patients in the LC arm, which included shorter time to resume normal diet(2 d vs 4 d, P = 0.01) and a shorter hospital stay(3 d vs 6 d, P < 0.01). CONCLUSION: ESD showed better short-term clinical outcomes in this study. Further prospective randomized studies will be required to evaluate the efficacy and superiority of colorectal ESD over LC.Sophie SF Hon Simon SM Ng Tiffany CL Wong Philip WY Chiu Tony WC Mak WW Leung Janet FY Lee 2015World Journal of Gastrointestinal Endoscopy2015,7,17:1
4Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adeno- carcinoma: Southwest Oncology Group-directed inter- group trial S0205显示文摘Philip PA Benedetti J Corless CL 2010J Clin Oncol2010,28,22:1
5Phase m study comparing gemcitabine plus cetuximab versus gemeitabine in patients with advanced paiicreatic ad Southwest oncology group-directed intergroup trim S0205 显示文摘Philip PA Benedetti J Corless CL 2010J Clin 0ncol2010,28,22:1
6Phase III studycomparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: South- west Oncology Group-directed intergroup trial $0205 显示文摘Philip PA Benedetti J Corless CL 2010J Clin Oncol2010,28,22:1
7The role of calcitonin and ct-calcitonin gene-related peptide in bone formation显示文摘Antje H Johannes K Philip CL 2008Arch Biochem Biophy2008,473,2:1
8PhaseⅢstudy comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma:Southwest Oncology Groupdirected intergroup trial S0205显示文摘Philip PA Benedetti J Corless CL 2010J Clin Oncol2010,28,22:1
9Phase Ⅲ study comparing gemcitabine plus cetuximah versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group- directed intergroup trial S0205显示文摘Philip PA Benedetti J Corless CL 2010J Clin Oncol2010,28,22:1
10Differential localization of myosin-Ⅱ isozymes in human cultured cells and blood cells显示文摘Maupin P Philips CL Adelstein RS 0,,:1
11Genetic analysis in the Collaborative Cross breeding population 显示文摘Philip VM Sokoloff G Ackert-Bicknell CL 2011Genome Res2011,21,8:1
12Phase Ⅲ sduty comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma:Southwest Oncology Group-directed intergroup trial S0205显示文摘Philip PA Benedetti J Codess CL 2010J Clin Oncol2010,28,22:1
13The effect of short -term with- drawal from continuous positive airway pressure therapy on sympathetic activity and markers of vascular inflammation in subjects with obstructive sleep apnea 显示文摘Philips CL Yang Q Williams A 2007J Sleep Res2007,16,2:1
14Phase III study comparing gemeitabine plus cetuximab versus gemeitabine in patients with ad- vanced pancreatic adenocarcinoma: Southwest Oncology Group - di- rected intergroup trial S0205 显示文摘Philip PA Benedetti J Corless CL 2010J Clin Oneol2010,28,22:1
15Phase IIa randomized, placebo-controlled study of antimicrobialphotodynamic therapy in bacterially colonized, chronic legulcers and diabetic foot ulcers: a new approach to antimicrobialtherapy显示文摘Morley S Griffiths J Philips G Moseley H O'Grady C MellishK Lankester CL Faris B Young RJ Brown SB Rhodes LE 2013Br J Dermatol2013,168,3:1
16Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205 显示文摘Philip PA Benedetti J Corless CL 2010J Clin Oncol2010,28,22:1
17Phase III study compa- ring gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205 显示文摘Philip PA Benedetti J Corless CL 2010J Clin Oncol2010,28,22:1
18Phase III study of gemcitabine plus cetuximab versus gemcitabine in patients with locally advanced or metastatic pancreatic adenocarcinoma: Southwest Oncology Group-directed S0205 study 显示文摘PHILIP PA BENEDETTI J CORLESS CL 2010J Clin Oncol2010,28,22:1
19Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: southwest oncology group-directed intergroup trial S0205 显示文摘Philip PA Benedetti J Corless CL 2010J Clin Oncol2010,28,22:1
20Efficient algorithm for the reconstruction of 3D objects from orthographic projections显示文摘Qing-Wen Yan CL Philip Chen Zesheng Tang 1994Computer Aided Design1994,26,9:1
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