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| 1 | Numerical investigation of the effectiveness of radon control measures in cave mines显示文摘Ventilation is one of the radon control measures in an underground working environment.However,the dynamics related to the cave mining methods particularly in block/panel cave mines,complicate the design of effective ventilation system,and implementation.Events such as hang ups(in the drawbells),leakage from old workings,and changes in cave porosity lead to differing response of an existing ventilation designs.However,it is difficult to investigate these conditions at the mine or with a laboratory scale study.Therefore,this study develops a discrete model to investigate the impact of different radon control measures in cave mines using computational fluid dynamics techniques.We considered two ventilation conditions for a fully developed cave:with and without the undercut ventilation.For each of the two conditions,we studied four parameters:airflow distribution through the production drifts,radon distribution through the production drifts,the effect of increasing airflow on radon concentration,and the effect of a cave top negative pressure on radon distribution.The results show that:the undercut ventilation significantly increases the radon concentration in the production drift;the growth of radon concentration through the production drift is nonlinear(oscillating pattern);maintaining a negative pressure on top of the cave is more effective at mitigating radon exposure,when the undercut ventilation is active;and increase in air volume flow rate decreases radon concentration in most regions,however,there might be regions with significant radon accumulation due to pressure variation across the drifts.These findings provide vital information for designing an effective ventilation system and for proactive implementation of radon control measures in cave mines. | Kayode Ajayi Khosro Shahbazi Purushotham Tukkaraja Kurt Katzenstein | 2019 | International Journal of Mining Science and Technology2019，29，3： | 3 |
| 2 | Prediction of airway resistance in panel cave mines using a discrete and continuum model显示文摘The configuration of an airway(or production drift)in panel cave mines is different from the typical(straight)mine airway designs.The drawpoints are connected to the airway(cross-cuts),which allows airflow from the cave into the airway or air loss from the airway into the cave due to the ventilation approach and cave porosity.These affect airflow in the production drifts,but it is difficult to investigate these conditions from field or laboratory scaled studies.Therefore,this study develops discrete and continuum computational fluid dynamics(CFD)models to study the effects of the ventilation approach and cave porosity on the airway resistance.Our findings show that:with active undercut ventilation,a unique resistance model is required for the airway in panel cave mines;and an increase in cave porosity decreases the drift’s resistance.These findings provide essential tools for a panel cave ventilation design. | Kayode M.Ajayi Khosro Shahbazi Purushotham Tukkaraja Kurt Katzenstein | 2019 | International Journal of Mining Science and Technology2019，29，5： | 2 |
| 3 | Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation显示文摘 | Aparna Purushotham Thaddeus T. Schug Qing Xu Sailesh Surapureddi Xiumei Guo Xiaoling Li | 2009 | Cell Metabolism2009，，4： | 2 |
| 4 | Bioremediation of anthracene contaminated soil in bio-slurry phase reactor operated in periodic discontinuous batch mode显示文摘 | PRASANNA D VENKATA Mohan S PURUSHOTHAM R B | 2008 | Journal of Hazardous Materials2008，，153： | 1 |
| 5 | Neoadjuvant chemotherapy in breast Cancer显示文摘 | CHARFARE H LIMONGELLI S PURUSHOTHAM A D | 2005 | Br J Surg2005，92，1： | 1 |
| 6 | In vivo imaging of tumorapoptosis using histone HI-targeting peptide 显示文摘 | Wang K Purushotham S Lee Ti | 2010 | J Control Re-lease2010，148，3： | 1 |
| 7 | Neoadjuvantchemotherapy in breast cancer显示文摘 | Charfare H Limongelli S Purushotham AD | 2005 | Br J Surg2005，92，1： | 1 |
| 8 | Mor- bidity after sentinel lymph node biopsy in primary breast cancer: results from a randomized controlled trial 显示文摘 | Purushotham AD Upponi S Klevesath MB | 2005 | J Clin Oncol2005，23，19： | 1 |
| 9 | Ex situ bioremediation of pyrene contaminated soil in bio-slurry phase reactor operated in periodic discontinuous batch mode:Influence of bioaugmentation显示文摘 | VENKATA M S PRASANNA D PURUSHOTHAM R B | 2008 | International Biodeterioration & Biodegradation2008，，62： | 1 |
| 10 | Lymphoedema following surgery for breast cancer显示文摘 | Pain SJ Purushotham AD | 2000 | Br J Surg2000，87，9： | 1 |
| 11 | A note on fire resistive cum antiseptic composition and fire resistive paint显示文摘 | PURUSHOTHAM A PANDE J N SOOD J S | 1963 | J Timb Dev Assoc(India)1963，，9： | 1 |
| 12 | Detection of intraoperative tumor cell dissemination in patients with breast cancer by use of reverse transcription and polymerase chain reaction显示文摘 | Brown DC Purushotham AD Birnie GD | 1995 | Surgery1995，117，1： | 1 |
| 13 | Neoadjuvant chemotherapy in breast cancer显示文摘 | Charfare H Limongelli S Purushotham AD | 2005 | Br J Surg2005，92，1： | 1 |
| 14 | Immediate breast reconstruction after mastectomy for cancer显示文摘 | Malata CM McIntosh SA Purushotham AD | 2000 | Br J Surg2000，87，11： | 1 |
| 15 | The infarct core is well represented by the acute diffusion lesion:sustained reversal is infrequent显示文摘 | CAMPBELL B C PURUSHOTHAM A CHRISTENSEN S | 2012 | J Cereb Blood Flow Metab2012，32，1： | 1 |
| 16 | Lymph node status and breast cancer-related lymphedema 显示文摘 | Purushotham AD Bennett Britton TM Klevesath MB | 2007 | Ann Surg2007，246，： | 1 |
| 17 | Hepatocyte-spe- cific deletion of SIRT1 alters fatty acid metabolism and re- sults in hepatic steatosis and inflammation 显示文摘 | Purushotham A Schug TY Xu Q | 2009 | Cell Metab2009，9，4： | 1 |
| 18 | Thermoresponsive magnetic composite nanomaterials for multimodal cancer therapy显示文摘 | S. Purushotham R.V. Ramanujan | 2009 | Acta Biomaterialia2009，，2： | 1 |
| 19 | Detection of intraopetative tumor cell dissemination in patients with breast cancer by use of reverse transcription and polymerase chain reaction显示文摘 | Brown DC Purushotham AD Birnie GD | | Surgery0，117，1： | 1 |
| 20 | A 1 -year variation in distress, and illness perceptions, after treatment for breast cancer 显示文摘 | Millar K Purushotham AD prospective study of individual McLatchie E | 2005 | J Psychosom Res2005，58，4： | 1 |
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