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| 1 | 中国沿海两例食用织纹螺中毒事件中织纹螺体内毒素分析显示文摘近年来,因食用织纹螺(Nassariusspp.)导致的中毒事件在中国沿海屡有发生。由于中毒患者的症状与麻痹性贝毒中毒症状相似,因此,许多中毒事件被归咎于麻痹性贝毒,认为织纹螺中的毒素与邻近海域的有毒赤潮有关,但也有研究发现螺体内存在河豚毒素。对此,本研究应用亲水性相互作用色谱柱建立了河豚毒素的液相色谱-质谱联用分析方法,对造成2002年和2003年两次中毒事件的织纹螺样品进行分析。结果表明,两批织纹螺样品中均含有高浓度的河豚毒素及其衍生物,包括三脱氧河豚毒素、脱水河豚毒素和单加氧河豚毒素等,而且两个织纹螺样品中的毒素组成非常相似。因此,导致这两起中毒事件的致毒因子是河豚毒素及其衍生物。江苏和福建两地织纹螺中毒素组成的相似性显示两地织纹螺可能具有相同或相近的毒素来源。 | 于仁成 周名江 李爱峰 张清春 王云峰 李钧 颜天 Michael Quilliam Bernd Luckas | 2007 | 中国水产科学2007，14，5： | 21 |
| 2 | 利奈唑胺和万古霉素治疗甲氧西林耐药金黄色葡萄球菌感染的疗效比较显示文摘甲氧西林耐药金葡菌(MRSA)感染可选择的治疗药物有限,多年来万古霉素是治疗的金标准。对万古霉素敏感性下降菌株的出现,增加了对新型抗感染药物的需求,噁唑烷酮类药物利奈唑胺是治疗MRSA感染的新药。然而,评价该药临床疗效的研究较少。 | Caffrey AR Quilliam BJ Laplante KL 秦晓华(摘译) 王明贵(审校) | 2011 | 中国感染与化疗杂志2011，11，4： | 2 |
| 3 | BCR-ABL inducedoncogenesis is mediated by direct interaction with the SH2 domain ofthe GRB-2 adaptor protein显示文摘 | Pendergast AM Quilliam LA Cripe LD | 1993 | Cell1993，75，1： | 1 |
| 4 | The role of chromatography in the hunt for red tide toxins显示文摘 | Michael A Quilliam | 2003 | Journal of Chromatography A2003，，1： | 1 |
| 5 | Analysis of eyanobaeterial toxins by hydrophilie interaction liquid chromatography- mass spectrometry 显示文摘 | Dell' Aversano C Eaglesham G K Quilliam M A | 2004 | Journal of Chromatography A2004，1028，： | 1 |
| 6 | An idiotypic-anti-idiotypic competitive immunoassay for quantitation of okadaic acid显示文摘 | Shestowsky W S Quilliam M A sikorska H M | 1992 | Toxicon1992，30，： | 1 |
| 7 | Hydrophilic interaction liquid chromatography-mass spectrometry for the analysis of paralytic shellfish poisoning (PSP) toxins显示文摘 | Dell'Aversano C Hess P Quilliam M A | 2005 | J Chromatogr A2005，1081，2： | 1 |
| 8 | Headspace vapors from cereal grains 显示文摘 | Hougen J F W Quilliam M A Curran W A | 1971 | J Agri Food Chemistry1971，19，1： | 1 |
| 9 | Quantitative 1H NMR with external standards: use in preparation of calibration solu- tions for algal toxins and other natural products 显示文摘 | Burton I W Quilliam M A Walter J A | 2005 | Anal Chem2005，77，10： | 1 |
| 10 | Increased bioavailability of metals in two contrasting agricultural soils treated with waste wood-derived biochar and ash显示文摘 | LUCCHINI P QUILLIAM R S DELUCA T H | 2014 | Environ Sci Pollut Res2014，21，5： | 1 |
| 11 | Alternatives to potentially inappropriate medications for use in e-prescribing software: Triggers and treatment algorithms 显示文摘 | Hume AL Quilliam BJ Goldman R | 2011 | BMJ Qual Saf2011，20，10： | 1 |
| 12 | Does biochar application alter heavy metal dynamics in agricultural soil?显示文摘 | Lucchini P Quilliam R S DeLuca T H | 2014 | Agriculture Ecosystems & Environment2014，184，： | 1 |
| 13 | Clinical correlates and drug treatment of residents with stroke in long-term care 显示文摘 | Quilliam BJ Lapane KL | 2001 | Stroke2001，32，6： | 1 |
| 14 | The toxigenic marine dinoflagellate Alexandrium tamarense as the probabe cause ofmortality of caged salmon in Nova Scotia显示文摘 | CEMBELLA A D QUILLIAM M A LEWIS N L | 2002 | Harmful Algae2002，，1： | 1 |
| 15 | Nutrient Dy- namics, Microbial Growth and Weed Emergence in Biochar Amended Soil Are Influenced by Time Since Application and Re- application Rate 显示文摘 | QUILLIAM R S MARSDEN K A GERTLER C | 2012 | Agriculture Ecosystems and Environment2012，158，1： | 1 |
| 16 | Differential activation of the Ras/extracellular- signal - regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase显示文摘 | Fridell YW Jin Y Quilliam LA | 1996 | Mol Cell Biol1996，16，1： | 1 |
| 17 | BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein显示文摘 | Pendergast A M Quilliam L A Cripe L D | 1993 | Cell1993，75，1： | 1 |
| 18 | Nutrient dynamics, microbial growth and weed emergence in biochar amended soil are influenced by time since appli- cation and reapplication rate显示文摘 | Quilliam R S Marsden K A Gertler C | 2012 | Agriculture Ecosys- tems & Environment2012，158，： | 1 |
| 19 | Analysis of cyanobacterial toxins by hydrophilic interaction liquid chromatography-massspectrometry显示文摘 | Aversano D Eaglesham C Quilliam G K | 2004 | J Chromatogr A2004，1028，： | 1 |
| 20 | Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins 显示文摘 | Quilliam L A Khosravi-Far R Huff SY | 1995 | Bioessays1995，17，5： | 1 |
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