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| 1 | Prediction of the severity of acute pancreatitis on admission by urinary trypsinogen activation peptide: A meta-analysis显示文摘AIM: To undertake a meta-analysis on the value of urinary trypsinogen activation peptide (uTAP) in predicting severity of acute pancreatitis on admission. METHODS: Major databases including Medline, Embase, Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials in the Cochrane Library were searched to identify all relevant studies from January 1990 to January 2013. Pooled sensitivity, specificity and the diagnostic odds ratios (DORs) with 95%CI were calculated for each study and were compared to other systems/biomarkers if mentioned within the same study. Summary receiver-operating curves were conducted and the area under the curve (AUC) was evaluated. RESULTS: In total, six studies of uTAP with a cut-off value of 35 nmol/L were included in this meta-analysis. Overall, the pooled sensitivity and specificity of uTAP for predicting severity of acute pancreatitis, at time of admission, was 71% and 75%, respectively (AUC = 0.83, DOR = 8.67, 95%CI: 3.70-20.33). When uTAP was compared with plasma C-reactive protein, the pooled sensitivity, specificity, AUC and DOR were 0.64 vs 0.67, 0.77 vs 0.75, 0.82 vs 0.79 and 6.27 vs 6.32, respectively. Similarly, the pooled sensitivity, specificity, AUC and DOR of uTAPvs Acute Physiology and Chronic Health Evaluation Ⅱ within the first 48 h of admission were found to be 0.64 vs 0.69, 0.77 vs 0.61, 0.82 vs 0.73 and 6.27vs 4.61, respectively. CONCLUSION: uTAP has the potential to act as a stratification marker on admission for differentiating disease severity of acute pancreatitis. | Wei Huang Kiran Altaf Tao Jin Jun-Jie Xiong Li Wen Muhammad A Javed Marianne Johnstone Ping Xue Christopher M Halloran Qing Xia | 2013 | World Journal of Gastroenterology2013，19，28： | 7 |
| 2 | Comparative studies on alkylation of phenol with tertbutyl alcohol in the presence of liquid or solid catalysts in ionil liquids显示文摘 | SHEN Hao - yu Zaher M A CHI Bun - ching XIA Qing - hua | 2004 | Journal of molecular catalysis A: chemcal2004，212，： | 1 |
| 3 | The inflammatory response in stroke 显示文摘 | WANG QING TANG XIANNAN YENARI M A | 2007 | J Neuroimmunol2007，184，12： | 1 |
| 4 | Studying the Fault- Detection Effective- ness oI GUI Test Cases for Rapidly Evolving Software显示文摘 | Memon A M Xie Qing | 2005 | IEEE Transactions on Software Engineering2005，31，10： | 1 |
| 5 | Using a Pilot Study to Derive a GUI Model for Automated Testing显示文摘 | Xie Qing Memon A M | 2008 | ACM Transactions on Soft- ware Engineering And Methodology2008，18，2： | 1 |
| 6 | On-line partial filling micellar electrokinetic chromatography - electrospray ionization mass spectrometry显示文摘 | NELSON W M TANG Qing HARRATA A K | 1996 | J Chromatogr: A1996，749，12： | 1 |
| 7 | Using a Pilot Study to Derive a GUI Model for Automated Testing显示文摘 | Xie Qing Memon A M | 2008 | ACM Transactions on Software Engineering And Methodology2008，18，2： | 1 |
| 8 | Studying the Fault-detection Effectiveness of GUI Test Cases for Rapidly Evolving Software显示文摘 | Memon A M Qing Xie | 2005 | IEEE Transactions on Software Engineering2005，31，10： | 1 |
| 9 | Monitoring the Integrity of Filament Wound Structure Using Built-Insensor Networks显示文摘 | Lin M Kumar A Qing X L | 2003 | Industrial and Commercial Applications of Smart Structures Technologies2003，5054，： | 1 |
| 10 | Smart layer and smart suitcase for structural health monitoring applications显示文摘 | LIN M QING X L KUMAR A | 2001 | Smart Structures and Materials Proceedings of SPIE2001，4332，： | 1 |
| 11 | Timing, duration, and transitions of the last interglacial Asian monsoon 显示文摘 | Yuan Daoxian Cheng Hai Edwards R L Dykoski C A Kelly M J Zhang Meiliang Qing Jiaming Lin Yushi Wang Yongjin Wu Jiangyin Dorale J A An Zhisheng Cai Yanjun | 2004 | Science2004，304，5670： | 1 |
| 12 | Designing and Comparing Automated Test Oracles for GUI-Based Software Applications显示文摘 | Xie Qing Memon A M | 2007 | ACM Trans on Software Engineering and Methodology2007，16，1： | 1 |
| 13 | Smart layer and smart suitcase for structural health monitoring applications显示文摘 | LIN M QING X KUMAR A | 2001 | Smart Structures and Materials Conference Proceedings of SPIE2001，4332，： | 1 |
| 14 | Monitoring the integrity of filament wound structures using builtin sensor networks显示文摘 | LIN M KUMAR A QING Xin-lin | 2003 | Smart Structures and Materials Proceedings of SPIE2003，5054，： | 1 |
| 15 | Clinical utility of the reticulocyte hemoglobin content in the diagnosis of iron deficiency 显示文摘 | MAST A E BLINDER M A QING L | 2002 | Blood2002，99，4： | 1 |
| 16 | A high- resolution, absolule-dated Holoeene and deglacial Asian monsoon reemxl from Dongge Cave, China显示文摘 | DYKOSKI C A EDWARDS R L CHENG H YUAND D X CAI Y J ZHANG M L LIN Y S QING J M AN Z S REVENAUGH J | 2005 | Earth and Planetary Science Letters2005，233，： | 1 |
| 17 | Circulating [alpha]Klotho influences phosphate handling by controlling FGF23 production显示文摘 | Smith Rosamund C O’Bryan Linda M Farrow Emily G Summers Lelia J Clinkenbeard Erica L Roberts Jessica L Cass Taryn A Saha Joy Broderick Carol Ma Y Linda Zeng Qing Qiang Kharitonenkov Alexei Wilson Jonathan M Guo Qianxu Sun Haijun Allen Matt | 2012 | Journal of Clinical Investigation2012，，12： | 1 |
| 18 | A high- resolution, absolute-dated Holocene and deglacial Asian monsoon record from Dongge Cave, China 显示文摘 | Dykoski C A Edwards R L Cheng H Yuan D X Cai Y J Zhang M L Lin Y S Qing J M An Z S Revenaugh J | 2005 | Earth Planet Sci Lett2005，233，12： | 1 |
| 19 | Degradation of BACE by the ubiquitin-proteasome pathway显示文摘 | Qing H Zhou W Christensen M A | 2004 | Faseb2004，18，13： | 1 |
| 20 | Identification of NGAL as a novel early urinary marker for ischemic renal injury显示文摘 | MISHRA J QING M PRADA A | 2003 | J Am Soc Nephrol2003，14，10： | 1 |
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