| 1 | Effect of Laminarin on Growth and Immunity of Pearl Gentian Grouper显示文摘[Objective] The paper was to study the effects of laminarin on growth performance and immunity of pearl gentian groupers. [Method] Four separate30 m2 concrete pools were used as a closed circulating water aquaculture system for the experiment. Simultaneously,approximately 1 800 groupers were placed in each of the two pools for treatment or control. The initial weight of the individual fish was( 275. 55 ± 29. 79) g. They were fed with either a control diet or one containing 0. 6% laminarin in the pools for 66 d. [Result]At the end of the feeding trial,the weight gain of the groupers in treatment group was increased by 29. 03%( P <0. 05),the specific growth ratio was increased by 23. 88%( P <0. 05),and the feed conversion rate was decreased by 15. 20%( P <0. 05) compared to control group,while there was no significant difference in muscle nutritional components between treatment group and control group( P > 0. 05). For each kilogram weight gain of an individual fish,the cost of the treatment diet was 1. 96 yuan less than that of control diet,i. e.,a reduction of 12. 54%. On the other hand,the activities of alkaline phosphatase( AKP),lysozyme( LZM) and total superoxide dismutase( T-SOD) of the groupers in treatment group were significantly higher than those in control group( P < 0. 05). [Conclusion] Addition of 0. 6% laminarin in the regular feed would improve the growth performance and immunity of pearl gentian groupers in aquaculture. | Lin Jianbin Liang Ping Zhu Qingguo Qiu Manli | 2017 | Animal Husbandry and Feed Science2017，9，4： | 2 |
| 2 | Aberrant single-subject morphological brain networks in first-episode,treatment-naive adolescents with major depressive disorder显示文摘Background:Neuroimaging-based connectome studies have indicated that major depressive disorder(MDD)is associated with dis-rupted topological organization of large-scale brain networks.However,the disruptions and their clinical and cognitive relevance are not well established for morphological brain networks in adolescent MDD.Objective:To investigate the topological alterations of single-subject morphological brain networks in adolescent MDD.Methods:Twenty-five first-episode,treatment-naive adolescents with MDD and 19 healthy controls(HCs)underwent T1-weighted magnetic resonance imaging and a battery of neuropsychological tests.Single-subject morphological brain networks were constructed separately based on cortical thickness,fractal dimension,gyrification index,and sulcus depth,and topologically characterized by graph-based approaches.Between-group differences were inferred by permutation testing.For significant alterations,partial correla-tions were used to examine their associations with clinical and neuropsychological variables in the patients.Finally,a support vector machine was used to classify the patients from controls.Results:Compared with the HCs,the patients exhibited topological alterations only in cortical thickness-based networks character-ized by higher nodal centralities in parietal(left primary sensory cortex)but lower nodal centralities in temporal(left parabelt complex,right perirhinal ectorhinal cortex,right area PHT and right ventral visual complex)regions.Moreover,decreased nodal centralities of some temporal regions were correlated with cognitive dysfunction and clinical characteristics of the patients.These results were largely reproducible for binary and weighted network analyses.Finally,topological properties of the cortical thickness-based net-works were able to distinguish the MDD adolescents from HCs with 87.6%accuracy.Conclusion:Adolescent MDD is associated with disrupted topological organization of morphological brain networks,and the disrup-tions provide potential biomarkers for diagnosing and monitoring the disease. | Xiaofan Qiu Junle Li Fen Pan Yuping Yang Weihua Zhou Jinkai Chen Ning Wei Shaojia Lu Xuchu Weng Manli Huang Jinhui Wang | 2023 | Psychoradiology2023，3，1： | 0 |
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