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| 1 | Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting. | Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov | 2014 | World Journal of Gastroenterology2014，20，45： | 9 |
| 2 | Aperture averaging of optical scintillations:power fluctuations and the temporal spectrum 显示文摘 | ANDREWS L C PHILLIPS R L HOPEN C Y | 2000 | Wave Random Media2000，10，1： | 2 |
| 3 | Adsorption of Salmonella enteritidis by cetylpyridinium exchanged montmorillonite clays显示文摘 | HERRERA P BURGHARDY R C PHILLIPS T D | 2000 | Microbiology2000，74，： | 2 |
| 4 | Plant regeneratiaon from tissue culture of maize显示文摘 | GREEN C E PHILLIPS R L | 1995 | Crop Sci1995，15，： | 1 |
| 5 | The molecular hiology of the flavin-containing nlonooxygenases of man显示文摘 | Phillips I R Dolphin C T Clair P | 1995 | Chem Biol Interact1995，96，1： | 1 |
| 6 | Determination of organic acids in Vaccinium berry standard reference materials显示文摘 | Phillips M M Case R J Rimmer C A Sander L C Sharpless K E Wise S A Yen J H | 2010 | Analytical and Bioanalytical Chemistry2010，398，1： | 1 |
| 7 | Synthesis, characterization, and hydrodesulfurization properties of silica- supported molybdenum phosphide catalysts 显示文摘 | Phillips D C Sawhill S J Self R | 2002 | Journal of Catalysis2002，207，2： | 1 |
| 8 | Adaptation of HIV-1to human leukocyte antigen class I显示文摘 | Kawashima Y Pfafferott K Frater J Matthews P Payne R Addo M Gatanaga H Fujiwara M Hachiya A Koizumi H Kuse N Oka S Duda A Prendergast A Crawford H Leslie A Brumme Z Brumme C Allen T Brander C Kaslow R Tang J Hunter E Allen S Mulenga J Branch S Roach T John M Mallal S Ogwu A Shapiro R Prado J G Fidler S Weber J Pybus O G Klenerman P Ndung'u T Phillips R Heckerman D Harrigan P R Walker B D Takiguchi M Goulder P | 2009 | Nature2009，458，7238： | 1 |
| 9 | Measurement o{ sleep in critically ill patients显示文摘 | Richards K C O'Sullivan P S Phillips R L | 2001 | J Nuts Meas2001，8，2： | 1 |
| 10 | Prediction of deposition of calcium sulfate under down-hole conditions显示文摘 | Phillips R C | 1970 | JPT1970，22，7： | 1 |
| 11 | Influence of the attachment of acidophilic bacteria during the oxidation of mineral sulfides显示文摘 | Phillips C V Blake Ⅱ R C | 2000 | Minerals Engineering2000，13，4： | 1 |
| 12 | Nonsteroidal anti- inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm : review of clinical trials and clinical practice 显示文摘 | Moore R A Derry S Phillips C J | 2006 | BMC Musculoskelet Disord2006，20，7： | 1 |
| 13 | Crust-mantle decoupling by flexure of continental lithosphere显示文摘 | Brown C D Phillips R J | 2000 | Jour Geophys Res2000，105，13： | 1 |
| 14 | Laminated steel eddy-current loss versus frequency computedusing finite elements显示文摘 | BRAUER J R CENDES Z J BEIHOFF B C PHILLIPS K P | 2000 | IEEE Transactions on IndustryApplications2000，36，4： | 1 |
| 15 | Strehl ratio and scintillation theory for uplink Gaussian-beam waves: beam wander effects显示文摘 | L C Andrews R L Phillips R J Sasiela | 2006 | Opt Eng2006，45，07： | 1 |
| 16 | Radon mitigation in domestic properties and its health implications--a comparison between during-construction and post-construction radon reduction显示文摘 | Groves-Kirkby C J Denman A R Phillips P S | 2006 | Environ Int2006，32，4： | 1 |
| 17 | Lipase-catalyzed stereoselective esterification of DL-menthol in organic solvents using acid anhydrides as acylating agents 显示文摘 | WU W H AKOH C C PHILLIPS R S | 1996 | Enzyme Microb Technol1996，18，7： | 1 |
| 18 | Friends or strangers? Firm-specific uncertainty, market uncertainty, and network partner selection 显示文摘 | Beckman C M Haunschild P R Phillips D J | 2004 | Organization Science2004，15，3： | 1 |
| 19 | LX-17 comer turning显示文摘 | Souers P C Andreski H G Cook C FⅢ Garza R Pastrone R Phillips D Roeske F Vitello P Molitoris J D | 2004 | Propellants Explosives and Pyrotechnics2004，29，1： | 1 |
| 20 | Theory of optical scintillation显示文摘 | Andrews L C Phillips R L Hopen C Y | 1999 | J Opt Soc Am A1999，16，6： | 1 |
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