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| 1 | Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting. | Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov | 2014 | World Journal of Gastroenterology2014，20，45： | 9 |
| 2 | No association between phosphatase and tensin homolog genetic polymorphisms and colon cancer显示文摘AIM: To investigate the association between single nucleotide polymorphisms (SNPs) in the phosphatase and tensin homolog (PTEN) tumor suppressor gene and risk of colon cancer. METHODS: We utilized a population-based casecontrol study of incident colon cancer individuals (n= 421) and controls (n = 483) aged ≥ 30 years to conduct a comprehensive tagSNP association analysis of the PTEN gene. RESULTS: None of the PTEN SNPs were statistically significantly associated with colon cancer when controlled for age, gender, and race, or when additionally adjusted for other known risk factors (P > 0.05). Haplotype analyses similarly showed no association between the PTEN gene and colon cancer. CONCLUSION: Our study does not support PTEN as a colon cancer susceptibility gene. | Lynette S Phillips Cheryl L Thompson Alona Merkulova Sarah J Plummer Thomas C Tucker Graham Case Li Li | 2009 | World Journal of Gastroenterology2009，15，30： | 2 |
| 3 | Correlation of travel time on roads versus straight-line distance显示文摘 | Phillips C S Luft H S | 1995 | Medicare Research and Review1995，52，4： | 1 |
| 4 | Determination of organic acids in Vaccinium berry standard reference materials显示文摘 | Phillips M M Case R J Rimmer C A Sander L C Sharpless K E Wise S A Yen J H | 2010 | Analytical and Bioanalytical Chemistry2010，398，1： | 1 |
| 5 | Synthesis, characterization, and hydrodesulfurization properties of silica- supported molybdenum phosphide catalysts 显示文摘 | Phillips D C Sawhill S J Self R | 2002 | Journal of Catalysis2002，207，2： | 1 |
| 6 | Adaptation of HIV-1to human leukocyte antigen class I显示文摘 | Kawashima Y Pfafferott K Frater J Matthews P Payne R Addo M Gatanaga H Fujiwara M Hachiya A Koizumi H Kuse N Oka S Duda A Prendergast A Crawford H Leslie A Brumme Z Brumme C Allen T Brander C Kaslow R Tang J Hunter E Allen S Mulenga J Branch S Roach T John M Mallal S Ogwu A Shapiro R Prado J G Fidler S Weber J Pybus O G Klenerman P Ndung'u T Phillips R Heckerman D Harrigan P R Walker B D Takiguchi M Goulder P | 2009 | Nature2009，458，7238： | 1 |
| 7 | Measurement o{ sleep in critically ill patients显示文摘 | Richards K C O'Sullivan P S Phillips R L | 2001 | J Nuts Meas2001，8，2： | 1 |
| 8 | Nonsteroidal anti- inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm : review of clinical trials and clinical practice 显示文摘 | Moore R A Derry S Phillips C J | 2006 | BMC Musculoskelet Disord2006，20，7： | 1 |
| 9 | Elevated levels of lipoprotein (a) in association with cerebrovascular saccular aneurysmal disease 显示文摘 | Bolger C Phillips J Gilligan S | 1995 | Neurosurgey1995，37，： | 1 |
| 10 | Improved bounds on relaxations of a parallel machine scheduling problem显示文摘 | PHILLIPS C A SCHULZ A S SHMOYS D B | 1998 | Journal of Combinatorial Optimization1998，1，4： | 1 |
| 11 | Compar- ison of the quality of protection on elicited by toxoid and peptide liposomal vaccine formulations against riein as as- sessed by markers of inflammation 显示文摘 | GRIFFITHS G D PHILLIPS G J BAILEY S C | 1999 | Vaccine1999，17，： | 1 |
| 12 | Radon mitigation in domestic properties and its health implications--a comparison between during-construction and post-construction radon reduction显示文摘 | Groves-Kirkby C J Denman A R Phillips P S | 2006 | Environ Int2006，32，4： | 1 |
| 13 | Lipase-catalyzed stereoselective esterification of DL-menthol in organic solvents using acid anhydrides as acylating agents 显示文摘 | WU W H AKOH C C PHILLIPS R S | 1996 | Enzyme Microb Technol1996，18，7： | 1 |
| 14 | Porcine oxymyoglobin and lipid oxidation in vitro显示文摘 | LEE S PHILLIPS A L LIEBLER D C | 2003 | Meat Science2003，63，： | 1 |
| 15 | Measure-ment of sleep in critically ill patients显示文摘 | Richards K C O'Sullivan P S Phillips R L | 2000 | J Nurs Meas2000，8，2： | 1 |
| 16 | Thiophene hydrodesulfurization over supported nickel phosphide catalysts 显示文摘 | Sawhill S J Phillips D C Bussell M E | 2003 | Journal of Catalysis2003，215，： | 1 |
| 17 | GDNF: A potent survival factor for motoneurons present in peripheral nerve and muscle显示文摘 | Henderson C E Phillips H S Pollock R A | 1994 | Science1994，266，： | 1 |
| 18 | ENSO and pacific decadal variability in the community climate system model version 4显示文摘 | Deser C Phillips A S Tomas R A | 2012 | Journal of Climate2012，25，8： | 1 |
| 19 | Mag- netic levitation in the analysis of foods and water 显示文摘 | MIRICE K A PHILLIPS S T MACE C R | 2010 | Journal of Agricultural and Food Chemis- try2010，58，11： | 1 |
| 20 | Hepatocyte growth factor (HGF) and the satellite cell response following muscle lengthening contractions in humans 显示文摘 | O' Reilly C McKay B Phillips S | 2008 | Muscle Nerve2008，38，5： | 1 |
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