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| 1 | Role of mi RNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer显示文摘Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large number of upregulated oncogenic mi RNAs and downregulated tumour-suppressor mi RNAs in this type of cancer. In this review, we provide an overview of the role of mi RNAs, pointing to their potential to be useful as diagnostic and/or prognostic biomarkers in gastric cancer. Moreover, we discuss the influence of polymorphisms and epigenetic modifications on mi RNA activity. | Kelly Cristina da Silva Oliveira Taíssa Maíra Thomaz Araújo Camila Inagaki Albuquerque Gabriela Alcantara Barata Carolina Oliveira Gigek Mariana Ferreira Leal Fernanda Wisnieski Fernando Augusto Rodrigues Mello Junior André Salim Khayat Paulo Pimentel de Assumpcao Rommel Mário Rodriguez Burbano Marília Cardoso Smith Danielle Queiroz Calcagno | 2016 | World Journal of Gastroenterology2016，22，35： | 11 |
| 2 | Interrelationship between chromosome 8 aneuploidy,C-MYC amplification and increased expression in individuals from northern Brazil with gastric adenocarcinoma显示文摘AIM: To investigate chromosome 8 numerical aberra- tions, C-MYC oncogene alterations and its expression in gastric cancer and to correlate these findings with histo- pathological characteristics of gastric tumors. METHODS: Specimens were collected surgically from seven patients with gastric adenocarcinomas. Immu- nostaining for C-MYC and dual-color fluorescence in situ hybridization (FISH) for C-MYC gene and chromosome 8 centromere were performed. RESULTS: All the cases showed chromosome 8 aneu- ploidy and C-MYC amplification, in both the diffuse and intestinal histopathological types of Lauren. No significant difference (P < 0.05) was observed between the level ofchromosome 8 ploidy and the site, stage or histological type of the adenocarcinomas. C-MYC high amplification, like homogeneously stained regions (HSRs) and double minutes (DMs), was observed only in the intestinal-type. Structural rearrangement of C-MYC, like translocation, was observed only in the diffuse type. Regarding C-MYC gene, a significant difference (P < 0.05) was observed between the two histological types. The C-MYC protein was expressed in all the studied cases. In the intestinal- type the C-MYC immunoreactivity was localized only in the nucleus and in the diffuse type in the nucleus and cytoplasm. CONCLUSION: Distinct patterns of alterations between intestinal and diffuse types of gastric tumors support the hypothesis that these types follow different genetic path- ways. | Danielle Queiroz Calcagno Mariana Ferreira Leal Aline Damaceno Seabra Andre Salim Khayat Elizabeth Suchi Chen Samia Demachki Paulo Pimentel Assumpcao Mario Henrique Girao Faria Silvia Helena Barem Rabenhorst Márcia Valéria Pitombeira Ferreira Marília de Arruda Cardoso Smith Rommel Rodríguez Burbano | 2006 | World Journal of Gastroenterology2006，12，38： | 9 |
| 3 | How to manage inflammatory bowel disease during the COVID-19 pandemic:A guide for the practicing clinician显示文摘Managing inflammatory bowel disease(IBD)during the coronavirus disease 2019(COVID-19)pandemic has been a challenge faced by clinicians and their patients,especially concerning whether to proceed with biologics and immunosuppressive agents in the background of a global outbreak of a highly contagious new coronavirus(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2).The knowledge about the impact of this virus on patients with IBD,although it is still scarce,is rapidly evolving.In particular,concerns surrounding medications’impact for IBD on the risk of acquiring SARS-CoV-2 infection or developing COVID-19,and potentially exacerbate viral replication and the COVID-19 course,are a current thinking of both practicing clinicians and providers caring for patients with IBD.Managing patients with IBD infected with SARS-CoV-2 depends on both the clinical activity of the IBD and the occasional development and severity of COVID-19.In this review,we summarize the current data regarding gastrointestinal involvement by SARS-CoV-2 and pharmacologic and surgical management for IBD concerning this infection,and the COVID-19 impact on both the patient's psychological functioning and endoscopy services,and we concisely summarize the telemedicine roles during the COVID-19 pandemic. | Júlio Maria Fonseca Chebli Natália Sousa Freitas Queiroz Adérson Omar Mourão Cintra Damião Liliana Andrade Chebli Márcia Henriques de Magalhães Costa Rogério Serafim Parra | 2021 | World Journal of Gastroenterology2021，27，11： | 2 |
| 4 | Anti- Helicobacter pylori and urease inhibitory activities of resveratrol and red wine显示文摘 | Luísa Paulo Mónica Oleastro Eugenia Gallardo Jo?o António Queiroz Fernanda Domingues | 2011 | Food Research International2011，，4： | 1 |
| 5 | Robust adaptive asymptotic tracking of nonlinear systems with additive disturbance 显示文摘 | Cai Z de Queiroz M S Dawson D M | 2006 | 1EEE Transactions on Automatic Control2006，51，3： | 1 |
| 6 | ATR-FTIR: studies of poly ( propylene oxide)/polybutadiene hi-soft segment urethane/urea membranes 显示文摘 | Queiroz D P De Pinho M N Dias C | 2003 | Macromolecules2003，36，11： | 1 |
| 7 | Xylitol production from eucalyptus wood hydrolysates extracted with organic solvents显示文摘 | Costa Queiroz R H Melchior E de Souza A M | 1997 | Process Biochemistry1997，32，7： | 1 |
| 8 | Electrochemical, chemical and morphological characterization of galvannealed steel coating显示文摘 | Queiroz F M Costa I | 2007 | Surface and Coating Technology2007，201，： | 1 |
| 9 | The influence of cul-ture conditions on mycelial structure and eellulase production by Trichoderma reese/Rut C-30显示文摘 | Domingues F C Queiroz J A Cabral J M S | 2000 | Enzyme and Microbial Technolo-gy2000，26，5： | 1 |
| 10 | Adaptive vibration control of an axially moving string 显示文摘 | DE QUEIROZ M S DAWSON D M RAHN C D | 1999 | Journal of Vibration and Acoustics1999，121，1： | 1 |
| 11 | Quatemion-Based Adaptive Attitude Tracking Controller Without Velocity Measurements 显示文摘 | Costic B T Dawson D M Queiroz M S Kapola V | 2001 | Journal of Guidance Control and Dynamics2001，24，6： | 1 |
| 12 | Silica-based nano-coating on zirconia surfaces using reactive magnetron sputtering:effect on chemical adhesion of resin cements显示文摘 | Queiroz JR Massi M Nogueira L Jr | 2013 | J Adhes Dent2013，15，2： | 1 |
| 13 | Optimization of the Liquid-Liquid Extraction Method and Low Temperature Purification (LLE-LTP) for Pesticide Residue Analysis in Honey Samples by Gas Chromatography 显示文摘 | Pinho G P de Neves A A Queiroz M E L R de | 2010 | Food Control2010，21，10： | 1 |
| 14 | Quaternion-based adaptive attitude tracking controller without velocity measurements显示文摘 | Costic B T Dawson D M Queiroz M S Kapila V | 2001 | Journal of Guidance Control and Dynamics2001，24，6： | 1 |
| 15 | High altitude headache 显示文摘 | Queiroz L P Rapoport A M | 2007 | Curr Pain Headache Rep2007，11，4： | 1 |
| 16 | Nodal analysis of switched-current filters显示文摘 | DE QUEIROZ A C M PINHEIRO P R M CALDBA L P | 1993 | IEEE Transactions on Circuits And Systems-Ⅱ Analog And Digital Signal Procesing1993，40，1： | 1 |
| 17 | Comparison of greenhouse gas emissions from an old tropical reserw~ir with those from other reservoirs worldwide显示文摘 | DUCHEMIN E LUCOTTE M QUEIROZ A G | 2000 | Verh Int Verein Limno2000，27，： | 1 |
| 18 | Adaptive nonlinear control of multiple spacecraft formation flying显示文摘 | Queiroz de M S Kapila V Yan Q | 2000 | J of Guidance Control and Dynamics2000，23，3： | 1 |
| 19 | Geographic distribution of vacA allelic types of Helicobacter pylori显示文摘 | Leen–Jan Van Doorn Céu Figueiredo Francis Mégraud Salvador Pena Peter Midolo Dulciene Maria De Magalh?es Queiroz Fátima Carneiro Bart Vanderborght Maria Da Glória F. Pegado Ricardo Sanna Wink De Boer Peter M. Schneeberger Pelayo Correa Enders K.W. Ng John | 1999 | Gastroenterology1999，，4： | 1 |
| 20 | Analysis of the coffee harvesting process using an electromagnetic shaker 显示文摘 | Santos F L Queiroz D M Pinto F A C | 2010 | Acta Scientiarum Agronomy2010，32，37： | 1 |
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