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| 1 | Biodistribution of fullerene derivative C_(60)(OH)_x(O)_y显示文摘The biological behavior of fullerene derivatives shows their considerable potential application in medicine field. To understand the biodistribution of C60 derivatives as drugs or drug carriers, a simple water-soluble derivative C60(OH)x(O)y was labeled with 99mTc. A r-counter and a single photo emission computed tomography (SPECT) were used to assess the biodistribution and metabolism of the labeled compound in mice and rabbits, respectively. The results showed that the compound could be absorbed rapidly by tissues, especially by coronal bone, breastbone, backbone, extremity honeycomb, liver and spleen. The clearance was slow from all tissues except for brain. The compound might be excreted through urine and enteron. The biodistribution shows some difference from that of Yamago et al. In this note, we discuss the possible reason leading to the difference. Further study is needed to find out to what extent the C60 itself determines the biodistribution of derivatives. | LI Qingnuan, XIU Yan, ZHANG Xiaodong, LIU Ruili, DU Qianqian, SUN Xiaoguang, CHEN Shaoliang & LI Wenxin1. Shanghai Institute of Nuclear Research, Chinese Academy of Sciences, Shanghai 201800, China 2. Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China | 2001 | Chinese Science Bulletin2001，46，19： | 5 |
| 2 | Preparation of (188Re) ReAEDP and its biodistribution studies显示文摘 | Qingnuan L Xiaodong Z Rong S | | 0，，06： | 1 |
| 3 | Production of no-carrier-added ^186 Re via deuteron induced reactions on isotopically enriched 186W 显示文摘 | Xiaodong Zhanga Qingnuan Lia Wenxin Lia | 2001 | Applied Radiation and Isotopes2001，54，： | 1 |
| 4 | Investigation of solid-state reaction by terahertz time-domain spectroscopy显示文摘Terahertz time-domain spectroscopy(THz-TDS)was utilized to investigate the solid-state reaction between L(+)-Tartaric acid and sodium hydrogen carbonate.Solid sodium hydrogen L(+)-tartrate monohydrate was synthesized efficiently by mechanical grinding,which is particularly sustainable and environmentally benign.Distinct THz absorptions were observed for pure reactants and the proposed product.The reaction process could be clearly visualized by THz spectral patterns of the reaction mixtures at different grinding time.The observed results were further confirmed by synchrotron radiation X-ray powder diffraction(SRXRPD)and Fourier transform infrared (FT-IR)spectroscopy.The study demonstrates that THz-TDS is an effective novel tool to monitor solid-state reactions in pharmaceutical industry. | LIU Xiaohong ZHAO Hongwei WU Yuting LI Qingnuan ZHU Zhiyong | 2011 | Nuclear Science and Techniques2011，22，3： | 0 |
| 5 | SYNTHESIS OF NOVEL ORGANOPHOSPHORUS C_(60) DIMERS显示文摘Carbon bridged organophosphorus C60 dimers were obtained by the reaction of aminome- thylenebisphosphonate anion with C60 and fully characterized by 1HNMR, 31PNMR, 13CNMR, FT- MALDI-MS, FT-IR, UV-Vis, DEPT and HMBC, and the dimeric compounds undergo hydrolysis by using TMSI. | YIN duanjuan LI Qingnuan LI Wenxin | 2006 | Chinese Science Bulletin2006，51，4： | 0 |
| 6 | Development and Challenges of Electrode Ionomers Used in the Catalyst Layer of Proton-Exchange Membrane Fuel Cells:A Review显示文摘The electrode ionomer plays a crucial role in the catalyst layer(CL) of a proton-exchange membrane fuel cell(PEMFC) and is closely associated with the proton conduction and gas transport properties,structural stability,and water management capability.In this review,we discuss the CL structural characteristics and highlight the latest advancements in ionomer material research.Additionally,we comprehensively introduce the design concepts and exceptional performances of porous electrode ionomers,elaborate on their structural properties and functions within the fuel cell CL,and investigate their effect on the CL microstructure and performance.Finally,we present a prospective evaluation of the developments in the electrode ionomer for fabricating CL,offering valuable insights for designing and synthesizing more efficient electrode ionomer materials.By addressing these facets,this review contributes to a comprehensive understanding of the role and potential of electrode ionomers for enhancing PEMFC performance. | Qingnuan Zhang Bo Wang | 2023 | Transactions of Tianjin University2023，29，5： | 0 |
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