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| 1 | Perfusion characterization of liver metastases from endocrine tumors:Computed tomography perfusion显示文摘AIM:To assess prospectively parameters of computed tomography perfusion(CT p) for evaluation of vascularity of liver metastases from neuroendocrine tumors.METHODS:This study was approved by the hospital's institutional review board.All 18 patients provided informed consent.There were 30 liver metastases from neuroendocrine tumors.Patients were divided into three groups depending on the appearance of the liver metastases at the arterial phase of morphological CT(hyperdense,hypodense and necrotic).Sequential acquisition of the liver was performed before and for 2 min after intravenous injection of 0.5 mg/kg contrast medium,at 4 mL/s.Data were analyzed using deconvolution analysis to calculate blood flow(BF),blood volume(BV),mean transit time(MTT),hepatic arterial perfusion index(HAPI) and a bi-compartmental analysis was performed to obtain vascular permeability-surface area product(PS).Post-treatment analysis was performed by a radiologist and regions of interest were plotted on the metastases,normal liver,aorta and portal vein.RESULTS:At the arterial phase of the morphological CT scan,the aspects of liver metastases were hyperdense(n=21),hypodense(n=7),and necrotic(n=2).In cases of necrotic metastases,none of the CT p parameters were changed.Compared to normal liver,a significant difference in all CT p parameters was found in cases of hyperdense metastases,and only for HAPI and MTT in cases of hypodense metastases.No significant difference was found for MTT and HAPI between hypo-and hyperdense metastases.A significant decrease of PS,BV and BF was demonstrated in cases of patients with hypodense lesions PS(23±11.6 mL/100 g per minute) compared to patients with hyperdense lesions;PS(13.5±10.4 mL/100 g per minute),BF(93.7±75.4 vs 196.0±115.6mL/100 g per minute) and BV(9.7±5.9 vs 24.5 10.9 mL/100 g).CONCLUSION:CT p provides additional information compared to the morphological appearance of liver metastases. | Aurélie Guyennon Marius Mihaila John Palma Catherine Lombard-Bohas Jean-Alain Chayvialle Frank Pilleul | 2010 | World Journal of Radiology2010，2，11： | 2 |
| 2 | Magnetic resonance imaging follow-up of liver growth of neuroendocrine tumors in an experimental mouse model显示文摘 | Baboi L Pilleul F Milot L | | 0，，： | 1 |
| 3 | Possible small-bowel neoplasms:contrast-enhanced and water-enhanced multidetector CT enteroclysis显示文摘 | Pilleul F Penigaud M Milot M | 2006 | Radiology2006，241，3： | 1 |
| 4 | Possible smallbowel neoplasms:contrast-enhanced and water-enhanced muhidetector CT enteroclysis显示文摘 | Penigaud M Milot L | 2006 | Radiology2006，241，3： | 1 |
| 5 | Diagnosis of splanchnic artery aneurysms and Pseudoaneurysms, with special reference to contrast en- hanced 3D magnetic resonance angiography: areview 显示文摘 | Pilleul F Beuf O | 2004 | Aeta Radiol2004，45，： | 1 |
| 6 | Diagnosis of splanchnic artery aneurysms and pseudoaneurysms,with special reference to contrast enhanced 3D magnetic resonance angiography:a review显示文摘 | Pilleul F Beuf O | | 0，，07： | 1 |
| 7 | Possible small-bowel neoplasms:contrast-enhanced and water-enhanced multidetector CT enteroclysis显示文摘 | PILLEUL F PENIGAUD M MILOT L | 2006 | Radiology2006，241，3： | 1 |
| 8 | Portal Venous Gas Detected on Computed Tomography in Emergency Situations: Surgery Is Still Necessary显示文摘 | Olivier Monneuse MD PhD Frank Pilleul MD PhD Xavier Barth MD Laurent Gruner MD Bernard Allaouchiche MD PhD Pierre-Jean Valette MD E. Tissot MD | 2007 | World Journal of Surgery2007，，5： | 1 |
| 9 | Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults显示文摘 | Saurin JC Pilleul F | 2004 | Gastroenterol Clin Biol2004，28，89： | 1 |
| 10 | Diagnosis of Splanchnic Artery Aneurysms and Peseudoaneurysms, with Special Reference to Contrast Enhanced 3D Magnetic Resonance Angiography: a Review显示文摘 | Pilleul F Beuf O | 2004 | Acta Radio- logica2004，45，7： | 1 |
| 11 | Possible small- bowel neoplasms: contrastenhanced and water -enhanced multidetector CT enteroclysis 显示文摘 | PILLEUL F PENIGAUD M MILOTL etal | 2006 | Radiology2006，241，3： | 1 |
| 12 | Prospective Randomized Study of Doxorubicin-Eluting-Bead Embolization in the Treatment of Hepatocellular Carcinoma: Results of the PRECISION V Study显示文摘 | Johannes Lammer Katarina Malagari Thomas Vogl Frank Pilleul Alban Denys Anthony Watkinson Michael Pitton Geraldine Sergent Thomas Pfammatter Sylvain Terraz Yves Benhamou Yves Avajon Thomas Gruenberger Maria Pomoni Herbert Langenberger Marcus Schuchmann Je | 2010 | CardioVascular and Interventional Radiology2010，，1： | 1 |
| 13 | Possible small-bowel neoplasms: contrast-enhanced and water-enhanced multidetector CT enteroclysis 显示文摘 | Pilleul F Penigaud M Milot L | 2006 | Radiology2006，241，3： | 1 |
| 14 | Portal vein aneurysm :re port of two eases显示文摘 | Mhanna T Bernard P Pilleul F | 2004 | Hepato -gastroenterology2004，51，： | 1 |
| 15 | Diagnostic ERCP 显示文摘 | Ponclon T Pilleul F | 2002 | Endoscopy2002，，34： | 1 |
| 16 | Diagnosis of splanchnic artery aneurysms and pseudoaneurysms,with special reference to contrast enhanced 3D magnetic resonance angiography:a review显示文摘 | Pilleul F Beuf O | 2004 | Acta Radiol2004，45，： | 1 |
| 17 | Diagnosis of Splanchnic Artery Aneurysms and Peseudoaneurysms, with Special Reference to Contrast Enhanced 3D Magnetic Resonance Angiography: a Review显示文摘 | Pilleul F Beuf O | 2004 | Acta Radiologica2004，45，7： | 1 |
| 18 | Diagnostic ERCP显示文摘 | Ponchon T Pilleul F | 2002 | Endoscopy2002，34，1： | 1 |
| 19 | Diagnostic ERCP显示文摘 | Ponchon T Pilleul F | 2002 | Endoscopy2002，34，1： | 1 |
| 20 | Diagnostic ERCP显示文摘 | Ponchon T Pilleul F | 2002 | Endoscopy2002，34，： | 1 |
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