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| 1 | High prevalence of viable Mycobacterium avium subspecies paratuberculosis in Crohn's disease显示文摘AIM:To examine the detection rate of viable Mycobacterium avium subspecies paratuberculosis(MAP) in patients with inflammatory bowel disease [Crohn's disease(CD) and ulcerative colitis(UC)].METHODS:Thirty patients with CD(15 with at least one NOD2/CARD15 mutation),29 with UC,and 10 with no inflammatory bowel disease(IBD).were tested for MAP by polymerase chain reaction(specific IS900 fragment) and blood culture.RESULTS:MAP DNA was detected in all original blood samples and 8-wk blood cultures(CD,UC and non-IBD).Positive MAP DNA status was confirmed by dot blot assays.All 69 cultures were negative by acid-fast Ziehl-Neelsen staining.Viable MAP,in spheroplast form,was isolated from the 18-mo blood cultures of all 30 CD patients,one UC patient,and none of the non-IBD controls.No association was found between positive MAP cultures and use of immunosuppressive drugs or CDassociated single nucleotide polymorphisms.CONCLUSION:MAP is widely present in our area and MAP DNA can be recovered from the blood of CD,UC and non-IBD patients.However,MAP spheroplasts were only found in CD patients. | Juan L Mendoza Amparo San-Pedro Esther Culebras Raquel Cíes Carlos Taxonera Raquel Lana Elena Urcelay Fernando de la Torre Juan J Picazo Manuel Díaz-Rubio | 2010 | World Journal of Gastroenterology2010，16，36： | 5 |
| 2 | Effects of bromocryptine administration during the follicular phase of the oestrus cycles on prolactin and gonadotrophin secretion and follicular dynamics in Merino monovular ewes 显示文摘 | Picazo R A Bulnes G Brunet G | 2000 | Journal of Reproduction and Fertility2000，120，： | 1 |
| 3 | Laparoscopic appendectomy during pregnancy: between personal experiences and scientific evidence显示文摘 | Moreno Sanz C Pascual-Pedreno A Picazo Yeste JS | 2007 | J Am Coll Surg2007，205，1： | 1 |
| 4 | Assessing farming eco - efficiency: A Data EnvelopmentAnalysis 显示文摘 | Picazo - Tadeo A J Gomez - Limon J A Reig - MartinezE | 2011 | Journal of Environmental Management2011，，92： | 1 |
| 5 | Cellular localization and changes in expression of prolactin receptor isoforms in sheep ovary throughout the estrous cycle显示文摘 | Picazo R A Garcia Ruiz J P Santiago Moreno J | 2004 | Reproduction2004，128，5： | 1 |
| 6 | Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry显示文摘 | Lahoz A Donato M T Picazo L | 2007 | Toxicol In Vitro2007，21，7： | 1 |
| 7 | Polypropylene-clay nanocomposites: effect of compatibilizing agents on clay dispersion显示文摘 | Garcia-Lopez D Picazo O Merino JC | 2003 | Europe Polymer2003，39，5： | 1 |
| 8 | Differ-ent expression of alpha and beta mitochondrial estrogen receptors inthe aging rat brain:interaction with respiratory complex V显示文摘 | Alvarez-Delgado C Mendoza-Rodríguez CA Picazo O | 2010 | ExpGerontol2010，45，： | 1 |
| 9 | Comparative activity of carbapenem testing: the COMPACT study显示文摘 | NORDMANN P PICAZO JJ MUTTERS R et ol | 2011 | J Antimicrob Chemother2011，66，5： | 1 |
| 10 | Assessing eeo - efficiency with directional distance functions 显示文摘 | PICAZO - TADEO A J BELTRoN - ESTEVE M GoMEZ - LIMoN J A | 2012 | European Journal of Operational Research2012，220，3： | 1 |
| 11 | Neuroprotective and neurotoxic effects of estrogens显示文摘 | Picazo O Azcoitia I Garcia-Segura LM | 2003 | Brain Res2003，990，12： | 1 |
| 12 | Influence of cadmium and nickel on growth, net photosynthesis and carbohydrate distribution in rice plants 显示文摘 | Moya J L Ros R Picazo I | 1993 | Photos Res1993，36，： | 1 |
| 13 | Influence of cadmium and nickel on growth, net photosynthesis and carbohydrate distribution in rice plants显示文摘 | J. L. Moya R. Ros I. Picazo | 1993 | Photosynthesis Research1993，，2： | 1 |
| 14 | Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry 显示文摘 | LAHOZ A DONATO M T PICAZO L | 2007 | Toxicol In Vitro2007，21，7： | 1 |
| 15 | Microdetermination of indomethacin in whole blood using HPLC with electrochemical deteclion显示文摘 | PICAZO Y F | 1998 | Rev Mex Cienc Farm1998，29，1： | 1 |
| 16 | Polypropylene clay nanocomposites: Effect of compatibilizing agents on clay dispersion 显示文摘 | PICAZO O MERINO J C PASTOR J M | 2003 | EurPolymJ2003，39，6： | 1 |
| 17 | Identification of Acinetobacter species:is Bruker biotyper MALDI-TOF mass spectrometry a good alternative to molecular techniques显示文摘 | Alvarez-Buylla A Culebras E Picazo JJ | | 0，，： | 1 |
| 18 | Influence of cadmium and nickel on growth, net photosynthesis and carbohydrate distribution in rice plants显示文摘 | J. L. Moya R. Ros I. Picazo | 1993 | Photosynthesis Research1993，，2： | 1 |
| 19 | Assessing farming eco - efficiency: a data envelopment analysis approach 显示文摘 | Picazo - Tadeo A J Reig - Marttnez E Gomez - Limon J A | 2011 | Journal of Environmental Management2011，92，： | 1 |
| 20 | Influence of cadmium and nickel on growth, net photosynthesis and carbohydrate distribution in rice plants 显示文摘 | MOYA J L ROS R PICAZO I | 1993 | Photosynthesis Research1993，36，： | 1 |
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