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| 1 | Patterns of local recurrence in rectal cancer after a multidisciplinary approach显示文摘Improvements in surgery and the application of combined approaches to fight rectal cancer have succeeded in reducing the local recurrence (LR) rate and when there is LR it tends to appear later and less often in isolation. Moreover, a subtle change in the distribution of LRs with respect to the pelvis has been observed. In general terms, prior to total mesorectal excision the most common LRs were central types (perianastomotic and anterior) while lateral and posterior forms (presa-cral) have become more common since the growth in the use of combined treatments. No differences have been reported in the current pattern of LRs as a function of the type of approach used, that is, neo-adjuvant therapies (short-term or long-course radiotherapy, orchemoradiotherapy versus extended lymphadenectomy, though there is a trend towards posterior or presacral LR in patients in the Western world and lateral LR in Asia. Nevertheless, both may arise from the same mechanism. Moreover, as well as the mode of treatment, the type of LR is related to the height of the initial tumor. Nowadays most LRs are related to the advanced nature of the disease. Involvement of the circumferential radial margin and spillage of residual tumor cells from lymphatic leakage in the pelvic side wall are two plausible mechanisms for the genesis of LR. The patterns of pelvic recurrence itself (pelvic subsites) also have important implications for prognosis and are related to the potential success of salvage curative approach. The re-operability for cure and prognosis are generally better for anastomotic and anterior types than for presacral and lateral recurrences. Overall survival after LR diagnosis is lower with radio or chemoradiotherapy plus optimal surgery approaches, compared to optimal surgery alone. | Jose M Enríquez-Navascués Nerea Borda Aintzane Liz-erazu Carlos Placer Jose L Elosegui Juan P Ciria Adelaida Lacasta Luis Bujanda | 2011 | World Journal of Gastroenterology2011，17，13： | 14 |
| 2 | Influence of Thl/Th2 cytokines and nitric oxide in murine systemic infection induced bySporothrixschenckii显示文摘 | Maia DCG Sassá MF Placeres MCP | | 0，，01： | 1 |
| 3 | Surgical approach to the locoregional recurrence of cancer of the rectum显示文摘 | Lizarazu A Enríquez-Navascués JM Placer C | | 0，，05： | 1 |
| 4 | Benign anastomotic strictures after oncologic rectal cancer surgery: results of treatment with hydrostatic dilation 显示文摘 | Placer C Urdapilteta G Markinez I | 2010 | Cir Esp2010，87，4： | 1 |
| 5 | Clinical Utility of a Multiprobe FISH Assay in Voided Urine Specimens for the Detection of Bladder Cancer and its Recurrences, Compared with Urinary Cytology显示文摘 | José Placer Blanca Espinet Marta Salido Francesc Solé Antoni Gelabert-Mas | 2002 | European Urology2002，，6： | 1 |
| 6 | Benign anastomotic strictures after oncologic rectal cancer surgery: results of treatment with hydrostatic dilation 显示文摘 | Placer C Urdapilleta G Markinez I | 2010 | Cir Esp2010，87，4： | 1 |
| 7 | Correlation between histologic findings and cytogenetic abnormalities in bladder carcinoma:a FISH study 显示文摘 | Placer J Espinet B Salido M | 2005 | Urology2005，65，5： | 1 |
| 8 | Influence of Th1/Th2 cytokines and nitric oxide in murine systemic infection induced by Sporothrix schenckii 显示文摘 | Maia D C Sassa M F Placeres M C | 2006 | Mycopathologia2006，161，1： | 1 |
| 9 | A fuzzy-neural system for identification of species-specific alarm calls of Gunnison's prairie dogs显示文摘 | Placer J Slobodchikoff C N | 2000 | Behavioural Processes2000，52，10： | 1 |
| 10 | Holmi- um laser enucleation of prostate:outcome and compli- cations of self- taught learning curve显示文摘 | Placer J Gelabert - Mas A Vallmanya F | 2009 | Urology2009，73，5： | 1 |
| 11 | Holmium laser enucleation of prostate; outcome and complications of self-taught learning curve显示文摘 | Placer J Celabert-Mas A Vallmanya F | 2009 | Urology2009，73，5： | 1 |
| 12 | Estimation of product of lipid peroxidation (malonyldi-aldehyde) in biochemical system显示文摘 | PLACER Z A CUSHMAN L JOHNSON B C | 1996 | Analytical Biochemistry1996，16，： | 1 |
| 13 | Estimation of product of lipid peroxidation (malonyl dialdehyde) in biochemical sys- tems显示文摘 | Placer Z A Cushman L L Johnson B C | 1996 | Analytical Biochemistry1996，16，： | 1 |
| 14 | Correlation between histologic findings and cytogenetic abnormalities in bladder carcinoma: a FISH study显示文摘 | Placer J Espinet B Salido M | 2005 | Urology2005，65，5： | 1 |
| 15 | Correlation between histologic findings and cytogenetic abnormalities in bladder carcinoma:a FISH study显示文摘 | Placer J Espinet B Sal ido M | 2005 | Urology2005，65，： | 1 |
| 16 | Estimation of products of lipid peroxidation(malonyl dialdehyde)in biological fluids显示文摘 | Placer ZA Cushman L Johnson BC | | 0，，： | 1 |
| 17 | Influence of Th1/Th2 cytokines and nitric oxide in murine systemic infection induced by sporothrix schenckii显示文摘 | Maia DC Sassa MF Placeres MC | 2006 | Mycopathologia2006，161，1： | 1 |
| 18 | ,Holmium laser enucleation of prostate: outcome and complications of self-taught learning curve显示文摘 | PLACER J GELABERT-MAS A VALLMANYA F | 2009 | Urology2009，73，5： | 1 |
| 19 | Usefulness of prostatic specific antigen(PSA) for diagnosis and staging of patients with prostate cancer显示文摘 | Placer J Morote J | 2011 | Arch Esp Urol2011，64，8： | 1 |
| 20 | Physiopathologic mechanisms of calculus formation in hepatic echinococcosis: a retrospective study of 63 cases 显示文摘 | Placer C Martin R Jim6nez M | 1987 | Rev Esp Ertferm Apar Dig1987，71，6： | 1 |
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