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| 1 | Management of nonfunctioning islet cell tumors显示文摘AIM: TO more clearly define the clinical and pathological characteristics and appropriate diagnosis and treatment of nonfunctioning (NFICTs) islet cell tumors, and to review our institutional experience over the last 30 years. METHODS: The records of 43 patients confirmed to have nonfunctioning islet cell tumors of pancreas were retrospectively reviewed. Survival was estimated by the Kaplan-Meier methods and potential risk factors for survival were compared with the log-rank tests. RESULTS: The mean age was 31.63 years (range, 8 to 67 years). There were 7 men and 36 women. Twentyeight patients had a confirmed diagnosis of nonfunctioning islet cell carcinoma (NFICC) and benign islet cell tumors were found in 15 patients. The most common symptoms in patients with NFICTs were abdominal pain (55.8%), nausea and/or vomiting (32.6%), fatigue (25.6%) and abdominal mass (23.3%). Preoperative ultrasonic and computed tomography localized the tumors in all patients. Forty-three NFICTs were distributed throughout the pancreas, with 21 located to the right of the superior mesenteric vessels, 10 in the body of the pancreas, 6 in the tail of the pancreas, and multiple tumors were found in one patient. Thirty-nine of 43 patients (91%) underwent surgical resection. Surgical treatment was curative in 30 patients (70%) and palliative in 9(21%). The resectability and curative resection rate in patients with NFICC of pancreas were 89% and 61%, respectively. The overall cumulative 5- and 10-year survival rates for patients with NFICC were 58.05% and 29.03%, respectively. Radical operation and diameter of cancer small than 10 cm were positive prognostic factors in females younger than 30 years old. Multivariate Cox regression analysis indicated that radical operation was the only independent prognostic factor, P=0.007. CONCLUSION: Nonfunctioning islet cell tumors of pancreas are found mainly in young women. The long-term results for patients undergone surgery, especially curative resection are good. | HanLiang PuWang Xiao-NaWang Jia-CangWang Xi-ShanHao | 2004 | World Journal of Gastroenterology2004，10，12： | 5 |
| 2 | Synthesis and characterization of folate conjugated chitosan and cellular uptake of its nanoparticles in HT-29 cells显示文摘 | Puwang Li Yichao Wang Fanbo Zeng Lijue Chen Zheng Peng Ling Xue Kong | 2011 | Carbohydrate Research2011，，6： | 1 |
| 3 | Light-absorbing copolymers of polyimides as effi显示文摘Polyimide(PI),an important engineering polymer with a rigid chemical structure,readily has excellent chemical stability,heat resistance,and electrical insulation but lacks broadband photothermal properties.Herein,we design and synthesize PI copolymers that embrace intrinsic photothermal properties by using two diamine monomers of(Z)-2,3-bis(4-aminophenyl)acrylonitrile(CNDA)and 4,4-diphenyldiamine(NDA)with strong ultraviolet(UV),and near-infrared(NIR)absorption capabilities,respectively.Tuning the molar ratio of the two diamines can modulate UV and NIR light absorption and regulate the intrinsic photothermal properties of PIs.After condensation with pyromellitic dianhydride,the resulting PI-0.5 with a unit molar ratio of CNDA:NDA=1 shows the best photothermal efficiency.PI-0.5 is used to construct 3D steam generators with vertically dried channels by a freeze-drying method.The 3D steam generators show a good water evaporation rate and continuously operate with excellent stability under varying salinity and pH conditions.The synthetic design herein suggests that PI can be molecularly engineered to be intrinsic photothermal materials,expanding the properties and applications of existing PIs. | Shi-Qin Li Yuan Deng Jiang Huang PuWang Guoliang Liu He-Lou Xie | 2023 | Aggregate2023，4，5： | 0 |
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