3篇
您的检索式：作者名="Qiu Chunli"
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| 1 | Specific targeting of nasopharyngeal carcinoma cell line CNE1 by C225-conjugated ultrasmall superparamagnetic iron oxide particles with magnetic resonance imaging显示文摘临床的目标体积(CTV ) 的一个精确定义为在鼻咽的癌(NPC ) 的放射疗法的应用程序是必要的处理。指向对比代理人(C225-USPIO ) 的新奇表皮的生长因素受体(EGFR ) 被结合 ultrasmall superparamagnetic 设计有 cetuximab (C225 ) 的氧化铁(USPIO ) nanoparticles, non-invasively 定义肿瘤的 CTV。到 NPC 房间线 CNE1 的 C225-USPIO 的 immunobinding 活动被流动 cytometry 和 immunofluorescence 证实。在 CNE1 房间的 C225-USPIO 的时间依赖者累积用普鲁士的蓝染色被评估。指向的成为主观和 C225-USPIO 的 subcellular 本地化被传播电子显微镜证实。结果显示了明确地在 CNE1 房间的表面上绑在 EGFR 的那 C225-USPIO 并且被收起进房间。由 CNE1 房间的 C225-USPIO 的举起与时间显著地增加了,当时与人的 IgG-USPIO 相比。另外, 4.7 T 磁性的回声成像(MRI ) 随着时间的过去表明 C225-USPIO 有一个能力在 CNE1 房间积累,与在 MRI T2 加权的信号紧张的结果的显著减少。这些调查结果当一个 MRI 对比代理人和罐头被采用 non-invasively 与 EGFR overexpression 检测早阶段的 NPC,暗示 C225-USPIO 有潜力。这为与混合物在 vivo 实验开始提供足够的理论基础。 | Dongbo Liu Chunli Chen Guangyuan Hu Qi Mei Hong Qiu Guoxian Long Guoqing Hu | 2011 | Acta Biochimica et Biophysica Sinica2011，43，4： | 10 |
| 2 | Review on status of groundwater database and application prospect in deep-time digital earth plan显示文摘Groundwater is an important water resource.The total amount of active groundwater in a hydrological cycle is about 3.5 times that of the total amount of surface water.The information in the deep groundwater records the material exchange and dynamics in the earth’s evolution,which is an important aspect of the Deep-Time Digital Earth(DDE)plan.In recent years,scientists have discussed the distribution of transboundary aquifers and the environmental significance of groundwater resources through groundwater databases established by international organizations,such as the Global Groundwater Information System and the chronicles consortium,and national institutes,such as national geological surveys.The application of the groundwater database in the DDE plan,however,has been limited by the management,interactivity,and monitoring method of the groundwater data.The ability to further integrate data that are private and scattered across research institutions and individuals,while establishing an open,unified,and shared groundwater data platform,is essential to enhance our understanding of groundwater,ranging from shallow to deep water,which is a goal of the DDE plan.In this study,we introduced the current situation of groundwater database operations in domestic and international research and provided frontier research with groundwater big data.Considering the related objectives of the DDE plan and the limitations of existing groundwater databases,we proposed an improvement plan and new prospects for applying groundwater databases in the research of the deep earth. | Wenkai Qiu Teng Ma Yanxin Wang Jianmei Cheng Chunli Su Junxia Li | 2022 | Geoscience Frontiers2022，13，4： | 1 |
| 3 | Risk Regionalization of Low-temperature Disasters for Flue-cured Tobacco Planting in Qujing Area Based on GIS显示文摘There is a prominent,complex and diverse three-dimensional climate and a variety of meteorological disasters in Qujing area. The risk zoning of low-temperature disasters for flue-cured tobacco planting in Qujing area was studied to provide reference for drawing on advantages and avoiding disadvantages in flue-cured tobacco planting,disaster reduction,and disaster relief services. According to the production practice of fluecured tobacco and local climate analysis,it was determined that flue-cured tobacco in Qujing area was very vulnerable to low temperature during the seedling stage( from early February to middle April) and in the mature period( from early July to early September). Based on the quantitative analysis and evaluation of risk of disaster-causing factors,sensitivity of disaster-breeding environment,vulnerability of carriers,and disaster prevention and reduction capability,a risk assessment model of meteorological disasters was established to precisely evaluate and zone the risk of low-temperature disasters for flue-cured tobacco planting in allusion to the seedling and mature stage in Qujing area by using GIS technology. The risk of lowtemperature disasters for flue-cured tobacco planting during the two periods was divided into four grades,namely low,medium,high and very high risk. | Pu Jicun Zhang Maosong Yuan Jiafeng Qiu Chunli Xie Yan | 2018 | Meteorological and Environmental Research2018，9，1： | 0 |
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