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| 1 | Diet and functional dyspepsia: Clinical correlates and therapeutic perspectives显示文摘Hypervigilance and symptoms anticipation,visceral hypersensitivity and gastroduodenal sensorimotor abnormalities account for the varied clinical presentation of functional dyspepsia(FD)patients.Many patients recognize meals as the main triggering factor;thus,dietary manipulations often represent the first-line management strategy in this cohort of patients.Nonetheless,scarce quality evidence has been produced regarding the relationship between specific foods and/or macronutrients and the onset of FD symptoms,resulting in nonstandardized nutritional approaches.Most dietary advises are indeed empirical and often lead to exclusion diets,reinforcing in patients the perception of“being intolerant”to food and self-perpetuating some of the very mechanisms underlying dyspepsia physiopathology(i.e.,hypervigilance and symptom anticipation).Clinicians are often uncertain regarding the contribution of specific foods to dyspepsia physiopathology and dedicated professionals(i.e.,dietitians)are only available in tertiary referral settings.This in turn,can result in nutritionally unbalanced diets and could even encourage restrictive eating behaviors in severe dyspepsia.In this review,we aim at evaluating the relationship between dietary habits,macronutrients and specific foods in determining FD symptoms.We will provide an overview of the evidence-based nutritional approach that should be pursued in these patients,providing clinicians with a valuable tool in standardizing nutritional advises and discouraging patients from engaging into indiscriminate food exclusions. | Marcella Pesce Martina Cargiolli Sara Cassarano Barbara Polese Barbara De Conno Laura Aurino Nicola Mancino Giovanni Sarnelli | 2020 | World Journal of Gastroenterology2020，26，5： | 14 |
| 2 | B1a lymphocytes in the rectal mucosa of ulcerative colitis patients显示文摘AIM:To assess B1a cell expression in the rectal mucosa of ulcerative colitis (UC) patients in comparison with healthy controls.METHODS:Rectal mucosa biopsies were collected from 15 UC patients and 17 healthy controls.CD5 + B cells were analysed by three colour flow cytometry from rectal mucosal samples after mechanical disaggregation by Medimachine.Immunohistochemical analysis of B and T lymphocytes was also performed.Correlations between,on the one hand,rectal B1a cell concentrations and,on the other,erythrocyte sedimentation rate and C-reactive protein levels and clinical,endoscopic and histological disease activity indices were evaluated.RESULTS:Rectal B-lymphocyte (CD19 + /CD45 +) rate and concentration were higher in UC patients compared with those in healthy controls (47.85% ± 3.12% vs 26.10% ± 3.40%,P=0.001 and 501 ± 91 cells/mm 2 vs 117 ± 18 cells/mm 2,P < 0.001);Rectal B1a cell density (CD5 + CD19 +) was higher in UC patients than in healthy controls (85 ± 15 cells/mm 2 vs 31 ± 6.7 cells/mm 2,P=0.009).Rectal B1a cell (CD5/CD19 +) rate correlated inversely with endoscopic classification (Rs=-0.637,P < 0.05).CONCLUSION:B1a lymphocytes seem to be involved in the pathogenesis of UC,however,the role they play in its early phases and in disease activity,have yet to be defined. | Lino Polese Riccardo Boetto Giuseppe De Franchis Imerio Angriman Andrea Porzionato Lorenzo Norberto Giacomo Carlo Sturniolo Veronica Macchi Raffaele De Caro Stefano Merigliano | 2012 | World Journal of Gastroenterology2012，18，2： | 2 |
| 3 | Homer 1a gene expression modulation by antipsychotic drugs: involvement of the glutamate metabotropic system and effects of D-cycloserine 显示文摘 | Polese D dd Serpis AA Ambesi-Impiobato A | 2002 | Neuropsychopharmacology2002，27，6： | 1 |
| 4 | Producer services and regional development:a policy-oriented perspective 显示文摘 | COFFEY W J POLESE M | 1989 | Paper of the Regional Science Association1989，，19： | 1 |
| 5 | Culture, Language, and the Location of High-Order Service Functions: The Case of Montreal and Toronto显示文摘 | Polese M | 2004 | Eco- nomic Geography2004，80，4： | 1 |
| 6 | Determination of pesticide residues in coconut water by liquid - liquid ex- traction and gas chromatography with electron - capture plus thermionic specific detection and solid - phase ex- traction and high - performance liquid chromatography with ultraviolet detection 显示文摘 | Brito N M Navickiene S Polese L | 2002 | J Chromatogr A2002，957，2： | 1 |
| 7 | Inspiratory muscular weakness is most evident in chronic stroke survivors with lower walking speeds 显示文摘 | Pinheiro MB Polese JC Faria CD | 2014 | Eur J Phys Rehabil Med2014，50，3： | 1 |
| 8 | The effects of walking sticks on gait kinematics and kinetics with chronic stroke survivors显示文摘 | Polese JC Teixeira-Salmela LF Nascimento LR | 2012 | Clin Biomech (Bristol Avon)2012，27，2： | 1 |
| 9 | Laser photoablation of colorectal adenomas: a 12 -year experience显示文摘 | Norberto L Polese L Angriman I | 2005 | Surg Endosc2005，19，8： | 1 |
| 10 | FIRST: Fractal indexing and retrieval system for image databases 显示文摘 | Nappi M Polese G Tortora G | 1998 | Image and Vision Computing1998，16，： | 1 |
| 11 | Hemodynamic response to seated and supine lower body negative pressure comparison with+Gz acceleration显示文摘 | Polese A Sandler H Montgomery LD | 1992 | Aviat Space Environ Med1992，63，6： | 1 |
| 12 | The intrametropolitan location of high order services : Patterns, factors and mobility in Montreal显示文摘 | Coffey W J Drolet R Polese M | 1996 | Papers in Regional Science1996，75，6： | 1 |
| 13 | The intrametropolitan location of high order services:Patterns,factors and mobility in Montreal显示文摘 | Coffey W J Drolet R Polese M | | 0，，03： | 1 |
| 14 | Upward shift of the lower range of coronary flow autoregulation in hypertensive patients with hypertrophy of the left ventricle显示文摘 | Polese A de Cesare N Montorsi P | 1991 | Circulation1991，83，3： | 1 |
| 15 | Effects of open heart surgery on respiratory mechanics显示文摘 | POLESE G LUBLI P MAZZUCCO A | 1999 | Intensive Care Med1999，25，10： | 1 |
| 16 | Urinary neopterin and kynurenine in patients submitted to surgical stress with different inhalational anesthetics (halothane orisoflurane) 显示文摘 | Marfella A Bilancio A Polese C | 1999 | International J Immunopharmacol1999，21，7： | 1 |
| 17 | The endocrine milieu and CD4 T-lymphocyte polarization during pregnancy显示文摘 | Polese B Gridelet V Araklioti E | 2014 | Front Endocrinol2014，5，： | 1 |
| 18 | Persistence of high CD40 and CD40L expression after restorative proctocolectomy for ulcerative colitis显示文摘AIM: To focus on the role of CD40 and CD40L in their pathogenesis.METHODS: We analyzed by immunohistochemistry the CD40 and CD40L expression in the pouch mucosa of 28 patients who had undergone RPC for UC, in the terminal ileum of 6 patients with UC and 11 healthy subjects. We also examined by flow cytometry the expression of CD40 by B lymphocytes and monocytes in the peripheral blood of 20 pouch patients, 15 UC patients and 11 healthy controls.RESULTS: Ileal pouch mucosa leukocytes presented a significantly higher expression of CD40 and CD40L as compared to controls. This alteration correlated with pouchitis, but was also present in the healthy pouch and in the terminal ileum of UC patients. CD40 expression of peripheral B lymphocytes was significantly higher in patients with UC and pouch, respect to controls. Increased CD40 levels in blood B cells of pouch patients correlatedwith the presence of spondyloarthropathy, but not with pouchitis, or inflammatory indices.CONCLUSION: High CD40 expression in the ileal pouch mucosa could be implied in the pathogenesis of pouchitis following proctocolectomy for UC, whereas its increased levels on peripheral blood B lymphocytes are associated with the presence of extraintestinal manifestations. | Lino Polese Imerio Angriman Giuseppe De Franchis Attilio Cecchetto Giacomo C.Sturniolo Renata D'Incà Marco Scarpa Cesare Ruffolo Lorenzo Norberto Mauro Frego Davide F D'Amico | 2005 | World Journal of Gastroenterology2005，11，34： | 1 |
| 19 | Endoscopic treatment of bile duct complications after orthotopic liver transplantation 显示文摘 | Polese L Cillo U Brolese A | 2007 | Transplant Proc2007，39，6： | 1 |
| 20 | Methods for determination of hexachlorobenzene and pentachlorophenol in soil samples显示文摘 | Polese Luciana Ribeiro Maria Lúcia | 1998 | Talanta1998，46，5： | 1 |
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